Search Results - "Kitadai, Yuki"

Pexidartinib and Immune Checkpoint Inhibitors Combine to Activate Tumor Immunity in a Murine Colorectal Cancer Model by Depleting M2 Macrophages Differentiated by Cancer-Associated Fibroblasts by Shimizu, Daisuke, Yuge, Ryo, Kitadai, Yuki, Ariyoshi, Misa, Miyamoto, Ryo, Hiyama, Yuichi, Takigawa, Hidehiko, Urabe, Yuji, Oka, Shiro

“…Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) are known to play supportive roles in tumor development and progression, but their…”
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WEE1 Inhibitor Adavosertib Exerts Antitumor Effects on Colorectal Cancer, Especially in Cases with p53 Mutations by Ariyoshi, Misa, Yuge, Ryo, Kitadai, Yuki, Shimizu, Daisuke, Miyamoto, Ryo, Yamashita, Ken, Hiyama, Yuichi, Takigawa, Hidehiko, Urabe, Yuji, Oka, Shiro

“…Inhibition of WEE1, a key regulator of the G2/M checkpoint of the cell cycle, induces apoptosis by initiating mitosis without repairing DNA damage. However,…”
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Abstract 5087: Precise characterization of macrophage secretory exosomes can lead to novel therapeutic approaches by Bednarczyk, Robert Bronislaw, Kitadai, Yuki, Tuli, Neha Y., Hanly, Elyse K., Benrahoma, Ghada, Mittelman, Abraham, Tiwari, Raj K.

“…Abstract Multiple cell types interact within the tumor microenvironment (TME) through crosstalk events that are mediated by many biomolecules including…”
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