Search Results - "Kita, Hiroko"

A Paradigm Shift: The Reclassification of SARS-CoV-2 and Longitudinal Immune Responses in Japanese Healthcare Workers by Chano, Tokuhiro, Kita, Hiroko, Yamashita, Tomoko, Fujimura, Hirokazu, Ikemoto, Toshiyuki

“…Under the aegis of the National Infectious Diseases Act, the virus transitioned from a category 2 menace to category 5, analogous to seasonal influenza. For…”
Get full text

Prominent role of RAB39A-RXRB axis in cancer development and stemness by Chano, Tokuhiro, Kita, Hiroko, Avnet, Sofia, Lemma, Silvia, Baldini, Nicola

“…In this study, we found that , a member of the RAS oncogene family, was selectively expressed in cancer cells of different histotypes, by analyzing gene…”
Get full text

Effectiveness of COVID-19 vaccination in healthcare workers in Shiga Prefecture, Japan by Chano, Tokuhiro, Yamashita, Tomoko, Fujimura, Hirokazu, Kita, Hiroko, Ikemoto, Toshiyuki, Kume, Shinji, Morita, Shin-ya, Suzuki, Tomoyuki, Kakuno, Fumihiko

“…This study, which included serological and cellular immunity tests, evaluated whether coronavirus disease 2019 (COVID-19) vaccination adequately protected…”
Get full text

Cardiac myocyte force development during differentiation and maturation by Jacot, Jeffrey G., Kita-Matsuo, Hiroko, Wei, Karen A., Vincent Chen, H.S., Omens, Jeffrey H., Mercola, Mark, McCulloch, Andrew D.

“…The maturation of cardiac myocytes during the immediate prenatal period coincides with changes in the mechanical properties of the extracellular matrix. We…”
Get full text

Dimethyl sulfoxide induces chemotherapeutic resistance in the treatment of testicular embryonal carcinomas by KITA, HIROKO, OKAMOTO, KEISEI, KUSHIMA, RYOJI, KAWAUCHI, AKIHIRO, CHANO, TOKUHIRO

“…Dimethyl sulfoxide (DMSO) is an amphipathic molecule that is used as a solvent in biological studies and as a vehicle for drug therapy. The present study was…”
Get full text

Therapeutic potential of SOX2 inhibition for embryonal carcinoma by Ushida, Hiroshi, Chano, Tokuhiro, Minami, Kahori, Kita, Hiroko, Kawakami, Takahiro, Okabe, Hidetoshi, Okada, Yusaku, Okamoto, Keisei

“…Some nonseminomatous germ cell tumors are resistant to any type of chemotherapy. Control of embryonal carcinoma cells is crucial to manage nonseminomatous germ…”
Get more information

Autonomic nervous system activity and the state and development of obesity in Japanese school children by Nagai, N, Matsumoto, T, Kita, H, Moritani, T

“…Objective: The autonomic nervous system (ANS) plays an important role in regulating energy expenditure and body fat content; however, the extent to which the…”
Get full text

Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes by Kita-Matsuo, Hiroko, Barcova, Maria, Prigozhina, Natalie, Salomonis, Nathan, Wei, Karen, Jacot, Jeffrey G, Nelson, Brandon, Spiering, Sean, Haverslag, René, Kim, Changsung, Talantova, Maria, Bajpai, Ruchi, Calzolari, Diego, Terskikh, Alexey, McCulloch, Andrew D, Price, Jeffrey H, Conklin, Bruce R, Chen, H S Vincent, Mercola, Mark

“…Developmental, physiological and tissue engineering studies critical to the development of successful myocardial regeneration therapies require new ways to…”
Get full text

Molecular features of non-B, non-C hepatocellular carcinoma: a PCR-array gene expression profiling study by Kurokawa, Yukinori, Matoba, Ryo, Takemasa, Ichiro, Nakamori, Shoji, Tsujie, Masanori, Nagano, Hiroaki, Dono, Keizo, Umeshita, Koji, Sakon, Masato, Ueno, Noriko, Kita, Hiroko, Oba, Shigeyuki, Ishii, Shin, Kato, Kikuya, Monden, Morito

“…Background/Aims: Hepatocellular carcinoma (HCC) usually develops following chronic liver inflammation caused by hepatitis C or B virus. Through expression…”
Get full text

Expression profiling by iAFLP: A PCR-based method for genome-wide gene expression profiling by Kawamoto, S, Ohnishi, T, Kita, H, Chisaka, O, Okubo, K

“…The availability of comprehensive sets of genes has prompted the researchers to carry out systematic collection of gene expression data. RT-PCR has the highest…”
Get full text

Gene expression during the development of experimentally induced cerebral aneurysms by Sadamasa, Nobutake, Nozaki, Kazuhiko, Kita-Matsuo, Hiroko, Saito, Sakae, Moriwaki, Takuya, Aoki, Tomohiro, Kawarazaki, Satoshi, Kataoka, Hiroharu, Takagi, Yasushi, Ishikawa, Masatsune, Hashimoto, Nobuo, Kato, Kikuya

“…Cerebral aneurysms are a major cause of subarachnoid hemorrhage, but the mechanism of their development remains unclear. In this study, we investigated…”
Get more information

Pro-GA, a Novel Inhibitor of γ-Glutamylcyclotransferase, Suppresses Human Bladder Cancer Cell Growth by Hanada, Eiki, Kageyama, Susumu, Murai, Ryosuke, Kubota, Shigehisa, Ii, Hiromi, Nakata, Susumu, Kita, Hiroko, Kawauchi, Akihiro, Chano, Tokuhiro

“…γ-Glutamylcyclotransferase (GGCT), a key enzyme involved in glutathione metabolism, catalyzes a specific reaction that generates 5-oxoproline and free amino…”
Get full text

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease by WYTTENBACH, Andreas, SWARTZ, Jina, KATO, Kikuya, RUBINSZTEIN, David C, KITA, Hiroko, THYKJAER, Thomas, CARMICHAEL, Jenny, BRADLEY, Jane, BROWN, Rosemary, MAXWELL, Michelle, SCHAPIRA, Anthony, ORNTOFT, Torben F

“…Huntington's disease (HD) is one of 10 known diseases caused by a (CAG)(n) trinucleotide repeat expansion that is translated into an abnormally long…”
Get full text

Raised intracellular glucose concentrations reduce aggregation and cell death caused by mutant huntingtin exon 1 by decreasing mTOR phosphorylation and inducing autophagy by Ravikumar, Brinda, Stewart, Abigail, Kita, Hiroko, Kato, Kikuya, Duden, Rainer, Rubinsztein, David C.

“…Huntington's disease is caused by a CAG trinucleotide repeat expansion that is translated into an abnormally long polyglutamine tract. This gain-of-function…”
Get full text

RB1CC1 Protein Suppresses Type II Collagen Synthesis in Chondrocytes and Causes Dwarfism by Nishimura, Ichiro, Chano, Tokuhiro, Kita, Hiroko, Matsusue, Yoshitaka, Okabe, Hidetoshi

“…RB1-inducible coiled-coil 1 (RB1CC1) functions in various processes, such as cell growth, differentiation, senescence, apoptosis, and autophagy. The…”
Get full text

Modulation of polyglutamine-induced cell death by genes identified by expression profiling by Kita, Hiroko, Carmichael, Jenny, Swartz, Jina, Muro, Shizuko, Wyttenbach, Andreas, Matsubara, Kenichi, Rubinsztein, David C., Kato, Kikuya

“…The majority of triplet-repeat diseases are caused by mutated genes with an extended polyglutamine tract, exemplified by Huntington's disease (HD). In order to…”
Get full text

An expression profile of active genes in cultured human keratinocytes by Kita, H, Okubo, K, Matsubara, K

“…An expression profile of genes active in cultured human keratinocytes was obtained by collecting 770 partial sequences from a 3'-directed cDNA library that…”
Get full text

Gene expression profiling of cerebellar development with high-throughput functional analysis by Saito, Sakae, Honma, Kimi, Kita-Matsuo, Hiroko, Ochiya, Takahiro, Kato, Kikuya

“…1 Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, and Core Research for Evolutional Science and Technology, Japan Science…”
Get full text

Central genetic alterations common to all HCV-positive, HBV-positive and non-B, non-C hepatocellular carcinoma : A new approach to identify novel tumor markers by KUROKAWA, Yukinori, HONMA, Kimi, KATO, Kikuya, TAKEMASA, Ichiro, NAKAMORI, Shoji, KITA-MATSUO, Hiroko, MOTOORI, Masaaki, NAGANO, Hiroaki, DONO, Keizo, OCHIYA, Takahiro, MONDEN, Morito

“…Hepatocellular carcinoma (HCC) is a common malignancy, but the prognosis remains poor due to the lack of sensitive diagnostic markers. To gain insight into the…”
Get full text

Adaptor-tagged competitive polymerase chain reaction: amplification bias and quantified gene expression levels by Kita-Matsuo, Hiroko, Yukinawa, Naoto, Matoba, Ryo, Saito, Sakae, Oba, Shigeyuki, Ishii, Shin, Kato, Kikuya

“…Adaptor-tagged competitive polymerase chain reaction (ATAC-PCR) is an advanced version of quantitative competitive PCR characterized by the addition of unique…”
Get full text