Search Results - "Kisucká, Alexandra"
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Activation of Neuroprotective Microglia and Astrocytes at the Lesion Site and in the Adjacent Segments Is Crucial for Spontaneous Locomotor Recovery after Spinal Cord Injury
Published in Cells (Basel, Switzerland) (30-07-2021)“…Microglia and astrocytes play an important role in the regulation of immune responses under various pathological conditions. To detect environmental cues…”
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Glial-Neuronal Interactions in Pathogenesis and Treatment of Spinal Cord Injury
Published in International journal of molecular sciences (17-12-2021)“…Traumatic spinal cord injury (SCI) elicits an acute inflammatory response which comprises numerous cell populations. It is driven by the immediate response of…”
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Activation of Three Major Signaling Pathways After Endurance Training and Spinal Cord Injury
Published in Molecular neurobiology (01-02-2022)“…We aimed to investigate the effects of endurance training on expression of growth factors (GFs) and stimulation of neurotrophin-dependent signaling pathways…”
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Impact of Endurance Training on Regeneration of Axons, Glial Cells, and Inhibitory Neurons after Spinal Cord Injury: A Link between Functional Outcome and Regeneration Potential within the Lesion Site and in Adjacent Spinal Cord Tissue
Published in International journal of molecular sciences (11-05-2023)“…Endurance training prior to spinal cord injury (SCI) has a beneficial effect on the activation of signaling pathways responsible for survival, neuroplasticity,…”
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Epidural oscillating field stimulation increases axonal regenerative capacity and myelination after spinal cord trauma
Published in Neural regeneration research (01-12-2022)“…Oscillating field stimulation (OFS) with regular alterations in the polarity of electric current is a unique, experimental approach to stimulate, support, and…”
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A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome
Published in International journal of molecular sciences (07-04-2018)“…The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol…”
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Is Innervation of the Neuromuscular Junction at the Diaphragm Modulated by sGC/cGMP Signaling?
Published in Frontiers in physiology (23-06-2020)“…We previously reported NO/sGC signaling in the upper respiratory pathway, receiving input from the respiratory neurons of the brainstem to phrenic motoneurons…”
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THE EFFECT OF SUBPIAL DELIVERY OF CHONDROITINASE ABC ON REGULATING PI3K/AKT SIGNALING PATHWAY AFTER SCI
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Combined therapy (Rho-A-kinase inhibitor and chitosan/collagen porous scaffold) provides a supportive environment for endogenous regenerative processes after spinal cord trauma
Published in Archives italiennes de biologie (25-01-2022)“…Due to the complexity of pathological processes in spinal cord injury (SCI), it is increasingly recognized that combined strategies are more effective than…”
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Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal cord injury in rat spinal cord
Published in The spine journal (01-06-2015)“…Abstract Background context The loss of descending control after spinal cord injury (SCI) and incessant stimulation of Ia monosynaptic pathway, carrying…”
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Spinal cord transection modifies neuronal nitric oxide synthase expression in medullar reticular nuclei and in the spinal cord and increases parvalbumin immunopositivity in motoneurons below the site of injury in experimental rabbits
Published in Acta histochemica (01-09-2012)“…Using immunohistochemistry, we detected the expression of neuronal nitric oxide synthase (nNOS) in ventral medullary gigantocellular reticular nuclei and in…”
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The vulnerability of nitrergic neurons to transient spinal cord ischemia: a quantitative immunohistochemical and histochemical study
Published in Journal of molecular histology (01-04-2012)“…Spinal cord ischemia belongs to serious and relatively frequent diseases of CNS. The aim of the present study was to find out the vulnerability of nitrergic…”
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Hypothermic treatment after computer-controlled compression in minipig: A preliminary report on the effect of epidural vs. direct spinal cord cooling
Published in Experimental and therapeutic medicine (01-12-2018)“…The aim of the present study was to investigate the therapeutic efficacy of local hypothermia (beginning 30 min post-injury persisting for 5 h) on tissue…”
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Molecular mechanisms underlying functional recovery after spinal cord injury
Published in IBRO reports (01-09-2019)Get full text
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