Search Results - "Kitajima, I."

Physical and functional interaction of the active zone protein CAST/ERC2 and the  -subunit of the voltage-dependent Ca2+ channel by Kiyonaka, S., Nakajima, H., Takada, Y., Hida, Y., Yoshioka, T., Hagiwara, A., Kitajima, I., Mori, Y., Ohtsuka, T.

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Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in crow-fukase (POEMS) syndrome by Watanabe, Osamu, Maruyama, Ikuro, Arimura, Kimiyoshi, Kitajima, Isao, Arimura, Hitoshi, Hanatani, Mitsuya, Matsuo, Katsuhiko, Arisato, Takayo, Osame, Mitsuhiro

“…Crow–Fukase or POEMS syndrome of polyneuropathy, organomegaly, endocrinopathy, M‐protein, and skin changes is a rare multisystem disorder of obscure…”
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Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome by Watanabe, O, Arimura, K, Kitajima, I, Osame, M, Maruyama, I

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Vascular endothelial growth factor (VEGF) is one of the cytokines causative and predictive of hepatic veno-occlusive disease (VOD) in stem cell transplantation by IGUCHI, A, KOBAYASHI, R, YOSHIDA, M, KOBAYASHI, K, MATSUO, K, KITAJIMA, I, MARUYAMA, I

“…Hepatic veno-occlusive disease (VOD) is one of the most serious complications in patients receiving stem cell transplantation (SCT). However, the cause of VOD…”
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Pharmacokinetic study of darbepoetin alfa: Absorption, distribution, and excretion after a single intravenous and subcutaneous administration to rats by Yoshioka, E., Kato, K., Shindo, H., Mitsuoka, C., Kitajima, S.-I., Ogata, H., Misaizu, T.

“…KRN321 is a hyperglycosylated analogue of recombinant human erythropoietin (rHuEPO, epoetin alfa), and its absorption, distribution, and excretion have been…”
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Ceramide-induced nuclear translocation of NF-κB is a potential mediator of the apoptotic response to TNF-α in murine clonal osteoblasts by Kitajima, I., Soejima, Y., Takasaki, I., Beppu, H., Tokioka, T., Maruyama, I.

“…Osteoblasts are affected by TNF-α overproduction by immune cells during inflammation. We demonstrate that apoptosis is induced in murine osteoblastic MC3T3-E1…”
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Apoptotic cell death in steroid induced osteonecrosis: an experimental study in rabbits by Kabata, T, Kubo, T, Matsumoto, T, Nishino, M, Tomita, K, Katsuda, S, Horii, T, Uto, N, Kitajima, I

“…We investigated apoptosis, i.e., programmed cell death, in steroid induced osteonecrosis in a rabbit model. Forty-four adult Japanese White rabbits were…”
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The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells by Arisato, T., Sarker, K. P., Kawahara, K., Nakata, M., Hashiguchi, T., Osame, M., Kitajima, I., Maruyama, I.

“…Thrombin, a serine protease generated by the activation of the blood coagulation cascade following vessel injury, induces vascular endothelial growth factor…”
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Thrombin receptor mediated signals induce expressions of interleukin 6 and granulocyte colony stimulating factor via NF-κB activation in synovial fibroblasts by Shin, Hiroshi, Kitajima, Isao, Nakajima, Toshihiro, Shao, Qing, Tokioka, Takeshi, Takasaki, Ikuko, Hanyu, Naohiro, Kubo, Toshikazu, Maruyama, Ikuro

“…OBJECTIVE To clarify the mechanism of thrombin receptor mediated signal transduction and the induction of cytokines by thrombin stimulation in rheumatoid…”
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Hydrostatic pressure induces expression of interleukin 6 and tumour necrosis factor α mRNAs in a chondrocyte-like cell line by Takahashi, Kenji, Kubo, Toshikazu, Arai, Yuji, Kitajima, Isao, Takigawa, Masaharu, Imanishi, Jiro, Hirasawa, Yasusuke

“…OBJECTIVE To clarify the effect of pressure on the expressions of proteoglycan core protein and metabolism related cytokines in a chondrocyte-like cell line,…”
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Serum samples of patients with rheumatoid arthritis contain a specific autoantibody to “denatured” aldolase A in the osteoblast-like cell line, MG-63 by Ukaji, Fumio, Kitajima, Isao, Kubo, Toshikazu, Shimizu, Choji, Nakajima, Toshihiro, Maruyama, Ikuro

“…OBJECTIVE To identify rheumatoid arthritis (RA) specific autoantibody and its antigen in the human osteoblast-like cell line, MG-63. METHODS MG-63 cell extract…”
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Nitric oxide-mediated apoptosis in murine mastocytoma by Kitajima, I, Kawahara, K, Nakajima, T, Soejima, Y, Matsuyama, T, Maruyama, I

“…To investigate how the number of mast cells is controlled, we studied a murine mastocytoma cell line. Based on electron microscopic observation of nuclear…”
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Expression of transduced HSP70 gene protects chondrocytes from stress by KUBO, Toshikazu, ARAI, Yuji, TAKAHASHI, Kenji, IKEDA, Takumi, OHASHI, Suzuyo, KITAJIMA, Isao, MAZDA, Osam, TAKIGAWA, Masaharu, IMANISHI, Jiro, HIRASAWA, Yasusuke

“…OBJECTIVE: To investigate the efficacy of adenovirus vector mediated transduction of heat shock protein 70 (HSP70) gene to human chondrocyte-like cell…”
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Inhibition of caspase-3 activation by SB 203580, p38 mitogen-activated protein kinase inhibitor in nitric oxide-induced apoptosis of PC-12 cells by Sarker, K P, Nakata, M, Kitajima, I, Nakajima, T, Maruyama, I

“…Mitogen-activated protein kinase (MAPK) p38 plays pivotal role in cell proliferation, differentiation, and apoptosis when cysteine protease caspase induces…”
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Novel rapid identification and quantification method of bacteria in a septic blood sample can produce an effective biomarker for monitoring patient care by Niimi, H., Miyakoshi, A., Ueno, T., Wakasugi, M., Higashi, Y., Hayashi, A., Yamamoto, Y., Kitajima, I.

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Molecular pathomechanism of HTLV-I infectious diseases by Kitajima, I

“…Human T-cell lymphotropic virus type I(HTLV-I) is a type C retrovirus, closely associated with adult T-cell leukemia. In the past few years, studies have…”
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Involvement of NF-kappa B activation in thrombin-induced human vascular smooth muscle cell proliferation by Nakajima, T, Kitajima, I, Shin, H, Takasaki, I, Shigeta, K, Abeyama, K, Yamashita, Y, Tokioka, T, Soejima, Y, Maruyama, I

“…A thrombin receptor has been cloned and is thought to mediate a variety of thrombin-induced responses. However, the transcription factors important for…”
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Human T-cell leukemia virus type I tax transformation is associated with increased uptake of oligodeoxynucleotides in vitro and in vivo by KITAJIMA, I, SHINOHARA, T, MINOR, T, BIBBS, L, BILAKOVICS, J, NERENBERG, M

“…We have utilized antisense oligodeoxynucleotides (ODNs) to modulate transcriptional activation by the human T-cell leukemia virus type I (HTLV-I) tax gene, the…”
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Development and application of non-radio isotropic PCR-SSCP analysis for genetic diagnosis by Kitajima, I

“…We applied a new and powerful technique for genetic diagnosis, so called reverse transcript-polymerase chain reaction-single strand conformation polymorphism…”
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Spaceflight effects on beta-adrenoceptor and metabolic properties in rat plantaris by Ohira, Y, Yasui, W, Kariya, F, Tanaka, T, Kitajima, I, Maruyama, I, Nagaoka, S, Sekiguchi, C, Hinds, W E

“…Effects of 14 days of spaceflight on beta-adrenoceptor (beta-AR), mitochondrial enzyme activities, and fiber type composition were studied in plantaris muscles…”
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