Search Results - "Kittappa, Raja"

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age by Kittappa, Raja, Chang, Wendy W, Awatramani, Rajeshwar B, McKay, Ronald D G

“…Parkinson disease affects more than 1% of the population over 60 y old. The dominant models for Parkinson disease are based on the use of chemical toxins to…”
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Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools by Joksimovic, Milan, Anderegg, Angela, Roy, Anil, Campochiaro, Laura, Yun, Beth, Kittappa, Raja, McKay, Ronald, Awatramani, Rajeshwar

“…Midbrain dopamine neurons (mDA) are important regulators of diverse physiological functions, including movement, attention, and reward behaviors. Accordingly,…”
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Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis by Anderegg, Angela M, McKay, Ronald D G, Yun, Beth A, Awatramani, Rajeshwar B, Joksimovic, Milan, Taketo, Makoto M, Kittappa, Raja, Chang, Wendy W

“…The floor plate is not usually a neurogenic structure, but in the embryonic midbrain, dopaminergic neurons do develop from floor plate. This study shows that…”
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From stem cells to dopamine neurons: developmental biology meets neurodegeneration by Tailor, Jignesh, Andreska, Thomas, Kittappa, Raja

“…Neurodegenerative disease affects tens of millions of people, worldwide, and comes at a cost to the public of billions of dollars. Stem cell therapy, in recent…”
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Fibroblast Growth Factor 20 Polymorphisms and Haplotypes Strongly Influence Risk of Parkinson Disease by van der Walt, Joelle M., Noureddine, Maher A., Kittappa, Raja, Hauser, Michael A., Scott, William K., McKay, Ron, Zhang, Fengyu, Stajich, Jeffrey M., Fujiwara, Kenichiro, Scott, Burton L., Pericak-Vance, Margaret A., Vance, Jeffery M., Martin, Eden R.

“…The pathogenic process responsible for the loss of dopaminergic neurons within the substantia nigra of patients with Parkinson disease (PD) is poorly…”
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Will Stem Cell Biology Generate New Therapies for Parkinson's Disease? by McKay, Ron, Kittappa, Raja

“…Three papers recently published in Nature Medicine provide the most detailed analyses of fetal midbrain grafts in patients with Parkinson's disease. Some of…”
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Notch signalling regulates stem cell numbers in vitro and in vivo by McKay, Ronald D. G, Kittappa, Raja, Leker, Ronen R, Soldner, Frank, Poser, Steve W, Rueger, Maria A, Hoeppner, Daniel J, Ravin, Rea, Bae, Soo-Kyung, Androutsellis-Theotokis, Andreas

“…The hope of developing new transplantation therapies for degenerative diseases is limited by inefficient stem cell growth and immunological incompatibility…”
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Stem cells expanded from the human embryonic hindbrain stably retain regional specification and high neurogenic potency by Tailor, Jignesh, Kittappa, Raja, Leto, Ketty, Gates, Monte, Borel, Melodie, Paulsen, Ole, Spitzer, Sonia, Karadottir, Ragnhildur Thora, Rossi, Ferdinando, Falk, Anna, Smith, Austin

“…Stem cell lines that faithfully maintain the regional identity and developmental potency of progenitors in the human brain would create new opportunities in…”
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The Role of eNSCs in Neurodegenerative Disease by Kittappa, Raja, Bornstein, Stefan R., Androutsellis-Theotokis, Andreas

“…Recent progress in biology has shown that many if not all adult tissues contain a population of stem cells. It is believed that these cells are involved in the…”
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Genetic variation in FGF20 modulates hippocampal biology by Lemaitre, Herve, Mattay, Venkata S, Sambataro, Fabio, Verchinski, Beth, Straub, Richard E, Callicott, Joseph H, Kittappa, Raja, Hyde, Thomas M, Lipska, Barbara K, Kleinman, Joel E, McKay, Ronald, Weinberger, Daniel R

“…We explored the effect of single-nucleotide polymorphisms (SNPs) in the fibroblast growth factor 20 gene (FGF20) associated with risk for Parkinson's disease…”
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Plasticity, Niches, and the Use of Stem Cells by Tsai, Robert Y.L, Kittappa, Raja, McKay, Ronald D.G

“…Stem cells possess the ability to self-renew and generate multiple cell types of the tissues in which they reside. Several studies have reported…”
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The Molecular Characterization of the Fetal Stem Cell Marker AA4 by Petrenko, Oleksi, Beavis, Andrew, Klaine, Michele, Kittappa, Raja, Godin, Isabelle, Lemischka, Ihor R

“…We have identified and characterized the stem cell antigen AA4. This molecule is a type I transmembrane protein whose overall structure suggests a role in cell…”
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The floor plate gene, foxa2, is required for the generation and maintenance of midbrain dopamine neurons by Kittappa, Raja, Chang, Wendy W., Awatramani, Rajeshwar B., McKay, Ronald D.

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Provisional hypotheses for the molecular genetics of cognitive development: Imaging genetic pathways in the anterior cingulate cortex by Fossella, John, Fan, Jin, Liu, Xun, Guise, Kevin, Brocki, Karin, Hof, Patrick R., Kittappa, Raja, McKay, Ronald, Posner, Michael

“…Brain imaging genetic research involves a multitude of methods and spans many traditional levels of analysis. Given the vast permutations among several million…”
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Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis by Joksimovic, Milan, Yun, Beth A., Raja, Kittappa, Angela, Anderegg M., Wendy, Chang W., Makoto, Taketo M., McKay, Ronald D., Rajeshwar, Awatramani B.

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Provisional hypotheses for the molecular genetics of cognitive development : Imaging genetic pathways in the anterior cingulate cortex: Genetics and Imaging in Neuroscience by FOSSELLA, John, JIN FAN, XUN LIU, GUISE, Kevin, BROCKI, Karin, HOF, Patrick R, KITTAPPA, Raja, MCKAY, Ronald, POSNER, Michael

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Generating CNS neurons from embryonic, fetal, and adult stem cells by Kim, Jong-Hoon, Panchision, David, Kittappa, Raja, McKay, Ron

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Gene expression and the birth of progenitors which carry out regeneration in the newt and in the mouse by Kittappa, Raja

“…Regeneration is the reiteration of processes from embryonic development to repair or replace damaged or lost tissues or structures in an adult organisms…”
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A novel family of T-box genes in urodele amphibian limb development and regeneration: candidate genes involved in vertebrate forelimb/hindlimb patterning by Simon, H G, Kittappa, R, Khan, P A, Tsilfidis, C, Liversage, R A, Oppenheimer, S

“…In certain urodeles, a lost appendage, including hand and foot, can be completely replaced through epimorphic regeneration. The regeneration process involves…”
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Gene expression and the birth of progenitors which carry out regeneration in the newt and in the mouse by Kittappa, Raja

“…Regeneration is the reiteration of processes from embryonic development to repair or replace damaged or lost tissues or structures in an adult organisms…”
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