Search Results - "Kizenko, Alena"
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The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
Published in Cell death & disease (05-06-2021)“…The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved…”
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Repeat Age Decomposition Informs an Ancient Set of Repeats Associated With Coleoid Cephalopod Divergence
Published in Frontiers in genetics (14-03-2022)“…In comparison with other molluscs and bilaterians, the genomes of coleoid cephalopods (squid, cuttlefish, and octopus) sequenced so far show remarkably…”
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The evolutionary history of Brachyury genes in Hydrozoa involves duplications, divergence, and neofunctionalization
Published in Scientific reports (09-06-2023)“…Brachyury, a member of T-box gene family, is widely known for its major role in mesoderm specification in bilaterians. It is also present in non-bilaterian…”
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The diversity of opsins in Lake Baikal amphipods (Amphipoda: Gammaridae)
Published in BMC ecology and evolution (10-05-2021)“…Vision is a crucial sense for the evolutionary success of many animal groups. Here we explore the diversity of visual pigments (opsins) in the transcriptomes…”
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The level of putative carotenoid-binding proteins determines the body color in two species of endemic Lake Baikal amphipods
Published in PeerJ (San Francisco, CA) (19-06-2020)“…Color is an essential clue for intra- and interspecies communication, playing a role in selection and speciation. Coloration can be based on nanostructures and…”
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Set7/9 controls proliferation and genotoxic drug resistance of NSCLC cells
Published in Biochemical and biophysical research communications (01-10-2021)“…The SET domain containing lysine-specific methyltransferase, Set7/9, covalently attaches methyl moieties to a variety of histone and non-histone substrates…”
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Regulation of autophagy flux by E3 ubiquitin ligase Pirh2 in lung cancer
Published in Biochemical and biophysical research communications (23-07-2021)“…Autophagy is a special catabolic cellular program that is induced in response to deprivation of nutrients and energy starvation. During the execution of this…”
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Attenuation of p53 mutant as an approach for treatment Her2-positive cancer
Published in Cell death discovery (10-10-2020)“…Breast cancer is one of the world’s leading causes of oncological disease-related death. It is characterized by a high degree of heterogeneity on the clinical,…”
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Nutlin sensitizes lung carcinoma cells to interferon-alpha treatment in MDM2-dependent but p53-independent manner
Published in Biochemical and biophysical research communications (01-01-2018)“…As an anticancer therapeutic, Interferon-alpha (IFNα) is used to treat a number of malignancies. However, the application of IFNα is restricted mostly due to…”
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