Search Results - "Kitt, Jay P."
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Adapting confocal Raman microscopy for in situ studies of redox transformations at electrode-electrolyte interfaces
Published in Journal of electroanalytical chemistry (Lausanne, Switzerland) (01-09-2021)“…Confocal Raman microscopy was applied to quantify redox species present within the diffusion layer adjacent to an electrode surface under potentiostatic…”
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2
Single Layer Graphene for Estimation of Axial Spatial Resolution in Confocal Raman Microscopy Depth Profiling
Published in Analytical chemistry (Washington) (02-01-2019)“…Single layer graphene (SLG), with its angstrom-scale thickness and strong Raman scattering cross section, was adapted for measurement of the axial…”
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Surface-Area Enhanced Raman Spectroscopy of DNA in Porous Silica: A Quantitative and Reproducible Alternative to Plasmonic-Based SERS
Published in Analytical chemistry (Washington) (14-05-2024)“…Despite the success of surface-enhanced Raman spectroscopy (SERS) for detecting DNA immobilized on plasmonic metal surfaces, its quantitative response is…”
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4
Raman Scattering Reveals Ion-Dependent G‑Quadruplex Formation in the 15-mer Thrombin-Binding Aptamer upon Association with α‑Thrombin
Published in Analytical chemistry (Washington) (07-11-2023)“…The discovery of DNA aptamers that bind biomolecular targets has enabled significant innovations in biosensing. Aptamers form secondary structures that exhibit…”
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Inter-Leaflet Phospholipid Exchange Impacts the Ligand Density Available for Protein Binding at Supported Lipid Bilayers
Published in Langmuir (07-06-2022)“…Phospholipid bilayers formed at solid–liquid interfaces have garnered interest as mimics of cell membranes to model association reactions of proteins with…”
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Confocal-Raman Microscopy Characterization of Supported Phospholipid Bilayers Deposited on the Interior Surfaces of Chromatographic Silica
Published in Journal of the American Chemical Society (21-03-2018)“…A common approach to exploring the structure and dynamics of biological membranes is through the deposition of model lipid bilayers on planar supports by…”
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Raman Spectroscopy Reveals Selective Interactions of Cytochrome c with Cardiolipin That Correlate with Membrane Permeability
Published in Journal of the American Chemical Society (15-03-2017)“…Permeabilization of the outer mitochondrial membrane is an integral step in apoptosis. The resulting release of pro-apoptotic signaling proteins leads to cell…”
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Raman Microscopy Investigation of GLP‑1 Peptide Association with Supported Phospholipid Bilayers
Published in Langmuir (14-12-2021)“…A wide range of important biological processes occur at phospholipid membranes including cell signaling, where a peptide or small molecule targets a…”
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Hybrid-Supported Bilayers Formed with Mixed-Charge Surfactants on C18-Functionalized Silica Surfaces
Published in Langmuir (07-07-2020)“…Mixtures of cationic–anionic surfactants have been shown to spontaneously form ordered monolayers at hydrophobic–hydrophilic boundaries, including air–water…”
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Hybrid-Supported Bilayers Formed with Mixed-Charge Surfactants on C 18 -Functionalized Silica Surfaces
Published in Langmuir (07-07-2020)“…Mixtures of cationic-anionic surfactants have been shown to spontaneously form ordered monolayers at hydrophobic-hydrophilic boundaries, including air-water…”
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Confocal Raman Microscopy for Label-Free Detection of Protein–Ligand Binding at Nanopore-Supported Phospholipid Bilayers
Published in Analytical chemistry (Washington) (02-10-2018)“…Interactions of lectins, proteins that selectively bind carbohydrates, play an important role in many biological processes including cell adhesion, immune…”
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Structural Elucidation of Bisulfite Adducts to Pseudouridine That Result in Deletion Signatures during Reverse Transcription of RNA
Published in Journal of the American Chemical Society (16-10-2019)“…The recent report of RBS-Seq to map simultaneously the epitranscriptomic modifications N 1-methyladenosine, 5-methylcytosine, and pseudouridine (Ψ) via…”
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13
Interdisciplinary data science to advance environmental health research and improve birth outcomes
Published in Environmental research (01-06-2021)“…Rates of preterm birth and low birthweight continue to rise in the United States and pose a significant public health problem. Although a variety of…”
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Hybrid-Lipid Bilayers Induce n‑Alkyl-Chain Order in Reversed-Phase Chromatographic Surfaces, Impacting their Shape Selectivity for Aromatic Hydrocarbon Partitioning
Published in Analytical chemistry (Washington) (02-03-2021)“…Shape selectivity is important in reversed-phase liquid chromatographic separations, where stationary phases are capable of separating geometric isomers,…”
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Confocal Raman Microscopy of Hybrid-Supported Phospholipid Bilayers within Individual C18-Functionalized Chromatographic Particles
Published in Langmuir (06-09-2016)“…Measuring lipid-membrane partitioning of small molecules is critical to predicting bioavailability and investigating molecule–membrane interactions. A stable…”
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Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles
Published in Langmuir (21-04-2020)“…Phospholipid bilayers deposited on a variety of surfaces provide models for investigation of the lipid membrane structure and supports for biocompatible…”
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Confocal Raman Microscopy for in Situ Measurement of Octanol–Water Partitioning within the Pores of Individual C18-Functionalized Chromatographic Particles
Published in Analytical chemistry (Washington) (19-05-2015)“…Octanol–water partitioning is one of the most widely used predictors of hydrophobicity and lipophilicity. Traditional methods for measuring octanol–water…”
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Confocal Raman Microscopy for in Situ Measurement of Phospholipid–Water Partitioning into Model Phospholipid Bilayers within Individual Chromatographic Particles
Published in Analytical chemistry (Washington) (05-06-2018)“…The phospholipid–water partition coefficient is a commonly measured parameter that correlates with drug efficacy, small-molecule toxicity, and accumulation of…”
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Confocal Raman Microscopy for in Situ Detection of Solid-Phase Extraction of Pyrene into Single C18–Silica Particles
Published in Analytical chemistry (Washington) (04-02-2014)“…Solid-phase extraction (SPE) is a well-known method for separating and preconcentrating analytes prior to ex situ detection and quantification. Despite…”
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20
Vibrational Spectroscopic Monitoring of the Gelation Transition in Nafion Ionomer Dispersions
Published in Applied spectroscopy (01-04-2021)“…Infrared and Raman spectroscopy techniques were applied to investigate the drying and aggregation behavior of Nafion ionomer particles dispersed in aqueous…”
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