Search Results - "Kitchen, Mark"

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    Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer by Kitchen, Mark O, Bryan, Richard T, Haworth, Kim E, Emes, Richard D, Luscombe, Christopher, Gommersall, Lyndon, Cheng, K K, Zeegers, Maurice P, James, Nicholas D, Devall, Adam J, Fryer, Anthony A, Farrell, William E

    Published in PloS one (02-09-2015)
    “…Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous…”
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    Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies by Wu, Pensee, Farrell, William E, Haworth, Kim E, Emes, Richard D, Kitchen, Mark O, Glossop, John R, Hanna, Fahmy W, Fryer, Anthony A

    Published in Epigenetics (01-02-2018)
    “…Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were…”
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    Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies by Unsworth-White, Samantha R, Kitchen, Mark O, Bryan, Richard T

    Published in Future oncology (London, England) (01-01-2022)
    “…Supplies of intravesical Bacillus Calmette-Guérin (BCG), the first-line treatment for most intermediate- and high-risk non-muscle-invasive bladder cancers…”
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    Physoxia Influences Global and Gene-Specific Methylation in Pluripotent Stem Cells by Dogan, Fatma, Aljumaily, Rakad M Kh, Kitchen, Mark, Forsyth, Nicholas R

    “…Pluripotent stem cells (PSC) possess unlimited proliferation, self-renewal, and a differentiation capacity spanning all germ layers. Appropriate culture…”
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    Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning by Ward, Kelly, Kitchen, Mark O, Mathias, Suresh-Jay, Khanim, Farhat L, Bryan, Richard T.

    Published in Frontiers in surgery (26-07-2022)
    “…Introduction Non-muscle-invasive bladder cancer (NMIBC) is a common and heterogeneous disease; many patients develop recurrent or progress to muscle-invasive…”
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    Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer by Kitchen, Mark O., Bryan, Richard T., Emes, Richard D., Glossop, John R., Luscombe, Christopher, Cheng, K. K., Zeegers, Maurice P., James, Nicholas D., Devall, Adam J., Mein, Charles A., Gommersall, Lyndon, Fryer, Anthony A., Farrell, William E.

    Published in Epigenetics (03-03-2016)
    “…High-grade non-muscle invasive bladder cancer (HG-NMIBC) is a clinically unpredictable disease with greater risks of recurrence and progression relative to…”
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    DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells by Dogan, Fatma, Aljumaily, Rakad M Kh, Kitchen, Mark, Forsyth, Nicholas R

    Published in Cells (Basel, Switzerland) (27-04-2021)
    “…The application of physiological oxygen (physoxia) concentrations is becoming increasingly commonplace within a mammalian stem cell culture. Human mesenchymal…”
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    Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells by Fadayomi, Idowu, Sari, Suat, Kitchen, Mark, Reynisson, Jóhannes, Forsyth, Nicholas, Li, Wen-Wu

    “…Inappropriate DNA methylation of tumour suppressor genes can affect their expression and function, and as such, DNA methylation has been a promising target for…”
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    Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells by Kitchen, Mark O., Yacqub-Usman, Kiren, Emes, Richard D., Richardson, Alan, Clayton, Richard N., Farrell, William E.

    Published in Pituitary (01-10-2015)
    “…Introduction Transgenic mice overexpressing the high mobility group A ( HMGA ) genes, Hmga1 or Hmga2 develop pituitary tumours and their overexpression is also…”
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    Medium-term outcomes of patients with insulin-dependent diabetes after laparoscopic adjustable gastric banding by Singhal, Rishi, M.R.C.S, Ahmed, Missba, M.B.Ch.B, Krempic, Avril, M.B.Ch.B, Kitchen, Mark, M.B.Ch.B, Super, Paul, F.R.C.S

    “…Abstract Background Bariatric surgery is effective in the control of type 2 diabetes mellitus. Laparoscopic adjustable gastric banding is a popular form of…”
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    Facilitating small groups: how to encourage student learning by Kitchen, Mark

    Published in The clinical teacher (01-02-2012)
    “…Summary Background:  Many clinicians are involved in medical education, with small group teaching (SGT) forming a significant part of their work. Most…”
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    Junior doctors' guide to portfolio learning and building by Kitchen, Mark

    Published in The clinical teacher (01-10-2012)
    “…Summary Background:  A portfolio is a collection of evidence supporting an individual’s achievement of competencies and learning outcomes. The material…”
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    Band slippage and erosion after laparoscopic gastric banding: a meta-analysis by Singhal, Rishi, Bryant, Catherine, Kitchen, Mark, Khan, Khalid S., Deeks, Jon, Guo, Boliang, Super, Paul

    Published in Surgical endoscopy (01-12-2010)
    “…Background Laparoscopic adjustable gastric banding has the lowest morbidity and mortality rates among the common bariatric procedures. Troublesome…”
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    Metabolic Outcomes of Obese Diabetic Patients Following Laparoscopic Adjustable Gastric Banding by Singhal, Rishi, Kitchen, Mark, Bridgwater, Sue, Super, Paul

    Published in Obesity surgery (01-11-2008)
    “…Introduction Obesity is an independent risk factor in the development of diabetes. Weight loss surgery is the most effective treatment of morbid obesity. This…”
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