Search Results - "Kitayama, Michio"

Time Taken for and Causes of a Decline to Hoehn and Yahr Stage 5 in Patients with Parkinson's Disease by Kashihara, Kenichi, Kitayama, Michio

“…Objective Prediction of time until and causes of becoming bedridden may help patients with Parkinson's disease (PD) plan their productive lives. This study…”
Get full text

Prevalence of progressive supranuclear palsy in Yonago: change throughout a decade by Takigawa, Hiroshi, Kitayama, Michio, Wada‐Isoe, Kenji, Kowa, Hisanori, Nakashima, Kenji

“…Background Progressive supranuclear palsy (PSP) is a neurodegenerative disorder that is sometimes confused with Parkinson's disease, multiple system atrophy,…”
Get full text

Autopsy case of spinocerebellar ataxia type 31 with severe dementia at the terminal stage by Adachi, Tadashi, Kitayama, Michio, Nakano, Toshiya, Adachi, Yoshiki, Kato, Shinsuke, Nakashima, Kenji

“…Spinocerebellar ataxia type 31 (SCA31) is an autosomal dominant cerebellar ataxia commonly observed in Japan. However, few neuropathological examinations have…”
Get full text

Gene expression analysis of the murine model of amyotrophic lateral sclerosis: Studies of the Leu126delTT mutation in SOD1 by Fukada, Yasuyo, Yasui, Kenichi, Kitayama, Michio, Doi, Koji, Nakano, Toshiya, Watanabe, Yasuhiro, Nakashima, Kenji

“…Abstract The pathogenic events that lead to amyotrophic lateral sclerosis (ALS) have not been elucidated. We previously described familial amyotrophic lateral…”
Get full text

Improvement in delusions and hallucinations in patients with dementia with Lewy bodies upon administration of yokukansan, a traditional Japanese medicine by IWASAKI, Koh, KOSAKA, Kenji, MORI, Hideo, OKITSU, Reina, FURUKAWA, Katsutoshi, MANABE, Yuta, YOSHITA, Mitsuhiro, KANAMORI, Aya, ITO, Nobuo, WADA, Kenji, KITAYAMA, Michio, HORIGUCHI, Jun, YAMAGUCHI, Shuhei, TAKAYAMA, Shin, FUKUHARA, Ryuji, OUMA, Shinji, NAKANO, Seigo, HASHIMOTO, Mamoru, KINOSHITA, Toru

“…Background:  This multicentre open‐label trial examined the efficacy and safety of the traditional Japanese medicine, or Kampo medicine, yokukansan (YKS), for…”
Get full text

Prevalence of dementia in the rural island town of Ama-cho, Japan by Wada-Isoe, Kenji, Uemura, Yusuke, Suto, Yutaka, Doi, Koji, Imamura, Keiko, Hayashi, Ai, Kitayama, Michio, Watanabe, Yasuhiro, Adachi, Yoshiki, Nakashima, Kenji

“…With the striking increase in the number of elderly people in Japan, dementia has not only become a medical but also a social issue. We studied the prevalence…”
Get more information

Multidetector Computed Tomography Angiography to Detect the Cause of Multiple Brain Infarctions by Kawada, Sanami, MD, Hamaguchi, Toshikazu, MD, Kitayama, Michio, MD, Imamura, Takaki, MD, Ohno, Manabu, MD, Kashihara, Kenichi, MD, Iwasaki, Kouichiro, MD

“…Background Multidetector computed tomography angiography (MDCTA) is useful to inspect cardiovascular pathologic changes with minimal invasiveness. Here we…”
Get full text

Adherent monomer-misfolded SOD1 by Watanabe, Yasuhiro, Morita, Eri, Fukada, Yasuyo, Doi, Koji, Yasui, Kenichi, Kitayama, Michio, Nakano, Toshiya, Nakashima, Kenji

“…Multiple cellular functions are compromised in amyotrophic lateral sclerosis (ALS). In familial ALS (FALS) with Cu/Zn superoxide dismutase (SOD1) mutations,…”
Get full text

Time Taken for and Causes of a Decline to Hoehn and Yahr Stage 5 in Patients with Parkinson's Disease by Kashihara, Kenichi, Kitayama, Michio

“…Objective Prediction of time until and causes of becoming bedridden may help patients with Parkinson's disease (PD) plan their productive lives. This study…”
Get full text

Relationship between 123I-MIBG scintigrams and REM sleep behavior disorder in Parkinson’s disease by Nomura, Takashi, Inoue, Yuichi, Högl, Birgit, Uemura, Yusuke, Kitayama, Michio, Abe, Takashi, Miyoshi, Hidenao, Nakashima, Kenji

“…Uptake of 123I-labeled meta-iodobenzylguanidine (MIBG) in myocardial scintigrams has been shown to be as low in patients with idiopathic RBD as in Parkinson’s…”
Get full text

Co-induction of heme oxygenase-1 and peroxiredoxin I in astrocytes and microglia around hemorrhagic region in the rat brain by Nakaso, Kazuhiro, Kitayama, Michio, Mizuta, Einosuke, Fukuda, Hiroki, Ishii, Tetsuro, Nakashima, Kenji, Yamada, Kazuo

“…Heme[none1] oxygenase-1 (HO-1) and peroxiredoxin I (PrxI) are known to be oxidative stress- and heme-related proteins. The antioxidant activity of PrxI is…”
Get full text

Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice by Doi, Koji, Nakano, Toshiya, Kitayama, Michio, Watanabe, Yasuhiro, Yasui, Kenichi, Fukada, Yasuyo, Morino, Shinichi, Kaidoh, Toshiyuki, Nakashima, Kenji, Inoué, Takao

“…We investigated the time course of ultrastructural changes of mitochondria in the spinal cord of homozygotes of Leu126TTdel SOD1 (superoxide dismutase 1) with…”
Get full text

Induction of Heme Oxygenase-1 in the Rat Brain by Kainic Acid-Mediated Excitotoxicity: The Dissociation of mRNA and Protein Expression in Hippocampus by Nakaso, Kazuhiro, Kitayama, Michio, Kimura, Koji, Yanagawa, Toru, Ohama, Eisaku, Nakashima, Kenji, Ishii, Tetsuro, Yamada, Kazuo

“…Heme oxygenase-1 (HO-1) is induced under various stresses. Here we report the induction and localization of HO-1 in the rat brain by intraperitoneal…”
Get full text

Relationship between (123)I-MIBG scintigrams and REM sleep behavior disorder in Parkinson's disease by Nomura, Takashi, Inoue, Yuichi, Högl, Birgit, Uemura, Yusuke, Kitayama, Michio, Abe, Takashi, Miyoshi, Hidenao, Nakashima, Kenji

“…Uptake of (123)I-labeled meta-iodobenzylguanidine (MIBG) in myocardial scintigrams has been shown to be as low in patients with idiopathic RBD as in…”
Get full text

Randomized controlled trial of KW-6356 monotherapy in patients with early untreated Parkinson's disease by Maeda, Tetsuya, Kimura, Takashi, Sugiyama, Kenichiro, Yamada, Kana, Hiraiwa, Ren, Nishi, Masato, Hattori, Nobutaka

“…KW-6356 is a novel selective adenosine A receptor antagonist/inverse agonist. We evaluated the efficacy and safety of KW-6356 as monotherapy in patients with…”
Get full text

Diagnostic markers for diagnosing dementia with Lewy bodies: CSF and MIBG cardiac scintigraphy study by Wada-Isoe, Kenji, Kitayama, Michio, Nakaso, Kazuhiro, Nakashima, Kenji

“…Abstract Objective This study examined the diagnostic value of cerebrospinal fluid (CSF) markers and iodine-123 metaiodobenzylguanidine (123 I-MIBG) cardiac…”
Get full text

A novel cell transplantation protocol and its application to an ALS mouse model by Morita, Eri, Watanabe, Yasuhiro, Ishimoto, Miho, Nakano, Toshiya, Kitayama, Michio, Yasui, Kenichi, Fukada, Yasuyo, Doi, Koji, Karunaratne, Asanka, Murrell, Wayne G, Sutharsan, Ratneswary, Mackay-Sim, Alan, Hata, Yoshio, Nakashima, Kenji

“…Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease, which selectively affects motor neurons throughout the central nervous system. The…”
Get full text

Association of visual hallucinations with reduction of MIBG cardiac uptake in Parkinson's disease by Kitayama, Michio, Wada-Isoe, Kenji, Irizawa, Yoshito, Nakashima, Kenji

“…Abstract Background Postganglionic cardiac sympathetic denervation is evident in patients with Parkinson’s disease (PD) and iodine-123 metaiodobenzylguanidine…”
Get full text

Autopsy-confirmed progressive supranuclear palsy with decreased uptake of metaiodobenzylguanidine by Adachi, Tadashi, Kitayama, Michio, Wada-Isoe, Kenji, Nakano, Toshiya, Nakashima, Kenji

“…Microscopy showed neuronal loss and gliosis were severe in the globus pallidus, subthalamic nucleus, substantia nigra, dentate nucleus, and inferior olivary…”
Get full text

OPEN LABEL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF YOKUKANSAN, A TRADITIONAL ASIAN MEDICINE, IN DEMENTIA WITH LEWY BODIES by Iwasaki, Koh, Kosaka, Kenji, Mori, Hideo, Okitsu, Reina, Furukawa, Katsutoshi, Manabe, Yuta, Yoshita, Mitsuhiro, Kanamori, Aya, Ito, Nobuo, Wada, Kenji, Kitayama, Michio, Horiguchi, Jun, Yamaguchi, Shuhei, Fukuhara, Ryuji, Ouma, Shinji, Nakano, Seigo, Hashimoto, Mamoru, Kinoshita, Toru

Get full text