Search Results - "Kitanaga, Yukihiro"

Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System by Kubo, Satoshi, Nakayamada, Shingo, Sakata, Kei, Kitanaga, Yukihiro, Ma, Xiaoxue, Lee, Seunghyun, Ishii, Akina, Yamagata, Kaoru, Nakano, Kazuhisa, Tanaka, Yoshiya

“…The purpose of this study was to elucidate the mechanism of action of baricitinib on Janus kinase (JAK)/signal transducer and activator of transcription (STAT)…”
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Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis by Iwata, Shigeru, Zhang, Mingzeng, Hajime, Maiko, Ohkubo, Naoaki, Sonomoto, Koshiro, Torimoto, Keiichi, Kitanaga, Yukihiro, Trimova, Gulzhan, Todoroki, Yasuyuki, Miyata, Hiroko, Ueno, Masanobu, Nagayasu, Atsushi, Kanda, Ryuichiro, Nakano, Kazuhisa, Nakayamada, Shingo, Sakata, Kei, Tanaka, Yoshiya

“…B cells play an important pathological role in RA. In this study, we investigated the role of metabolic regulator mTOR in B cells and its relevance to the…”
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Sequential regulation of gibberellin, brassinosteroid, and jasmonic acid biosynthesis occurs in rice [Oryza sativa] coleoptiles to control the transcript levels of anti-microbial Thionin genes by Kitanaga, Y.(Tokyo Univ. (Japan)), Jian, C, Hasegawa, M, Yazaki, J, Kishimoto, N, Kikuchi, S, Nakamura, H, Ichikawa, H, Asami, T, Yoshida, S, Yamaguchi, I, Suzuki, Y

“…Transcripts of thionin genes encoding antimicrobial peptides were present at a high level in rice coleoptiles just after germination, and decreased to an…”
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In vitro pharmacological effects of peficitinib on lymphocyte activation: a potential treatment for systemic sclerosis with JAK inhibitors by Kitanaga, Yukihiro, Imamura, Emiko, Nakahara, Yutaka, Fukahori, Hidehiko, Fujii, Yasutomo, Kubo, Satoshi, Nakayamada, Shingo, Tanaka, Yoshiya

“…Abstract Objectives Peficitinib, a novel Janus kinase (JAK) inhibitor, demonstrated promising results in treating RA in phase 3 clinical trials. This in vitro…”
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WITHDRAWN: Kdm5a promotes B cell activation in systemic lupus erythematosus via downregulation of A20 by histone modification by Fan, Jie, Iwata, S., Tanaka, Yoshiya, Kitanaga, Yukihiro, Ishii, Akina, Maiko, Hara, Zhang, Xueqiang, Liu, Xingde

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Discovery of a novel Igβ and FcγRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosus by Kitanaga, Yukihiro, Yamajuku, Daisuke, Kubo, Satoshi, Nakamura, Koji, Maeda, Masashi, Seki, Mutsumi, Kaneko, Yoko, Kinugasa, Fumitaka, Morokata, Tatsuaki, Kondo, Yuya, Yoshinari, Hiroko, Nakayamada, Shingo, Sumida, Takayuki, Tanaka, Yoshiya

“…•A novel anti-Igβ antibody with enhanced affinity for FcγRIIB was discovered.•ASP2713 dominantly bound to B cell and induced intrinsic negative feedback…”
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Kdm5a promotes B cell activation in systemic lupus erythematosus via downregulation of A20 by histone modification by Fan, Jie, Iwata, S, Tanaka, Yoshiya, Kitanaga, Yukihiro, Ishii, Akina, Maiko, Hara, Zhang, Xueqiang, Liu, Xingde

“…Systemic lupus erythematosus (SLE) is a classic autoimmune connective tissue disease, which leads to multiple organ system injury. Tumor necrosis…”
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Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus by Yoshikawa, Maiko, Nakayamada, Shingo, Kubo, Satoshi, Nawata, Aya, Kitanaga, Yukihiro, Iwata, Shigeru, Sakata, Kei, Ma, Xiaoxue, Wang, Sheau Pey, Nakano, Kazuhisa, Saito, Kazuyoshi, Tanaka, Yoshiya

“…Memory B cells are increased in systemic lupus erythematosus (SLE) cases, but the qualitative abnormalities and induction mechanism of these cells are unclear…”
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