Search Results - "Kitayama, Tetsuya"

Glucose-independent renoprotective mechanisms of the tissue dipeptidyl peptidase-4 inhibitor, saxagliptin, in Dahl salt-sensitive hypertensive rats by Uchii, Masako, Kimoto, Naoya, Sakai, Mariko, Kitayama, Tetsuya, Kunori, Shunji

“…Although previous studies have shown an important role of renal dipeptidyl peptidase-4 (DPP-4) inhibition in ameliorating kidney injury in hypertensive rats,…”
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Evocalcet prevents ectopic calcification and parathyroid hyperplasia in rats with secondary hyperparathyroidism by Sakai, Mariko, Tokunaga, Shin, Kawai, Mika, Murai, Miki, Kobayashi, Misaki, Kitayama, Tetsuya, Saeki, Satoshi, Kawata, Takehisa

“…Elevated parathyroid hormone (PTH) levels in secondary hyperparathyroidism (SHPT) lead to vascular calcification, which is associated with cardiovascular…”
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Cardiac DPP-4 inhibition by saxagliptin ameliorates isoproterenol-induced myocardial remodeling and cardiac diastolic dysfunction in rats by Ikeda, Junichi, Kimoto, Naoya, Kitayama, Tetsuya, Kunori, Shunji

“…Saxagliptin, a potent and selective DPP-4 inhibitor, is characterized by its slow dissociation from DPP-4 and its long half-life and is expected to have a…”
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The persistent inhibitory properties of saxagliptin on renal dipeptidyl peptidase-4: Studies with HK-2 cells in vitro and normal rats in vivo by Uchii, Masako, Sakai, Mariko, Hotta, Yuhei, Saeki, Satoshi, Kimoto, Naoya, Hamaguchi, Akinori, Kitayama, Tetsuya, Kunori, Shunji

“…Saxagliptin, a potent and selective DPP-4 inhibitor, exhibits a slow dissociation from DPP-4. We investigated the sustained effects of saxagliptin on renal…”
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Ultra-Broadband Silicon-Wire Polarization Beam Combiner/Splitter Based on a Wavelength Insensitive Coupler With a Point-Symmetrical Configuration by Uematsu, Takui, Kitayama, Tetsuya, Ishizaka, Yuhei, Saitoh, Kunimasa

“…An ultrabroadband silicon wire polarization beam combiner/splitter (PBCS) based on a wavelength-insensitive coupler is proposed. The proposed PBCS consists of…”
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QT PRODACT: In Vivo QT Assay in the Conscious Dog for Assessing the Potential for QT Interval Prolongation by Human Pharmaceuticals by Toyoshima, Shigeki, Kanno, Akihiro, Kitayama, Tetsuya, Sekiya, Koji, Nakai, Keiko, Haruna, Masao, Mino, Terumasa, Miyazaki, Hiroyasu, Yano, Koji, Yamamoto, Keiji

“…The goal of the present study was to examine the utility of the conscious dog model by assessing the QT-interval-prolonging potential of ten positive compounds…”
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QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation by Ando, Kentaro, Hombo, Toshiyasu, Kanno, Akihiro, Ikeda, Hironobu, Imaizumi, Masakazu, Shimizu, Noritsugu, Sakamoto, Kengo, Kitani, Shin-ichi, Yamamoto, Yoshinori, Hizume, Shingo, Nakai, Keiko, Kitayama, Tetsuya, Yamamoto, Keiji

“…In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys…”
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QT PRODACT: Sensitivity and Specificity of the Canine Telemetry Assay for Detecting Drug-Induced QT Interval Prolongation by Miyazaki, Hiroyasu, Watanabe, Hiroyuki, Kitayama, Tetsuya, Nishida, Masahiro, Nishi, Yasuhiro, Sekiya, Koji, Suganami, Hideki, Yamamoto, Keiji

“…The purpose of this investigation was to define the sensitivity and specificity of the canine telemetry assay for detecting drug-induced QT interval…”
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新型コロナウイルス感染症による外出自粛された通所サービス利用者への理学療法士による運動指導の効果: 後方視的研究による検討 by 大沼, 亮, 松田, 雅弘, 早乙女, 雄紀, 中嶋, 一歩, 山﨑, 達之, 北山, 哲也, ネルソン, 祥子

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Effects of evocalcet on parathyroid calcium‐sensing receptor and vitamin D receptor expression in uremic rats by Saito, Tomohiro, Mizobuchi, Masahide, Sakai, Mariko, Kawata, Takehisa, Kitayama, Tetsuya, Kato, Tadashi, Suzuki, Taihei, Ogata, Hiroaki, Koiwa, Fumihiko, Honda, Hirokazu

“…Little is known about the effect of the recently developed calcimimetic evocalcet (Evo) on parathyroid calcium‐sensing receptor (CaSR) and vitamin D receptor…”
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Effect of Evocalcet on Parathyroid Calcium-Sensing Receptor and Vitamin D Receptor Expressions in Uremic Rats: TH-PO143 by Saito, Tomohiro, Mizobuchi, Masahide, Sakai, Mariko, Kawata, Takehisa, Kitayama, Tetsuya, Kato, Tadashi, Suzuki, Taihei, Ogata, Hiroaki, Koiwa, Fumihiko, Honda, Hirokazu

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Critical role of renal dipeptidyl peptidase-4 in ameliorating kidney injury induced by saxagliptin in Dahl salt-sensitive hypertensive rats by Sakai, Mariko, Uchii, Masako, Myojo, Kensuke, Kitayama, Tetsuya, Kunori, Shunji

“…Saxagliptin, a potent dipeptidyl peptidase-4 (DPP-4) inhibitor, is currently used to treat type 2 diabetes mellitus, and it has been reported to exhibit a…”
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Effect of Exercise Guidance for Day Care Service Users Refraining from Going Out due to COVID-19 Provided by a Physical Therapist: A Retrospective Study: 後方視的研究による検討 by ONUMA, Ryo, MATSUDA, Tadamitsu, SOUTOME, Yuki, NAKAJIMA, Kazuho, YAMAZAKI, Tatsuyuki, KITAYAMA, Tetsuya, NELSON, Sachiko

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The L-, N-, and T-type triple calcium channel blocker benidipine acts as an antagonist of mineralocorticoid receptor, a member of nuclear receptor family by Kosaka, Hiromichi, Hirayama, Kazunori, Yoda, Nobuyuki, Sasaki, Katsutoshi, Kitayama, Tetsuya, Kusaka, Hideaki, Matsubara, Masahiro

“…Aldosterone-induced activation of mineralocorticoid receptor, a member of the nuclear receptor family, results in increased tissue damage such as vascular…”
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Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R by Akizuki, Osamu, Inayoshi, Atsushi, Kitayama, Tetsuya, Yao, Kozo, Shirakura, Shiro, Sasaki, Katsutoshi, Kusaka, Hideaki, Matsubara, Masahiro

“…Benidipine, a long-lasting dihydropyridine calcium channel blocker, is used for treatment of hypertension and angina. Benidipine exerts pleiotropic…”
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Effect of Exercise Guidance for Day Care Service Users Refraining from Going Out due to COVID-19 Provided by a Physical Therapist: A Retrospective Study by ONUMA, Ryo, MATSUDA, Tadamitsu, SOUTOME, Yuki, NAKAJIMA, Kazuho, YAMAZAKI, Tatsuyuki, KITAYAMA, Tetsuya, NELSON, Sachiko

“…[Purpose] To clarify the effect of exercise guidance for day care service users refraining from going out (self-restraint) due to infection with the new…”
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Evaluation of effects on cardiac contractility in conscious common marmosets using telemetry by Kitayama, Tetsuya, Saito, Takashi, Kajihara, Masatomo, Harada, Katsuhiko

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Blood supply of the sinus node artery in beagle dogs by IZUMISAWA, N, MACHIDA, N, KIRYU, K, KITAYAMA, T, NAKAMURA, T, SUZUKI, T

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Measurement of Cardio-hemodynamic Data in Conscious Dogs by a Radiotelemetry System by Kitayama, Tetsuya, Imabeppu, Susumu, Sano, Tomoyuki, Saeki, Koji, Hara, Takuji

“…A radiotelemetry transmitter (TL11M3-D70-PCP, Data Science, Inc., USA) was used for continuous measurement of cardiohemodynamic data in conscious and…”
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