Search Results - "Kiyosawa, Hidenori"

Enhancing the neural differentiation capabilities of genetically asymmetric mouse F1 hybrid embryonic stem cell lines by SAITO, Ayaka, KATO, Hidemasa, KIYOSAWA, Hidenori

“…Allele-specific, monoallelic expression in diploid organisms represents an extreme case of allelic imbalance resulting from incompatibility between cis- and…”
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Monoallelic, antisense and total RNA transcription in an in vitro neural differentiation system based on F1 hybrid mice by Kondo, Shinji, Kato, Hidemasa, Suzuki, Yutaka, Takada, Toyoyuki, Eitoku, Masamitsu, Shiroishi, Toshihiko, Suganuma, Narufumi, Sugano, Sumio, Kiyosawa, Hidenori

“…We developed an system to differentiate embryonic stem cells (ESCs) derived from reciprocally crossed F1 hybrid mice into neurons, and used it to investigate…”
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Sequence and structure analysis of a mirror tRNA located upstream of the cytochrome oxidase I mRNA in mouse mitochondria by Okui, Saya, Ushida, Chisato, Kiyosawa, Hidenori, Kawai, Gota

“…RNA fragments corresponding to the mirror tRNA that is located upstream of the cytochrome oxidase I (COXI) gene in the mouse mitochondrial genome were found in…”
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Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression by Saito, Ayaka, Tahara, Ryosuke, Hirose, Michiko, Kadota, Masayo, Hasegawa, Ayumi, Kondo, Shinji, Kato, Hidemasa, Amano, Takanori, Yoshiki, Atsushi, Ogura, Atsuo, Kiyosawa, Hidenori

“…Allele-specific monoallelic gene expression is a unique phenomenon and a great resource for analyzing gene regulation. To study this phenomenon, we established…”
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Secondary structure-based analysis of mouse brain small RNA sequences obtained by using next-generation sequencing by Kiyosawa, Hidenori, Okumura, Akio, Okui, Saya, Ushida, Chisato, Kawai, Gota

“…In order to find novel structured small RNAs, next-generation sequencing was applied to small RNA fractions with lengths ranging from 40 to 140nt and secondary…”
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Regulation of Gene Expression by Sodium Valproate in Epithelial-to-Mesenchymal Transition by Noguchi, Shuhei, Eitoku, Masamitsu, Moriya, Shigeharu, Kondo, Shinji, Kiyosawa, Hidenori, Watanabe, Takashi, Suganuma, Narufumi

“…Purpose Epithelial-to-mesenchymal transition (EMT) is an important mechanism in cancer metastasis and pulmonary fibrosis. Previous studies demonstrated effect…”
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Comparison of two types of non-adherent plate for neuronal differentiation of mouse embryonic stem cells by Eitoku, Masamitsu, Suganuma, Narufumi, Kiyosawa, Hidenori

“…In vitro differentiation systems of mouse embryonic stem cells (ESCs) are widely used as tools for studies of cell differentiation, organogenesis, and…”
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Occupation exposed to road-traffic emissions and respiratory health among Congolese transit workers, particularly bus conductors, in Kinshasa: a cross-sectional study by Mbelambela, Etongola Papy, Hirota, Ryoji, Eitoku, Masamitsu, Muchanga, Sifa Marie Joelle, Kiyosawa, Hidenori, Yasumitsu-Lovell, Kahoko, Lawanga, Ontshick Leader, Suganuma, Narufumi

“…Road-traffic emissions (RTE) induce adverse health effects, notably respiratory symptoms and respiratory diseases, as a result of pollutants deposited into the…”
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Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice by Wada, Keiji, Saigoh, Kazumasa, Wang, Yu-Lai, Suh, Jun-Gyo, Yamanishi, Toshiyuki, Sakai, Yoshihisa, Kiyosawa, Hidenori, Harada, Takayuki, Ichihara, Nobutsune, Wakana, Shigeharu, Kikuchi, Tateki

“…The gracile axonal dystrophy (gad) mouse is an autosomal recessive mutant that shows sensory ataxia at an early stage, followed by motor ataxia at a later…”
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Identification of novel endogenous antisense transcripts by DNA microarray analysis targeting complementary strand of annotated genes by Numata, Koji, Osada, Yuko, Okada, Yuki, Saito, Rintaro, Hiraiwa, Noriko, Nakaoka, Hajime, Yamamoto, Naoyuki, Watanabe, Kazufumi, Okubo, Kazue, Kohama, Chihiro, Kanai, Akio, Abe, Kuniya, Kiyosawa, Hidenori

“…Recent transcriptomic analyses in mammals have uncovered the widespread occurrence of endogenous antisense transcripts, termed natural antisense transcripts…”
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Comparative analysis of cis-encoded antisense RNAs in eukaryotes by Numata, Koji, Okada, Yuki, Saito, Rintaro, Kiyosawa, Hidenori, Kanai, Akio, Tomita, Masaru

“…Recent large-scale transcriptomic analyses have identified numerous endogenously encoded cis-antisense RNAs that are thought to play important roles in diverse…”
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Expression analysis of box C/D snoRNAs with SNPs between C57BL/6 and MSM/Ms strains in male mouse by Saito, Rumiko, Otsu, Maina, Kiyosawa, Hidenori, Kawai, Gota

“…MSM/Ms mouse derived from the Japanese wild mouse has unique characteristics compared to the widely used C57BL/6 mouse. To examine the usefulness of the MSM/Ms…”
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Comprehensive expressional analyses of antisense transcripts in colon cancer tissues using artificial antisense probes by Saito, Rintaro, Kohno, Keisuke, Okada, Yuki, Osada, Yuko, Numata, Koji, Kohama, Chihiro, Watanabe, Kazufumi, Nakaoka, Hajime, Yamamoto, Naoyuki, Kanai, Akio, Yasue, Hiroshi, Murata, Soichiro, Abe, Kuniya, Tomita, Masaru, Ohkohchi, Nobuhiro, Kiyosawa, Hidenori

“…Recent studies have identified thousands of sense-antisense gene pairs across different genomes by computational mapping of cDNA sequences. These studies have…”
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Genome-wide impact of endogenous antisense transcripts in eukaryotes by Numata, Koji, Kiyosawa, Hidenori

“…Recent transcriptomic studies revealed that extensive proportions of genomes are transcribed, despite the limited fraction of protein-coding gene loci in the…”
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Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle by Machida, Masanao, Takeda, Kohei, Yokono, Hiroyuki, Ikemune, Sachiko, Taniguchi, Yuka, Kiyosawa, Hidenori, Takemasa, Tohru

“…Mammalian target of rapamycin (mTOR) pathway positively regulates the cell growth through ribosome biogenesis in many cell type. In general, myostatin is…”
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Fibrotic gene expression coexists with alveolar proteinosis in early indium lung by Noguchi, Shuhei, Eitoku, Masamitsu, Kiyosawa, Hidenori, Suganuma, Narufumi

“…Occupational inhalation of indium compounds can cause the so-called "indium lung disease". Most affected individuals show pulmonary alveolar proteinosis (PAP)…”
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Highly parallel SNP genotyping reveals high-resolution landscape of mono-allelic Ube3a expression associated with locus-wide antisense transcription by Numata, Koji, Kohama, Chihiro, Abe, Kuniya, Kiyosawa, Hidenori

“…We investigated the allele- and strand-specific transcriptional landscape of a megabase-wide genomic region of mouse Ube3a (ubiquitin protein ligase E3A) by…”
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Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma by Tojo, Michiko, Mori, Tetsuji, Kiyosawa, Hidenori, Honma, Yutaka, Tanno, Yoshihiro, Kanazawa, Ken-ya, Yokoya, Sachihiko, Kaneko, Fumio, Wanaka, Akio

“…In basal cell nevus syndrome (BCNS) patients, mutations of a gene, patched (ptc), which encodes a putative signal transducer of sonic hedgehog protein (SHH),…”
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Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression by SAITO, Ayaka, TAHARA, Ryosuke, HIROSE, Michiko, KADOTA, Masayo, HASEGAWA, Ayumi, KONDO, Shinji, KATO, Hidemasa, AMANO, Takanori, YOSHIKI, Atsushi, OGURA, Atsuo, KIYOSAWA, Hidenori

“…Allele-specific monoallelic gene expression is a unique phenomenon and a great resource for analyzing gene regulation. To study this phenomenon, we established…”
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Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue by Honma, Yutaka, Kanazawa, Ken-ya, Mori, Tetsuji, Tanno, Yoshihiro, Tojo, Michiko, Kiyosawa, Hidenori, Takeda, Junko, Nikaido, Takuya, Tsukamoto, Tetsuro, Yokoya, Sachihiko, Wanaka, Akio

“…Gliosis is a characteristic response of astrocytes to inflammation and trauma of the central nervous system (CNS). To study the mechanisms underlying gliosis,…”
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