Search Results - "Klaassen, Remco V."

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95 by Compans, Benjamin, Camus, Come, Kallergi, Emmanouela, Sposini, Silvia, Martineau, Magalie, Butler, Corey, Kechkar, Adel, Klaassen, Remco V., Retailleau, Natacha, Sejnowski, Terrence J., Smit, August B., Sibarita, Jean-Baptiste, Bartol, Thomas M., Perrais, David, Nikoletopoulou, Vassiliki, Choquet, Daniel, Hosy, Eric

“…Long-term depression (LTD) of synaptic strength can take multiple forms and contribute to circuit remodeling, memory encoding or erasure. The generic term LTD…”
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Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity by Klaassen, Remco V., Stroeder, Jasper, Coussen, Françoise, Hafner, Anne-Sophie, Petersen, Jennifer D., Renancio, Cedric, Schmitz, Leanne J. M., Normand, Elisabeth, Lodder, Johannes C., Rotaru, Diana C., Rao-Ruiz, Priyanka, Spijker, Sabine, Mansvelder, Huibert D., Choquet, Daniel, Smit, August B.

“…Trafficking and biophysical properties of AMPA receptors (AMPARs) in the brain depend on interactions with associated proteins. We identify Shisa6, a single…”
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Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex by Pandya, Nikhil J., Klaassen, Remco V., van der Schors, Roel C., Slotman, Johan A., Houtsmuller, Adriaan, Smit, August B., Li, Ka Wan

“…The group 1 metabotropic glutamate receptors 1 and 5 (mGluR1/5) have been implicated in mechanisms of synaptic plasticity and may serve as potential…”
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The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory by Schmitz, Leanne J M, Klaassen, Remco V, Ruiperez-Alonso, Marta, Zamri, Azra Elia, Stroeder, Jasper, Rao-Ruiz, Priyanka, Lodder, Johannes C, van der Loo, Rolinka J, Mansvelder, Huib D, Smit, August B, Spijker, Sabine

“…Glutamatergic synapses rely on AMPA receptors (AMPARs) for fast synaptic transmission and plasticity. AMPAR auxiliary proteins regulate receptor trafficking,…”
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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors by Sixma, Titia K, Brejc, Katju a, van Dijk, Willem J, Klaassen, Remco V, Schuurmans, Mascha, van der Oost, John, Smit, August B

“…Pentameric ligand gated ion-channels, or Cys-loop receptors, mediate rapid chemical transmission of signals. This superfamily of allosteric transmembrane…”
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Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer's Disease Mouse Model by Thanou, Evangelia, Koopmans, Frank, Pita-Illobre, Débora, Klaassen, Remco V, Özer, Berna, Charalampopoulos, Ioannis, Smit, August B, Li, Ka Wan

“…Suspension TRAPping filter (sTRAP) is an attractive sample preparation method for proteomics studies. The sTRAP protocol uses 5% SDS that maximizes protein…”
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Crystal Structure of Acetylcholine-binding Protein from Bulinus truncatus Reveals the Conserved Structural Scaffold and Sites of Variation in Nicotinic Acetylcholine Receptors by Celie, Patrick H.N., Klaassen, Remco V., van Rossum-Fikkert, Sarah E., van Elk, René, van Nierop, Pim, Smit, August B., Sixma, Titia K.

“…The crystal structure of acetylcholine-binding protein (AChBP) from the mollusk Lymnaea stagnalis is the established model for the ligand binding domains of…”
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C-terminal interactors of the AMPA receptor auxiliary subunit Shisa9 by Karataeva, Anna R, Klaassen, Remco V, Ströder, Jasper, Ruiperez-Alonso, Marta, Hjorth, Johannes J J, van Nierop, Pim, Spijker, Sabine, Mansvelder, Huibert D, Smit, August B

“…Shisa9 (initially named CKAMP44) has been identified as auxiliary subunit of the AMPA-type glutamate receptors and was shown to modulate its physiological…”
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MS-DAP Platform for Downstream Data Analysis of Label-Free Proteomics Uncovers Optimal Workflows in Benchmark Data Sets and Increased Sensitivity in Analysis of Alzheimer’s Biomarker Data by Koopmans, Frank, Li, Ka Wan, Klaassen, Remco V., Smit, August B.

“…In the rapidly moving proteomics field, a diverse patchwork of data analysis pipelines and algorithms for data normalization and differential expression…”
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Auxiliary subunits of the AMPA: The Shisa family of proteins by Abdollahi Nejat, Mazyar, Klaassen, Remco V, Spijker, Sabine, Guus Smit, August B

“…AMPA receptors mediate fast synaptic transmission in the CNS and can assemble with several types of auxiliary proteins in a spatio-temporal manner, from newly…”
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Auxiliary subunits of the AMPA receptor: The Shisa family of proteins by Abdollahi Nejat, Mazyar, Klaassen, Remco V., Spijker, Sabine, Smit, August B.

“…AMPA receptors mediate fast synaptic transmission in the CNS and can assemble with several types of auxiliary proteins in a spatio-temporal manner, from newly…”
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AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation by Peter, Saša, Urbanus, Bastiaan H.A., Klaassen, Remco V., Wu, Bin, Boele, Henk-Jan, Azizi, Sameha, Slotman, Johan A., Houtsmuller, Adriaan B., Schonewille, Martijn, Hoebeek, Freek E., Spijker, Sabine, Smit, August B., De Zeeuw, Chris I.

“…The majority of excitatory postsynaptic currents in the brain are gated through AMPA-type glutamate receptors, the kinetics and trafficking of which can be…”
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Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes by Chen, Ning, Koopmans, Frank, Gordon, Aaron, Paliukhovich, Iryna, Klaassen, Remco V., van der Schors, Roel C., Peles, Elior, Verhage, Matthijs, Smit, August B., Li, Ka Wan

“…Autism is a human developmental brain disorder characterized by impaired social interaction and communication. Contactin-associated protein-like 2 (Caspr2,…”
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Inside Front Cover: Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex by Pandya, Nikhil J., Klaassen, Remco V., van der Schors, Roel C., Slotman, Johan A., Houtsmuller, Adriaan, Smit, August B., Li, Ka Wan

“…DOI: 10.1002/pmic.201500400Type 1‐metabotropic glutamate receptors in the brain control long term synaptic plasticity and are considered important drug targets…”
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Correction: The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory by Schmitz, Leanne J M, Klaassen, Remco V, Ruiperez-Alonso, Marta, Zamri, Azra Elia, Stroeder, Jasper, Rao-Ruiz, Priyanka, Lodder, Johannes C, van der Loo, Rolinka J, Mansvelder, Huib D, Smit, August B, Spijker, Sabine

“…For context, the subcellular distribution analysis of Shisa7 (Figure 1d) had been performed in parallel with that of the previously published analysis for…”
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