Search Results - "Kjellén, Peter"

Allelic variations in rat MHC class II binding of myelin basic protein peptides correlate with encephalitogenicity by de Graaf, Katrien L., Weissert, Robert, Kjellén, Peter, Holmdahl, Rikard, Olsson, Tomas

“…The impact of the strength and promiscuity of the self peptide–MHC class II interaction on susceptibility to autoimmune disease is uncertain. Here we studied…”
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TOM1L Is Involved in a Novel Signaling Pathway Important for the IL-2 Production in Jurkat T Cells Stimulated by CD3/CD28 CoLigation by ELMARGHANI, Ahmed, ABUABAID, Hanan, KJELLEN, Peter

“…TOM1L (target of Myb-1 Like) was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we…”
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Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis by Holm, Lotta, Kjellén, Peter, Holmdahl, Rikard, Kihlberg, Jan

“…The minimal peptide epitope required for binding to MHC-II molecules associated with arthritis in mice, was determined to be CII260–266. Elongation to give…”
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Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis by Kjellén, P, Issazadeh, S, Olsson, T, Holmdahl, R

“…A protracted and relapsing form of experimental allergic encephalomyelitis (EAE) develops in the DA rat after immunization with rat spinal cord homogenate…”
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The H2-Ab gene influences the severity of experimental allergic encephalomyelitis induced by proteolipoprotein peptide 103–116 by Kjellén, Peter, Jansson, Liselotte, Vestberg, Mikael, Andersson, Åsa, Mattsson, Ragnar, Holmdahl, Rikard

“…Immunization of H2 p and H2 q congenic C3H mouse strains with the PLP 103–116 peptide elicited two distinct experimental allergic encephalomyelitis (EAE)…”
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Genetic control of collagen‐induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes by Johansson, Åsa C.M., Sundler, Martin, Kjellén, Peter, Johannesson, Martina, Cook, Andrew, Lindqvist, Anna‐Karin B, Nakken, Britt, Bolstad, Anne Isine, Jonsson, Roland, Alarcón‐Riquelme, Marta, Holmdahl, Rikard

“…The nonobese diabetic (NOD) mouse spontaneously develops autoimmune‐mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes…”
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Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells by Smith, CI, Baskin, B, Humire-Greiff, P, Zhou, JN, Olsson, PG, Maniar, HS, Kjellen, P, Lambris, JD, Christensson, B, Hammarstrom, L

“…The gene mutated in the human disease, X-linked agammaglobulinemia (XLA), is related to the Src gene family of cytoplasmic protein-tyrosine kinases and is…”
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Screening of several H-2 congenic mouse strains identified H-2(q) mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement by Abdul-Majid, K B, Jirholt, J, Stadelmann, C, Stefferl, A, Kjellén, P, Wallström, E, Holmdahl, R, Lassmann, H, Olsson, T, Harris, R A

“…We identified H-2(q) as a susceptible genotype for MOG-induced EAE by systematic screening of a series of H-2 congenic B10 mouse strains. A series of…”
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High MAPK p38 activity and low level of IL-10 in intermittent claudication as opposed to stable angina by El Marghani, A M, Abuabaid, H M, Hurtig-Wennlöf, A, Sirsjö, A, Norgren, L, Kjellen, P

“…The aim of the present pilot study was to relate the activity of MAPK p38 with the levels of pro- and anti-inflammatory cytokines in a small cohort of patients…”
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Major histocompatibility complex-controlled protective influences on experimental autoimmune encephalomyelitis are peptide specific by Issazadeh, S, Kjellén, P, Olsson, T, Mustafa, M, Holmdahl, R

“…The myelin basic protein (MBP) peptide 63-88-induced experimental autoimmune encephalomyelitis (EAE) and its associated T cell cytokine profile are influenced…”
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TOM1L Is Involved in a Novel Signaling Pathway Important for the IL-2 Production in Jurkat T Cells Stimulated by CD3/CD28 CoLigation by Elmarghani, Ahmed, Abuabaid, Hanan, Kjellen, Peter

“…TOM1L (target of Myb-1 Like) was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we…”
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TOM1L Is Involved in a Novel Signaling Pathway Important for the IL-2 Production in Jurkat T Cells Stimulated by CD3/CD28CoLigation by Elmarghani, Ahmed, Abuabaid, Hanan, Kjellen, Peter

“…TOM1L (target of Myb-1 Like) was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we…”
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Screening of several H-2 congenic mouse strains identified H-2q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement by Abdul-Majid, Khairul-Bariah, Jirholt, Johan, Stadelmann, Christine, Stefferl, Andreas, Kjellén, Peter, Wallström, Erik, Holmdahl, Rikard, Lassmann, Hans, Olsson, Tomas, Harris, Robert A.

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Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri Tip by Weis, David D., Kjellen, Peter, Sefton, Bartholomew M., Engen, John R.

“…The Tip protein from Herpesvirus saimiri interacts with the SH3 domain from the Src‐family kinase Lck via a proline‐containing sequence termed LBD1. Src‐family…”
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Screening of several H-2 congenic mouse strains identified H-2 q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement by Abdul-Majid, Khairul-Bariah, Jirholt, Johan, Stadelmann, Christine, Stefferl, Andreas, Kjellén, Peter, Wallström, Erik, Holmdahl, Rikard, Lassmann, Hans, Olsson, Tomas, Harris, Robert A.

“…We identified H-2 q as a susceptible genotype for MOG-induced EAE by systematic screening of a series of H-2 congenic B10 mouse strains. A series of H-2…”
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TOM1L is involved in a novel signaling pathway important for the IL-2 production in Jurkat T cells stimulated by CD3/CD28 co-ligation by Elmarghani, Ahmed, Abuabaid, Hanan, Kjellen, Peter

“…TOM1L (target of Myb-1 Like) was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we…”
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Type II Collagen in Cartilage Evokes Peptide-specific Tolerance and Skews the Immune Response by Malmström, Vivianne, Kjellén, Peter, Holmdahl, Rikard

“…T cell recognition of type II collagen (CII) is a crucial event in the induction of collagen-induced arthritis in the mouse. Several CII peptides have been…”
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The structural basis of MHC control of collagen‐induced arthritis; binding of the immunodominant type II collagen 256 – 270 glycopeptide to H‐2Aq and H‐2Ap molecules by Kjellén, Peter, Brunsberg, Ulrica, Broddefalk, Johan, Hansen, Bjarke, Vestberg, Mikael, Ivarsson, Ianeric, Engström, Åke, Svejgaard, Arne, Kihlberg, Jan, Fugger, Lars, Holmdahl, Rikard

“…The Aq major histocompatibility complex (MHC) class II molecule is associated with susceptibility to murine collagen‐induced arthritis (CIA), whereas the…”
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Novel galanin receptor ligands by POOGA, MARGUS, JURÉUS, ANDERS, REZAEI, KHADIJEH, HASANVAN, HOMA, SAAR, KÜLLIKI, KASK, KALEV, KJELLÉN, PETER, LAND, TIIT, HALONEN, JUHA, MÄEORG, UNO, URI, ASKO, SOLYOM, SANDOR, BARTFAI, TAMAS, LANGEL, ÜLO

“…Galanin is a neuroendocrine peptide which is 29/30 amino acids in length and is recognised by G‐protein‐coupled central nervous system receptors via its…”
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The Herpesvirus Saimiri Tip484 and Tip488 Proteins Both Stimulate Lck Tyrosine Protein Kinase Activity in Vivo and in Vitro by Kjellen, Peter, Amdjadi, Kambiz, Lund, Troy C., Medveczky, Peter G., Sefton, Bartholomew M.

“…Herpesvirus saimiri (HVS) of subgroup C efficiently induces leukemia in New World primates and transforms human lymphocytes. The viral tyrosine kinase…”
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