Search Results - "Kita, Yoshiaki"
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Combined neutrophil-lymphocyte ratio and platelet-lymphocyte ratio predicts chemotherapy response and prognosis in patients with advanced gastric cancer
Published in BMC cancer (08-07-2019)“…The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are representative blood markers of systemic inflammatory responses. However, the…”
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RNA sequencing-based microRNA expression signature in esophageal squamous cell carcinoma: oncogenic targets by antitumor miR-143-5p and miR-143-3p regulation
Published in Journal of human genetics (01-11-2020)“…Aberrantly expressed microRNAs (miRNAs) disrupt intracellular RNA networks and contribute to malignant transformation of cancer cells. Utilizing the latest RNA…”
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3
Combined fibrinogen and neutrophil‐lymphocyte ratio as a prognostic marker of advanced esophageal squamous cell carcinoma
Published in Cancer science (01-02-2017)“…Patients with advanced esophageal squamous cell carcinoma (ESCC) is received chemoradiotherapy or chemotherapy for clinical management. However, it is…”
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Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS8
Published in Journal of human genetics (01-06-2019)“…Our ongoing analyses identifying dysregulated microRNAs (miRNAs) and their controlled target RNAs have shed light on novel oncogenic pathways in pancreatic…”
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Dual midbrain and forebrain origins of thalamic inhibitory interneurons
Published in eLife (01-02-2021)“…The ubiquitous presence of inhibitory interneurons in the thalamus of primates contrasts with the sparsity of interneurons reported in mice. Here, we identify…”
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Molecular pathogenesis of pancreatic ductal adenocarcinoma: Impact of passenger strand of pre‐miR‐148a on gene regulation
Published in Cancer science (01-06-2018)“…We previously used RNA sequencing to establish the microRNA (miRNA) expression signature of pancreatic ductal adenocarcinoma (PDAC). We found that both strands…”
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Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma
Published in Nature communications (24-11-2017)“…Notch1 transactivates Notch3 to drive terminal differentiation in stratified squamous epithelia. Notch1 and other Notch receptor paralogs cooperate to act as a…”
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ZFP36L2 promotes cancer cell aggressiveness and is regulated by antitumor microRNA‐375 in pancreatic ductal adenocarcinoma
Published in Cancer science (01-01-2017)“…Due to its aggressive nature, pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal and hard‐to‐treat malignancies. Recently developed targeted…”
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Anatomical study of the inferior mesenteric vein using three-dimensional computed tomography angiography in laparoscopy-assisted surgery for left-sided colorectal cancer
Published in Surgery today (Tokyo, Japan) (01-10-2021)“…Purpose To investigate the drainage patterns of the inferior mesenteric vein (IMV) and measure the distance from the root of the inferior mesenteric artery…”
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10
Noncoding RNA and colorectal cancer: its epigenetic role
Published in Journal of human genetics (01-01-2017)“…The use of novel sequencing and high-throughput techniques has become widespread, and are now readily available to obtain the comprehensive transcription…”
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PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers
Published in Cancer discovery (01-03-2015)“…Protein arginine methyltransferase 5 (PRMT5) has been implicated as a key modulator of lymphomagenesis. Whether PRMT5 has overt oncogenic function in the…”
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Cellular-resolution gene expression profiling in the neonatal marmoset brain reveals dynamic species- and region-specific differences
Published in Proceedings of the National Academy of Sciences - PNAS (04-05-2021)“…Precise spatiotemporal control of gene expression in the developing brain is critical for neural circuit formation, and comprehensive expression mapping in the…”
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13
Vascular endothelial growth factor inhibitors promote antitumor responses via tumor microenvironment immunosuppression in advanced colorectal cancer
Published in Scandinavian journal of gastroenterology (02-09-2023)“…This study aims to investigate changes in the tumor immune environment of patients who underwent therapy with a vascular endothelial growth factor (VEGF)…”
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Regulation of MMP13 by antitumor microRNA-375 markedly inhibits cancer cell migration and invasion in esophageal squamous cell carcinoma
Published in International journal of oncology (01-12-2016)“…Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies. Recently developed molecular targeted therapies are not available for…”
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Multidisciplinary treatment of advanced or recurrent solid pseudopapillary neoplasm of the pancreas: three case reports
Published in Surgical case reports (10-01-2022)“…Background Solid pseudopapillary neoplasm (SPN) is a rare pancreatic tumor that predominantly affects young females. Prognosis is excellent; however, 10–15% of…”
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Regulation of SPOCK1 by dual strands of pre-miR-150 inhibit cancer cell migration and invasion in esophageal squamous cell carcinoma
Published in Journal of human genetics (01-11-2017)“…Analysis of our microRNA (miRNA) expression signatures of human cancers based on RNA sequencing have shown that both strands of pre-miR-150, miR-150-5p (the…”
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Molecular Pathogenesis of Colorectal Cancer: Impact of Oncogenic Targets Regulated by Tumor Suppressive miR-139-3p
Published in International journal of molecular sciences (01-10-2022)“…We recently determined the RNA sequencing-based microRNA (miRNA) expression signature of colorectal cancer (CRC). Analysis of the signature showed that the…”
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In vivo imaging of cortical interneurons migrating in the intermediate/subventricular zones
Published in Neuroscience research (01-09-2016)“…•We visualized migrating neurons at a depth of the cortex in vivo.•Stable and long-term observation of migrating cortical interneurons was…”
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Programmed death‐ligand 1 is a promising blood marker for predicting tumor progression and prognosis in patients with gastric cancer
Published in Cancer science (01-03-2018)“…Immune checkpoint inhibitor therapy has been clinically introduced for several malignancies, and its effectiveness has been confirmed by clinical trials. In…”
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From migration to settlement: the pathways, migration modes and dynamics of neurons in the developing brain
Published in Proceedings of the Japan Academy, Series B (01-01-2016)“…Neuronal migration is crucial for the construction of the nervous system. To reach their correct destination, migrating neurons choose pathways using physical…”
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