Search Results - "Klanke, B"

The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis by Buchholz, Bjoern, Klanke, Bernd, Schley, Gunnar, Bollag, Gideon, Tsai, James, Kroening, Sven, Yoshihara, Daisuke, Wallace, Darren P., Kraenzlin, Bettina, Gretz, Norbert, Hirth, Peter, Eckardt, Kai-Uwe, Bernhardt, Wanja M.

“…Background. Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of renal failure. Aberrant epithelial cell proliferation is a major cause of…”
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Blood pressure versus direct mineralocorticoid effects on kidney inflammation and fibrosis in DOCA-salt hypertension by Klanke, Bernd, Cordasic, Nada, Hartner, Andrea, Schmieder, Roland E., Veelken, Roland, Hilgers, Karl F.

“…Objective. We examined the contribution of high blood pressure versus direct mineralocorticoid effects to the progression of kidney inflammation and fibrosis…”
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Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis by Schley, Gunnar, Klanke, Bernd, Kalucka, Joanna, Schatz, Valentin, Daniel, Christoph, Mayer, Marleen, Goppelt-Struebe, Margarete, Herrmann, Martin, Thorsteinsdottir, Margret, Palsson, Runolfur, Beneke, Angelika, Katschinski, Dörthe M, Burzlaff, Nicolai, Eckardt, Kai-Uwe, Weidemann, Alexander, Jantsch, Jonathan, Willam, Carsten

“…Prolyl hydroxylase domain enzyme inhibitors (PHDIs) stabilize hypoxia-inducible factors (HIFs), and are protective in models of acute ischemic and inflammatory…”
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Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney by Klanke, B, Simon, M, Röckl, W, Weich, H A, Stolte, H, Gröne, H J

“…BACKGROUND: Vascular endothelial growth factor (VEGF) or vascular permeability factor (VPF) is a selective mitogen for endothelial cells; it increases…”
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Importance of NO/EDRF for glomerular and tubular function: Studies in the isolated perfused rat kidney by Radermacher, Jörg, Klanke, Bernd, Schurek, Hans-Joachim, Stolte, Hilmar F., Frölich, Jürgen C.

“…Importance of NO/EDRF for glomerular and tubular function: Studies in the isolated perfused rat kidney. The effect of the addition of Nω-nitro-L-arginine…”
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Kidney injury is independent of endothelial HIF-1α by Kalucka, Joanna, Schley, Gunnar, Georgescu, Adela, Klanke, Bernd, Rössler, Susanne, Baumgartl, Jasmin, Velden, Joachim, Amann, Kerstin, Willam, Carsten, Johnson, Randall S., Eckardt, Kai-Uwe, Weidemann, Alexander

“…Hypoxia-inducible transcription factors (HIFs) control cellular adaptation to low oxygen. In the kidney, activation of HIF is beneficial during injury;…”
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Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice by Hartner, Andrea, Cordasic, Nada, Klanke, Bernd, Veelken, Roland, Hilgers, Karl F.

“…Background. The genetic background may exert important modifying effects on the course and severity of experimental kidney diseases in mice. We investigated…”
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Effect of arginine depletion on glomerular and tubular kidney function: studies in isolated perfused rat kidneys by Radermacher, J, Klanke, B, Kastner, S, Haake, G, Schurek, H J, Stolte, H F, Frölich, J C

“…The effect of L-Arg depletion on glomerular hemodynamics and tubular function of isolated rat kidneys perfused with a medium containing 21 amino acids has been…”
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The Tumor Gene Survivin Is Highly Expressed in Adult Renal Tubular Cells: Implications for a Pathophysiological Role in the Kidney by Lechler, Philipp, Wu, Xiaoqing, Bernhardt, Wanja, Campean, Valentina, Gastiger, Susanne, Hackenbeck, Thomas, Klanke, Bernd, Weidemann, Alexander, Warnecke, Christina, Amann, Kerstin, Engehausen, Dirk, Willam, Carsten, Eckardt, Kai-Uwe, Rodel, Franz, Wiesener, Michael Sean

“…The inhibitor of apoptosis protein survivin is of critical importance for regulation of cellular division and survival. Published data point to a restricted…”
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EFFECTS OF MTOR-INHIBITION ON HYPOXIC ADAPTATION BY HIF – PREFERENTIAL INFLUENCE ON ERYTHROPIETIN REGULATION: 540 by Wiesener, M, Knaup, K, Jozefowski, K, Klanke, B, Weidemann, A, Warnecke, C, Bernhardt, W, Eckardt, K -U.

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Role of fibrillin-1 in hypertensive and diabetic glomerular disease by Hartner, Andrea, Schaefer, Liliana, Porst, Markus, Cordasic, Nada, Gabriel, Anke, Klanke, Bernd, Reinhardt, Dieter P, Hilgers, Karl F

“…The microfibrillar protein fibrillin-1 is a component of the mesangial matrix. Defects in fibrillin-1 predisposes individuals to vascular damage in Marfan…”
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Adrenomedullin reduces mesangial cell number and glomerular inflammation in experimental mesangioproliferative glomerulonephritis by Plank, Christian, Hartner, Andrea, Klanke, Bernd, Geissler, Bettina, Porst, Markus, Amann, Kerstin, Hilgers, Karl F., Rascher, Wolfgang, Datsch, Jörg

“…Adrenomedullin reduces mesangial cell number and glomerular inflammation in experimental mesangioproliferative glomerulonephritis. Adrenomedullin (ADM) is a…”
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HIGH BLOOD PRESSURE AND NON-HEMODYNAMIC MINERALOCORTICOID EFFECTS MEDIATE GLOMERULAR INFLAMMATION AND INJURY IN HYPERTENSIVE NEPHROSCLEROSIS: P2.237 by Hilgers, K. F., Klanke, B., Cordasic, N., Hartner, A., Veelken, R.

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Both blood pressure and direct mineralocorticoid effects mediate glomerular inflammation and injury in DOCA-salt hypertension by Hilgers, Karl F., Klanke, Bernd, Hartner, Andrea, Schmieder, Roland E., Veelken, Roland

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Transplantation‐Induced Functional/Morphological Changes in Rat Aorta Allografts Differ from Those in Arteries of Rat Kidney Allografts by Andriambeloson, Emile, Cannet, Catherine, Pally, Charles, Klanke, Bernd, Bruns, Christian, Zerwes and, Hans‐Günter, Bigaud, Marc

“…The functional/morphological changes observed in rat aorta allografts were compared with those seen in the arteries of rat kidney allografts. Untreated…”
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A mouse model to assess endothelial activation in vivo by targeted insertion of alkaline phosphatase into the E-selectin gene by Luyten, Marcel A., Hofmann, Matthias, Käslin, Edgar, Klanke, Bernd, Pally, Charles, Kawai, Ryosei, Zerwes, Hans-Günter

“…We have developed a novel and noninvasive animal model in which the activity of a marker enzyme in plasma is used to measure endothelial cell activation…”
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Enhanced renal allograft rejection by inhibitors of nitric oxide synthase: a nonimmunologic influence on alloreactivity by Stojanovic, T, Gröne, H J, Gieseler, R K, Klanke, B, Schlemminger, R, Tsikas, D, Gröne, E F

“…Clinical and experimental studies indicate that nonimmunologic factors may modulate the alloreactivity of a renal transplant. Nitric oxide (NO) is an essential…”
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