Search Results - "Kittel, J."
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The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation
Published in Cell reports (Cambridge) (12-05-2015)“…G-protein-coupled receptors (GPCRs) are typically regarded as chemosensors that control cellular states in response to soluble extracellular cues. However, the…”
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2
Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states
Published in Nature communications (18-08-2014)“…The precise molecular architecture of synaptic active zones (AZs) gives rise to different structural and functional AZ states that fundamentally shape chemical…”
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Channelrhodopsin-2–XXL, a powerful optogenetic tool for low-light applications
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2014)“…Channelrhodopsin-2 (ChR2) has provided a breakthrough for the optogenetic control of neuronal activity. In adult Drosophila melanogaster , however, its…”
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4
Effect of degraded environmental conditions on the service behavior of a X65 pipeline steel not designed for hydrogen transport
Published in International journal of hydrogen energy (02-01-2024)“…With the international drive to deploy green energies and decarbonized intermediates in the place of fossil fuel sources, a large number of developed countries…”
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Corrosion in CO2 Post-Combustion Capture with Alkanolamines – A Review
Published in Oil & gas science and technology (01-09-2014)“…CO2 capture and storage plays an important part in industrial strategies for the mitigation of greenhouse gas emissions. CO2 post-combustion capture with…”
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6
Homeostatic synaptic plasticity rescues neural coding reliability
Published in Nature communications (24-05-2023)“…To survive, animals must recognize reoccurring stimuli. This necessitates a reliable stimulus representation by the neural code. While synaptic transmission…”
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cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons
Published in Cell reports (Cambridge) (25-10-2016)“…The second messenger cyclic AMP (cAMP) plays an important role in synaptic plasticity. Although there is evidence for local control of synaptic transmission…”
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Maturation of active zone assembly by Drosophila Bruchpilot
Published in The Journal of cell biology (13-07-2009)“…Synaptic vesicles fuse at active zone (AZ) membranes where Ca²⁺ channels are clustered and that are typically decorated by electron-dense projections…”
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Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons
Published in eLife (08-08-2017)“…Adhesion-type G protein-coupled receptors (aGPCRs), a large molecule family with over 30 members in humans, operate in organ development, brain function and…”
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Active zone compaction correlates with presynaptic homeostatic potentiation
Published in Cell reports (Cambridge) (05-10-2021)“…Neurotransmitter release is stabilized by homeostatic plasticity. Presynaptic homeostatic potentiation (PHP) operates on timescales ranging from minute- to…”
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Bruchpilot Promotes Active Zone Assembly, Ca²⁺ Channel Clustering, and Vesicle Release
Published in Science (American Association for the Advancement of Science) (19-05-2006)“…The molecular organization of presynaptic active zones during calcium influx-triggered neurotransmitter release is the focus of intense investigation. The…”
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Drosophila active zones: From molecules to behaviour
Published in Neuroscience research (01-02-2018)“…•We review molecular mechanisms of active zone physiology in Drosophila.•The role of active zones is discussed in a behavioural context.•We focus on the NMJ,…”
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Corrosion mechanisms in aqueous solutions containing dissolved H2S. Part 1: Characterisation of H2S reduction on a 316L rotating disc electrode
Published in Corrosion science (01-01-2013)“…► Reduction reactions occurring during steel corrosion by CO2 and H2S are examined. ► H2S enhances the cathodic reactions in water similarly as CO2. ► CO2…”
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PACmn for improved optogenetic control of intracellular cAMP
Published in BMC biology (18-10-2021)“…Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic cells. The soluble…”
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15
Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition
Published in Frontiers in neuroscience (02-10-2018)“…Optogenetic manipulation of cells or living organisms became widely used in neuroscience following the introduction of the light-gated ion channel…”
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Hebbian Plasticity Guides Maturation of Glutamate Receptor Fields In Vivo
Published in Cell reports (Cambridge) (30-05-2013)“…Synaptic plasticity shapes the development of functional neural circuits and provides a basis for cellular models of learning and memory. Hebbian plasticity…”
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Synaptic Vesicle Proteins and Active Zone Plasticity
Published in Frontiers in synaptic neuroscience (2016)“…Neurotransmitter is released from synaptic vesicles at the highly specialized presynaptic active zone (AZ). The complex molecular architecture of AZs mediates…”
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Corrosion mechanisms in aqueous solutions containing dissolved H2S. Part 2: Model of the cathodic reactions on a 316L stainless steel rotating disc electrode
Published in Electrochimica acta (01-04-2014)“…In H2S containing solutions, the reduction of protons with a buffer effect contributing to the transport of protons at the steel surface, is not sufficient to…”
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Control of Adhesion GPCR Function Through Proteolytic Processing
Published in Handbook of experimental pharmacology (01-01-2016)“…Proteolytic processing events in adhesion GPCRs. aGPCRs can undergo multiple autoproteolytic (red asterisks) and proteolytic processing events by exogenous…”
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Antinociceptive modulation by the adhesion GPCR CIRL promotes mechanosensory signal discrimination
Published in eLife (30-09-2020)“…Adhesion-type GPCRs (aGPCRs) participate in a vast range of physiological processes. Their frequent association with mechanosensitive functions suggests that…”
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