Inpatient Weight Restoration Treatment Is Associated with Decrease in Post-Meal Anxiety

Inpatient Weight Restoration Treatment Is Associated with Decrease in Post-Meal Anxiety

Objective: Anorexia nervosa (AN) is characterized by weight loss, distorted body image with fear of becoming fat and associated with anxiety, especially in relation to food intake. Anxiety in relation to meals and weight restoration remains a major challenge in the treatment of AN. We examined the e...

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Bibliographic Details
Published in:Journal of personalized medicine Vol. 11; no. 11; p. 1079
Main Authors: Sjögren, Magnus, Kizilkaya, Ismail, Støving, Rene Klinkby
Format: Journal Article
Language:English
Published: Basel MDPI AG 24-10-2021
MDPI
Subjects:
Anorexia
Anorexia nervosa
Anxiety
Anxiety disorders
Autism
Body image
Body mass index
Body weight loss
Comorbidity
Eating behavior
Eating disorders
Food intake
Meal-intake
Meals
Mental depression
Mortality
Patients
Post-meal
Precision medicine
Psychopathology
Psychotherapy
Questionnaires
Weight restoration treatment
Denmark
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Summary:Objective: Anorexia nervosa (AN) is characterized by weight loss, distorted body image with fear of becoming fat and associated with anxiety, especially in relation to food intake. Anxiety in relation to meals and weight restoration remains a major challenge in the treatment of AN. We examined the effects of inpatient weight restoration treatment on levels of post-meal anxiety using visual analogue scale (VAS) ratings in patients with AN. Materials: Thirty-two patients with AN, all part of the PROspective Longitudinal all-comer inclusion study on Eating Disorders (PROLED) were followed over eight weeks with baseline psychometric measures and weekly VAS anxiety self-scoring. Methods: Apart from the weekly body mass index (BMI) and VAS, patients were characterized at baseline using the Eating Disorder Examination Questionnaire (EDE-Q), Eating Disorder Inventory (EDI), Symptom Check List 92 (SCL-92), Major Depression Inventory (MDI), and Autism Quotient (AQ). Results: The results showed a significant time effect, Wilks Lambda = 0.523, F = 3.12, p < 0.05 (power of 0.862), indicating a reduction in VAS scores of anxiety from baseline to week 8. There was no effect of baseline medication or scores of MDI on the results. BMI increased from a mean of 15.16 (week 1) to 17.35 (week 8). In comparison, patients dropping out after only three weeks (n = 31) also had a trend toward a reduction in VAS anxiety (ns). Conclusions: Inpatient weight restoration treatment is associated with a decrease in post-meal anxiety in AN, an effect that occurs early and becomes clinically significant in patients who stay in treatment.
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ISSN:2075-4426
2075-4426
DOI:10.3390/jpm11111079