Search Results - "Kitchen, Mark"
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Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer
Published in PloS one (02-09-2015)“…Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous…”
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Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies
Published in Epigenetics (01-02-2018)“…Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were…”
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Immunotherapy for non-muscle-invasive bladder cancer: from the origins of BCG to novel therapies
Published in Future oncology (London, England) (01-01-2022)“…Supplies of intravesical Bacillus Calmette-Guérin (BCG), the first-line treatment for most intermediate- and high-risk non-muscle-invasive bladder cancers…”
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Physoxia Influences Global and Gene-Specific Methylation in Pluripotent Stem Cells
Published in International journal of molecular sciences (23-05-2022)“…Pluripotent stem cells (PSC) possess unlimited proliferation, self-renewal, and a differentiation capacity spanning all germ layers. Appropriate culture…”
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Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning
Published in Frontiers in surgery (26-07-2022)“…Introduction Non-muscle-invasive bladder cancer (NMIBC) is a common and heterogeneous disease; many patients develop recurrent or progress to muscle-invasive…”
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Validation of Space-Based Albedo Products from Upscaled Tower-Based Measurements Over Heterogeneous and Homogeneous Landscapes
Published in Remote sensing (Basel, Switzerland) (01-03-2020)“…Surface albedo is a fundamental radiative parameter as it controls the Earth’s energy budget and directly affects the Earth’s climate. Satellite observations…”
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Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer
Published in Epigenetics (03-03-2016)“…High-grade non-muscle invasive bladder cancer (HG-NMIBC) is a clinically unpredictable disease with greater risks of recurrence and progression relative to…”
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DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells
Published in Cells (Basel, Switzerland) (27-04-2021)“…The application of physiological oxygen (physoxia) concentrations is becoming increasingly commonplace within a mammalian stem cell culture. Human mesenchymal…”
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HaEmaturia After Transurethral resection of bladder Tumour (HEATT): A multicentre, regional collaborative analysis of factors associated with emergency re-admission with haematuria following TURBT
Published in Journal of clinical urology (07-08-2023)“…Objective: To calculate the re-admission rate with haematuria within 30 days of elective transurethral resection of bladder tumour (TURBT), and identify…”
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Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells
Published in Pharmacological research. Modern Chinese medicine (01-06-2022)“…Inappropriate DNA methylation of tumour suppressor genes can affect their expression and function, and as such, DNA methylation has been a promising target for…”
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Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells
Published in Pituitary (01-10-2015)“…Introduction Transgenic mice overexpressing the high mobility group A ( HMGA ) genes, Hmga1 or Hmga2 develop pituitary tumours and their overexpression is also…”
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Medium-term outcomes of patients with insulin-dependent diabetes after laparoscopic adjustable gastric banding
Published in Surgery for obesity and related diseases (2013)“…Abstract Background Bariatric surgery is effective in the control of type 2 diabetes mellitus. Laparoscopic adjustable gastric banding is a popular form of…”
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Wait times for Patients with Bladder Cancer from Trans-Urethral Resection of Bladder Tumour to Cystectomy or Chemoradiotherapy
Published in European journal of surgical oncology (01-01-2024)Get full text
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Facilitating small groups: how to encourage student learning
Published in The clinical teacher (01-02-2012)“…Summary Background: Many clinicians are involved in medical education, with small group teaching (SGT) forming a significant part of their work. Most…”
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P59
Published in Surgery for obesity and related diseases (01-05-2007)Get full text
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P56
Published in Surgery for obesity and related diseases (01-05-2007)Get full text
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Junior doctors' guide to portfolio learning and building
Published in The clinical teacher (01-10-2012)“…Summary Background: A portfolio is a collection of evidence supporting an individual’s achievement of competencies and learning outcomes. The material…”
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Band slippage and erosion after laparoscopic gastric banding: a meta-analysis
Published in Surgical endoscopy (01-12-2010)“…Background Laparoscopic adjustable gastric banding has the lowest morbidity and mortality rates among the common bariatric procedures. Troublesome…”
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Metabolic Outcomes of Obese Diabetic Patients Following Laparoscopic Adjustable Gastric Banding
Published in Obesity surgery (01-11-2008)“…Introduction Obesity is an independent risk factor in the development of diabetes. Weight loss surgery is the most effective treatment of morbid obesity. This…”
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