Search Results - "Kjaer, Mette S."

Review article: The need for more efficient and patient‐oriented drug development pathways in NASH—setting the scene for platform trials by Pericàs, Juan M., Di Prospero, Nicholas A., Anstee, Quentin M., Mesenbrinck, Peter, Kjær, Mette S., Rivera‐Esteban, Jesús, Koenig, Franz, Sena, Elena, Pais, Raluca, Manzano, Ramiro, Genescà, Joan, Tacke, Frank, Ratziu, Vlad, DiProspero, Nicholas A., Ratziu, Vlad, Pericàs, Juan M., Kjær, Mette S., Anstee, Quentin M., Tacke, Frank, Mesenbrinck, Peter, Rivera‐Esteban, Jesús, Koenig, Franz, Sena, Elena, Manzano, Ramiro, Genescà, Joan, Pais, Raluca, Kara, Leila, Meyer, Elias, Duca, Anna, Kline, Timothy, Aaes‐Jørgensen, Anders, Balthaus, Tania, Preville, Natalie, Zhang, Lingjiao, Capuano, George, Morello, Salvatore, Mielke, Tobias, Penna, Sabina H., Posch, Martin

“…Summary Background and Aims Non‐alcoholic steatohepatitis (NASH) constitutes a significant unmet medical need with a burgeoning field of clinical research and…”
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Predictors of heavy drinking after liver transplantation for alcoholic liver disease in Denmark (1990-2013): a nationwide study with competing risks analyses by Askgaard, Gro, Tolstrup, Janne S, Gerds, Thomas A, Hamberg, Ole, Zierau, Louise, Kjær, Mette S

“…Objective. Heavy drinking following liver transplantation decreases survival. Little is known of predictors of heavy drinking, which should guide clinicians…”
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Prognostic utility of Fibrosis-4 Index for risk of subsequent liver and cardiovascular events, and all-cause mortality in individuals with obesity and/or type 2 diabetes: a longitudinal cohort study by Anstee, Quentin M, Berentzen, Tina L, Nitze, Louise M, Jara, Maximilian, Jensen, Anders B, Kjær, Mette S, Mangla, Kamal K, Tarp, Jens M, Khunti, Kamlesh

“…The Fibrosis-4 Index (FIB-4) is used as a non-invasive tool for the presence of advanced liver fibrosis in metabolic dysfunction-associated steatotic liver…”
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Outcome and adverse events in patients with chronic hepatitis C treated with direct-acting antivirals: a clinical randomized study by Sølund, Christina, Andersen, Ellen S, Mössner, Belinda, Laursen, Alex L, Røge, Birgit T, Kjær, Mette S, Gerstoft, Jan, Christensen, Peer B, Pedersen, Martin S, Schønning, Kristian, Fahnøe, Ulrik, Bukh, Jens, Weis, Nina

“…OBJECTIVENew potent direct-acting antiviral (DAA) regimens against hepatitis C virus have been approved in recent years. However, information about the rate of…”
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Alcohol drinking pattern and risk of alcoholic liver cirrhosis: A prospective cohort study by Askgaard, Gro, Grønbæk, Morten, Kjær, Mette S, Tjønneland, Anne, Tolstrup, Janne S

“…Graphical abstract…”
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Opportunities to Prevent Alcoholic Liver Cirrhosis in High-Risk Populations: A Systematic Review With Meta-Analysis by Askgaard, Gro, Kjær, Mette S, Tolstrup, Janne S

“…Alcoholic liver cirrhosis is preventable and caused by heavy drinking. Few in the general population may be at risk and interventions targeting individuals at…”
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Paediatric hepatitis B and hepatitis C virus infections: An observational study of a Danish cohort by Norden, Christoph, Malham, Mikkel, Nordly, Sannie, Grosen, Dorthe, Kvistgaard, Helene, Kjær, Mette S., Brix Christensen, Vibeke

“…Aim The aim of this study was to describe the epidemiological and clinical characteristics in children with either chronic hepatitis B virus (HBV) or hepatitis…”
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Number of hospital contacts with alcohol problems predicts later risk of alcoholic liver cirrhosis by ASKGAARD, GRO, TOLSTRUP, JANNE S., KJÆR, METTE S., LEON, DAVID A.

“…Aims: Alcoholic liver cirrhosis is usually preceded by years of heavy drinking. We investigated whether the risk of alcoholic liver cirrhosis increases as the…”
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FibroScan-aspartate aminotransferase (FAST) score for monitoring histological improvement in non-alcoholic steatohepatitis activity during semaglutide treatment: post-hoc analysis of a randomised, double-blind, placebo-controlled, phase 2b trial by Wai-Sun Wong, Vincent, Anstee, Quentin M., Nitze, Louise M., Geerts, Anja, George, Jacob, Nolasco, Victor, Kjær, Mette S., Ladelund, Steen, Newsome, Philip N., Ratziu, Vlad

“…Currently, assessment of candidate pharmacotherapies in patients with non-alcoholic steatohepatitis (NASH) involves invasive liver biopsy. Non-invasive scores,…”
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Hospital contacts with alcohol problems prior to liver cirrhosis or pancreatitis diagnosis by Gro Askgaard S?ren Neermark David A Leon Mette S Kj?r Janne S Tolstrup

“…AIM To evaluate prior hospital contacts with alcohol problems in patients with alcoholic liver cirrhosis and pancreatitis. METHODS This was a register-based…”
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Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia by Larsen, Rikke Hebo, Kjær, Mette S, Eefsen, Martin, Larsen, Fin Stolze, Bjerring, Peter Nissen

“…AIM:To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin…”
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Risk for alcoholic liver cirrhosis after an initial hospital contact with alcohol problems: A nationwide prospective cohort study by Askgaard, Gro, Leon, David A., Kjær, Mette S., Deleuran, Thomas, Gerds, Thomas A., Tolstrup, Janne S.

“…Alcoholic liver cirrhosis is usually preceded by many years of heavy drinking, in which cessation in drinking could prevent the disease. Alcohol problems are…”
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453 NON-INVASIVE FIBROSIS SCORES AS PREDICTORS FOR CLINICAL EVENTS IN OBESITY: A LONGITUDINAL STUDY by Jara, Maximilian K., Anstee, Quentin M., Berentzen, Tina L., Nitze, Louise M., Kjær, Mette S., Mangla, Kamal K., Tarp, Jens M., Neuman, Joshua, Khunti, Kamlesh

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Liver biopsy performance and histological findings among patients with chronic viral hepatitis: A Danish database study by Brehm Christensen, Peer, Bygum Krarup, Henrik, Møller, Axel, Lund Laursen, Alex, Kjaer, Mette S., Orholm, Marianne, Lindberg, Jens, Groenbaek, Karin, Kromann-Andersen, Hans, Weis, Nina, THE DANHEP GROUP

“…We investigated the variance of liver biopsy frequency and histological findings among patients with chronic viral hepatitis attending 10 medical centres in…”
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Prognostic utility of Fibrosis-4 Index for risk of subsequent liver and cardiovascular events, and all-cause mortality in individuals with obesity and/or type 2 diabetes: a longitudinal cohort studyResearch in context panel by Quentin M. Anstee, Tina L. Berentzen, Louise M. Nitze, Maximilian Jara, Anders B. Jensen, Mette S. Kjær, Kamal K. Mangla, Jens M. Tarp, Kamlesh Khunti

“…Background: The Fibrosis-4 Index (FIB-4) is used as a non-invasive tool for the presence of advanced liver fibrosis in metabolic dysfunction-associated…”
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FibroScan-aspartate aminotransferase (FAST) score for monitoring histological improvement in non-alcoholic steatohepatitis activity during semaglutide treatment: post-hoc analysis of a randomised, double-blind, placebo-controlled, phase 2b trialResearch in context by Vincent Wai-Sun Wong, Quentin M. Anstee, Louise M. Nitze, Anja Geerts, Jacob George, Victor Nolasco, Mette S. Kjær, Steen Ladelund, Philip N. Newsome, Vlad Ratziu

“…Background: Currently, assessment of candidate pharmacotherapies in patients with non-alcoholic steatohepatitis (NASH) involves invasive liver biopsy…”
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Neurodevelopmental status at age five years of neonates treated with extracorporeal membrane oxygenation by Glass, Penny, Wagner, Ann E., Papero, Patricia H., Rajasingham, Shusila R., Civitello, Lucy A., Kjaer, Mette S., Coffman, Cara E., Getson, Pamela R., Short, Billie L.

“…Objective: To determine the neurodevelopmental status at age 5 years among children who received extracorporeal membrane oxygenation (ECMO) in the newborn…”
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Human fetal hand size and hand maturity in the first half of the prenatal period by Kjaer, Mette S., Kjaer, Inger

“…The purpose of the present study has been to establish radiographic standards of hand length and finger bone size in the first half of the prenatal period, and…”
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PET/DW-MRI for evaluating treatment in chronic hepatitis C patients by Petersen, Rikke J, Nielsen, Nick S, Johannesen, Helle H, Hansen, Adam E, Jespersen, Sofie, Arnbjerg, Caroline J, Löfgren, Johan, Kjær, Mette S, Clausen, Mette R, Kjær, Andreas, Nielsen, Susanne D, Fischer, Barbara M

“…This feasibility study set out to investigate the use of FDG-PET/DW-MRI in chronic hepatitis C patients to examine changes in local liver inflammation after…”
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Cyclosporin versus tacrolimus for liver transplanted patients by Haddad, E M, McAlister, V C, Renouf, E, Malthaner, R, Kjaer, M S, Gluud, L L

“…Most liver transplant recipients receive either cyclosporin or tacrolimus to prevent rejection. Both drugs inhibit calcineurin phosphatase which is thought to…”
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