Search Results - "Kivikko, M"
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Levosimendan meta-analyses: Is there a pattern in the effect on mortality?
Published in International journal of cardiology (15-04-2016)“…Abstract Background Levosimendan is an inodilator developed for treatment of acute heart failure and other cardiac conditions where the use of an inodilator is…”
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2
Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure
Published in European heart journal (01-03-2013)“…The aim of this study was to assess the prevalence of abnormal liver function tests (LFTs) and the associated clinical profile and outcome(s) in acute…”
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3
Levosimendan in Acute and Advanced Heart Failure: an Expert Perspective on Posology and Therapeutic Application
Published in Cardiovascular drugs and therapy (01-12-2018)“…Levosimendan, a calcium sensitizer and potassium channel-opener, is widely appreciated by many specialist heart failure practitioners for its effects on…”
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4
Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion
Published in International journal of cardiology (01-04-2015)“…Abstract In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines…”
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Levosimendan: current data, clinical use and future development
Published in Heart, lung and vessels (01-01-2013)“…Levosimendan is an inodilator indicated for the short-term treatment of acutely decompensated severe chronic heart failure, and in situations where…”
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Duration of the haemodynamic action of a 24-h infusion of levosimendan in patients with congestive heart failure
Published in European journal of heart failure (01-01-2007)“…Aims: To determine the duration of haemodynamic and neurohormonal action of a 24-h infusion of levosimendan in heart failure. Methods and results: This was a…”
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Repetitive use of levosimendan for treatment of chronic advanced heart failure: Clinical evidence, practical considerations, and perspectives: An expert panel consensus
Published in International journal of cardiology (15-06-2014)“…Abstract Background The intravenous inodilator levosimendan was developed for the treatment of patients with acutely decompensated heart failure. In the last…”
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Pharmaco-economics of levosimendan in cardiology: A European perspective
Published in International journal of cardiology (15-11-2015)“…Abstract Introduction Heart failure places a significant economic burden on health care. Acute heart failure requires hospitalization and often frequent…”
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9
Levosimendan: a new inodilatory drug for the treatment of decompensated heart failure
Published in Current pharmaceutical design (01-01-2005)“…Levosimendan is a new calcium sensitizer developed for the treatment of congestive heart failure. Experimental studies indicate that levosimendan increases…”
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10
Pharmacokinetics of levosimendan and its metabolites during and after a 24-hour continuous infusion in patients with severe heart failure
Published in International journal of clinical pharmacology and therapeutics (01-10-2002)“…Levosimendan is a new calcium sensitizer with additional vasodilatory properties developed for the short-term intravenous treatment of congestive heart…”
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Levosimendan beyond inotropy and acute heart failure: Evidence of pleiotropic effects on the heart and other organs: An expert panel position paper
Published in International journal of cardiology (01-11-2016)“…Abstract Levosimendan is a positive inotrope with vasodilating properties (inodilator) indicated for decompensated heart failure (HF) patients with low cardiac…”
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12
OP01-1 - Preoperative treatment with levosimendan in CABG surgery: data from the LEVO-CTS and LICORN studies
Published in Journal of cardiothoracic and vascular anesthesia (01-08-2018)Get full text
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Preoperative treatment with levosimendan in CABG surgery: data from the LEVO-CTS and LICORN studies
Published in Journal of cardiothoracic and vascular anesthesia (01-08-2018)Get full text
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14
Sustained hemodynamic effects of intravenous levosimendan
Published in Circulation (New York, N.Y.) (07-01-2003)“…The short-term infusion of levosimendan (Levo) improves hemodynamic function in patients with decompensated heart failure. The metabolites of Levo have a…”
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15
Cost Benefits Of Incorporating Levosimendan Into Cardiac Surgery Practice: German Base Case
Published in Value in health (01-11-2015)Get full text
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PCV93 - Cost Benefits Of Incorporating Levosimendan Into Cardiac Surgery Practice: German Base Case
Published in Value in health (01-11-2015)Get full text
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Oral Levosimendan Increases Cerebral Blood Flow Velocities in Patients with a History of Stroke or Transient Ischemic Attack: A Pilot Safety Study
Published in Current therapeutic research (01-12-2015)“…Abstract Background Intravenous levosimendan is indicated for acute heart failure. The compound has shown promising beneficial effects in ischemic stroke…”
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Renal Effects of Levosimendan: A Consensus Report
Published in Cardiovascular drugs and therapy (01-12-2013)“…Renal dysfunction is common in clinical settings in which cardiac function is compromised such as heart failure, cardiac surgery or sepsis, and is associated…”
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Pharmacodynamics and Safety of a New Calcium Sensitizer, Levosimendan, and Its Metabolites during an Extended Infusion in Patients with Severe Heart Failure
Published in Journal of clinical pharmacology (01-01-2002)“…Levosimendan is a new calcium sensitizer developed for the short‐term intravenous treatment of congestive heart failure. The aims of the present open‐label,…”
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Journal Article -
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Pharmacokinetics of levosimendan and its circulating metabolites in patients with heart failure after an extended continuous infusion of levosimendan
Published in British journal of clinical pharmacology (01-04-2004)“…Aims The purpose of the study was to characterize the pharmacokinetics of levosimendan and its metabolites OR‐1855 and OR‐1896 in patients with congestive…”
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