Search Results - "Klapper, Paul E"

Single and multiple respiratory virus infections and severity of respiratory disease: A systematic review by Goka, Edward Anthony, Vallely, Pamela J, Mutton, Kenneth J, Klapper, Paul E

“…Abstract Introduction There are suggestions that virus co-infections may influence the clinical outcome of respiratory virus illness. We performed a systematic…”
Get full text

Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune recovery by Chakrabarti, Suparno, Mautner, Vivien, Osman, Husam, Collingham, Kathryn E., Fegan, Chris D., Klapper, Paul E., Moss, Paul A.H., Milligan, Donald W.

“…Adenovirus infections occur in 5% to 21% of patients following stem cell transplantation (SCT), with an associated mortality of up to 50%. However, a lack of…”
Get full text

Performance of antigen lateral flow devices in the UK during the alpha, delta, and omicron waves of the SARS-CoV-2 pandemic: a diagnostic and observational study by Eyre, David W, Futschik, Matthias, Tunkel, Sarah, Wei, Jia, Cole-Hamilton, Joanna, Saquib, Rida, Germanacos, Nick, Dodgson, Andrew R, Klapper, Paul E, Sudhanva, Malur, Kenny, Chris, Marks, Peter, Blandford, Edward, Hopkins, Susan, Peto, Tim E A, Fowler, Tom

“…Antigen lateral flow devices (LFDs) have been widely used to control SARS-CoV-2. We aimed to improve understanding of LFD performance with changes in variant…”
Get full text

Comparative evaluation of swabbing sites for Omicron variant detection in PCR testing by Fowler, Tom, Blandford, Edward, Chapman, David, Futschik, Matthias E., Kulasegaran-Shylini, Raghavendran, Tunkel, Sarah, Lewis, Carolyn, Fellows, Alasdair, Sheppard, Ellie, McCabe, Leanne, Marks, Peter, Klapper, Paul E., Dodgson, Andrew, Sudhanva, Malur, Kidd, Mike, Vail, Andy, Hopkins, Susan, Peto, Tim

“…•Throat swab has a higher sensitivity than nose swabs for detecting the Omicron Variant of SARS-CoV-2 with PCR.•Viral concentration (VC) in nose samples is…”
Get full text

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure by López-Labrador, F. Xavier, Brown, Julianne R., Fischer, Nicole, Harvala, Heli, Van Boheemen, Sander, Cinek, Ondrej, Sayiner, Arzu, Madsen, Tina Vasehus, Auvinen, Eeva, Kufner, Verena, Huber, Michael, Rodriguez, Christophe, Jonges, Marcel, Hönemann, Mario, Susi, Petri, Sousa, Hugo, Klapper, Paul E., Pérez-Cataluňa, Alba, Hernandez, Marta, Molenkamp, Richard, der Hoek, Lia van, Schuurman, Rob, Couto, Natacha, Leuzinger, Karoline, Simmonds, Peter, Beer, Martin, Höper, Dirk, Kamminga, Sergio, Feltkamp, Mariet C.W., Rodríguez-Díaz, Jesús, Keyaerts, Els, Nielsen, Xiaohui Chen, Puchhammer-Stöckl, Elisabeth, Kroes, Aloys C.M., Buesa, Javier, Breuer, Judy, Claas, Eric C.J., de Vries, Jutte J.C.

“…•A European Network on Next-Generation Sequencing (ENNGS) has been established.•Recommendations for the implementation of viral metagenomic high-throughput…”
Get full text

Rapid antigen testing for SARS-CoV-2 by lateral flow assay: A field evaluation of self- and professional testing at UK community testing sites by Futschik, Matthias E., Johnson, Samuel, Turek, Elena, Chapman, David, Carr, Simon, Thorlu-Bangura, Zareen, Klapper, Paul E., Sudhanva, Malur, Dodgson, Andrew, Cole-Hamilton, Joanna R., Germanacos, Nick, Kulasegaran-Shylini, Raghavendran, Blandford, Edward, Tunkel, Sarah, Peto, Timothy, Hopkins, Susan, Fowler, Tom

“…•Self-testing by LFD is only marginally less sensitive than professional LFD testing.•LFD self-testing tends to be associated with a higher void rate.•LFD…”
Get full text

Double testing with lateral flow antigen test devices for COVID-19: does a second test in quick succession add value? by Futschik, Matthias E., Tunkel, Sarah A., Turek, Elena, Chapman, David, Thorlu-Bangura, Zareen, Kulasegaran-Shylini, Raghavendran, Blandford, Edward, Dodgson, Andrew, Klapper, Paul E., Sudhanva, Malur, Crook, Derrick, Bell, John, Hopkins, Susan, Peto, Tim, Fowler, Tom

“…We investigated if performing two lateral flow device (LFD) tests, LFD2 immediately after LFD1, could improve diagnostic sensitivity or specificity for…”
Get full text

Swab pooling enables rapid expansion of high-throughput capacity for SARS-CoV-2 community testing by Fagg, Jamie, Beale, Rupert, Futschik, Matthias E., Turek, Elena, Chapman, David, Halstead, Susan, Jones, Marc, Cole-Hamilton, Joanna, Gunson, Rory, Sudhanva, Malur, Klapper, Paul E., Vansteenhouse, Harper, Tunkel, Sarah, Dominiczak, Anna, Peto, Timothy EA, Fowler, Tom

“…•Pooling at source does not require changes in high-throughput testing pipeline.•High concordance (> 97%) of results for pooled and individual…”
Get full text

Multitypic Hepatitis C Virus Infection Identified by Real-Time Nucleotide Sequencing of Minority Genotypes by Buckton, Andrew J, Ngui, Siew-Lin, Arnold, Catherine, Boast, Katie, Kovacs, Joanne, Klapper, Paul E, Patel, Bharat, Ibrahim, Imad, Rangarajan, Savita, Ramsay, Mary E, Teo, Chong-Gee

“…The prevalence of concurrent multitypic hepatitis C virus (HCV) infection is uncertain. A sensitive and specific approach to identifying minority HCV genotypes…”
Get full text

Epidemiology of posttransplantation lymphoproliferative disorder in adult renal transplant recipients by Morton, Muir, Coupes, Beatrice, Roberts, Stephen A, Klapper, Paul E, Byers, Richard J, Vallely, Pamela J, Ryan, Kate, Picton, Michael L

“…There is little information in the literature describing the relationship between posttransplantation lymphoproliferative disorder (PTLD) incidence and…”
Get full text

Reliability of Nucleic Acid Amplification Methods for Detection of Chlamydia trachomatis in Urine: Results of the First International Collaborative Quality Control Study among 96 Laboratories by VERKOOYEN, Roel P, NOORDHOEK, Gerda T, KLAPPER, Paul E, REID, Jim, SCHIRM, Jurjen, CLEATOR, Graham M, IEVEN, Margareta, HODDEVIK, Gunnar

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Three Nonfatal Cases of Neonatal Adenovirus Infection by Elnifro, Elfateh M, Cooper, Robert J, Dady, Ian, Hany, Sa'id, Mughal, Zolf M, Klapper, Paul E

“…Neonatal adenovirus infection is considered a rare and fatal disease. Three nonfatal neonatal adenovirus infections manifesting as conjunctivitis or…”
Get full text

External Quality Assessment Program for Qualitative and Quantitative Detection of Hepatitis C Virus RNA in Diagnostic Virology by SCHIRM, Jurjen, VAN LOON, Anton M, VALENTINE-THON, Elizabeth, KLAPPER, Paul E, REID, Jim, CLEATOR, Graham M

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

European Proficiency Testing Program for Molecular Detection and Quantitation of Hepatitis B Virus DNA by Valentine-Thon, Elizabeth, van Loon, Anton M., Schirm, Jurjen, Reid, Jim, Klapper, Paul E., Cleator, Graham M.

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Merkel cell polyomavirus DNA in immunocompetent and immunocompromised patients with respiratory disease by Abedi Kiasari, Bahman, Vallely, Pamela J., Klapper, Paul E.

“…Merkel cell polyomavirus (MCPyV) was identified originally in association with a rare but aggressive skin cancer, Merkel cell carcinoma. The virus has since…”
Get full text

Performance of self-collected saliva samples for SARS-CoV-2 mass testing in community settings by Kay, Olivia, Futschik, Matthias E, Turek, Elena, Chapman, David, Carr, Simon, Sudhanva, Malur, Klapper, Paul E., Cox, Tony, Hill, Michael, Cole-Hamilton, Joanna, Marks, Peter, Tunkel, Sarah A, Peto, Timothy, Davies, Lindsey, Fowler, Tom

“…Saliva has been considered a suitable sample material for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA testing, but uncertainty remained…”
Get full text

Multicenter Proficiency Testing of Nucleic Acid Amplification Methods for the Detection of Enteroviruses by VAN VLIET, Karin E, MUIR, Peter, ECHEVARRIA, Jose M, KLAPPER, Paul E, CLEATOR, Graham M, VAN LOON, Anton M

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Post-transplant lymphoproliferative disorder in adult renal transplant recipients: survival and prognosis by Morton, Muir, Coupes, Beatrice, Ritchie, James, Roberts, Stephen A, Klapper, Paul E, Byers, Richard J, Vallely, Pamela J, Ryan, Kate, Picton, Michael L

“…Post-transplant lymphoproliferative disorder (PTLD) is a rare, serious complication following solid organ transplantation, with an incidence of 2.6 cases per…”
Get full text

Multiplex PCR : Optimization and application in diagnostic virology by ELNIFRO, Elfath M, ASHSHI, Ahmed M, COOPER, Robert J, KLAPPER, Paul E

“…PCR has revolutionized the field of infectious disease diagnosis. To overcome the inherent disadvantage of cost and to improve the diagnostic capacity of the…”
Get full text

Childhood encephalopathy: viruses, immune response, and outcome by Clarke, Michael, Newton, Richard W, Klapper, Paul E, Sutcliffe, H, Laing, I, Wallace, Geoff

“…This study examined children with an acute encephalopathy illness for evidence of viral infection, disordered blood–brain barrier function, intrathecal…”
Get full text