Search Results - "Kiyoshi, Hidekazu"

Discovery of a 1‑Methyl-3,4-dihydronaphthalene-Based Sphingosine-1-Phosphate (S1P) Receptor Agonist Ceralifimod (ONO-4641). A S1P1 and S1P5 Selective Agonist for the Treatment of Autoimmune Diseases by Kurata, Haruto, Kusumi, Kensuke, Otsuki, Kazuhiro, Suzuki, Ryo, Kurono, Masakuni, Komiya, Takaki, Hagiya, Hiroshi, Mizuno, Hirotaka, Shioya, Hiroki, Ono, Takeji, Takada, Yuka, Maeda, Tatsuo, Matsunaga, Norikazu, Kondo, Tetsu, Tominaga, Sachiko, Nunoya, Ken-ici, Kiyoshi, Hidekazu, Komeno, Masaharu, Nakade, Shinji, Habashita, Hiromu

“…The discovery of 1-({6-[(2-methoxy-4-propylbenzyl)­oxy]-1-methyl-3,4-dihydronaphthalen-2-yl}­methyl)­azetidine-3-carboxylic acid 13n (ceralifimod, ONO-4641), a…”
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Molecular and electrophysiological characteristics of K+ conductance sensitive to acidic pH in aortic smooth muscle cells of WKY and SHR by Kiyoshi, Hidekazu, Yamazaki, Daiju, Ohya, Susumu, Kitsukawa, Mika, Muraki, Katsuhiko, Saito, Shin-ya, Ohizumi, Yasushi, Imaizumi, Yuji

“…Changes in K(+) conductances and their contribution to membrane depolarization in the setting of an acidic pH environment have been studied in myocytes from…”
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Discovery of a 1-Methyl-3,4-dihydronaphthalene-Based Sphingosine-1-Phosphate (S1P) Receptor Agonist Ceralifimod (ONO-4641). A S1P 1 and S1P 5 Selective Agonist for the Treatment of Autoimmune Diseases by Kurata, Haruto, Kusumi, Kensuke, Otsuki, Kazuhiro, Suzuki, Ryo, Kurono, Masakuni, Komiya, Takaki, Hagiya, Hiroshi, Mizuno, Hirotaka, Shioya, Hiroki, Ono, Takeji, Takada, Yuka, Maeda, Tatsuo, Matsunaga, Norikazu, Kondo, Tetsu, Tominaga, Sachiko, Nunoya, Ken-Ici, Kiyoshi, Hidekazu, Komeno, Masaharu, Nakade, Shinji, Habashita, Hiromu

“…The discovery of 1-({6-[(2-methoxy-4-propylbenzyl)oxy]-1-methyl-3,4-dihydronaphthalen-2-yl}methyl)azetidine-3-carboxylic acid 13n (ceralifimod, ONO-4641), a…”
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Possible role of TASK in acidic pH induced depolarization in WKY and SHR aortic smooth muscle cells by Hidekazu Kiyoshi, Mika Kitsukawa, Shin-ya Saito, Susumu Ohya, Katsuhiko Muraki, Yasushi Ohizumi, Yuji Imaizumi

“…TASK (TWIK-related Acid-Sensitive K+ channel) belongs to 2 pore domain K+ channel family and is highly modulated by changes in extracellular pH. It has been…”
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