A correlation between renal morphology and renal circulation in pediatric nephrotic syndrome

A correlation between renal morphology and renal circulation in pediatric nephrotic syndrome

A morphometric analysis of the renal biopsy specimens and intrarenal hemodynamic study were performed in 37 pediatric patients with idiopathic nephrotic syndrome. The study indicated an inverse correlation between intrarenal hemodynamics (renal plasma flow and peritubular capillary flow) and a relat...

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Bibliographic Details
Published in:Renal failure Vol. 23; no. 1; p. 85
Main Authors: Yenrudi, S, Laohapaibul, A, Kittidiwit, W, Suteparuk, S, Futrakul, N
Format: Journal Article
Language:English
Published: England 01-01-2001
Subjects:
Biopsy
Child
Glomerular Filtration Rate
Glomerulosclerosis, Focal Segmental - pathology
Humans
Iodine Radioisotopes
Iodohippuric Acid
Kidney - diagnostic imaging
Kidney - pathology
Kidney Glomerulus - pathology
Nephrotic Syndrome - diagnostic imaging
Nephrotic Syndrome - pathology
Nephrotic Syndrome - physiopathology
Radionuclide Imaging
Radiopharmaceuticals
Renal Circulation
Technetium Tc 99m Pentetate
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Summary:A morphometric analysis of the renal biopsy specimens and intrarenal hemodynamic study were performed in 37 pediatric patients with idiopathic nephrotic syndrome. The study indicated an inverse correlation between intrarenal hemodynamics (renal plasma flow and peritubular capillary flow) and a relative area of renal cortical interstitium. In respect to the glomerular study, the incidence of glomerulosclerosis increased as the renal perfusion decreased, however, the correlation did not reach a statistical significance.
ISSN:0886-022X
DOI:10.1081/JDI-100001287