Search Results - "Kistemaker, Hans A.V"

Chemoselective Cleavage of p‑Methoxybenzyl and 2‑Naphthylmethyl Ethers Using a Catalytic Amount of HCl in Hexafluoro-2-propanol by Volbeda, Anne Geert, Kistemaker, Hans A.V, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V, Codée, Jeroen D.C

“…A new, fast, mild and chemoselective deprotection method to cleave p-methoxybenzyl and 2-naphthylmethyl ethers using catalytic amounts of hydrochloric acid in…”
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Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides by Kistemaker, Hans A. V., Nardozza, Aurelio Pio, Overkleeft, Herman S., van der Marel, Gijs A., Ladurner, Andreas G., Filippov, Dmitri V.

“…Mono‐ADP‐ribosylation is a dynamic posttranslational modification (PTM) with important roles in signaling. Mammalian proteins that recognize or hydrolyze…”
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Synthesis, Reactivity, and Stereoselectivity of 4‑Thiofuranosides by Madern, Jerre M, Hansen, Thomas, van Rijssel, Erwin R, Kistemaker, Hans A.V, van der Vorm, Stefan, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V, Codée, Jeroen D.C

“…Thiosugars, sugars that have their endocyclic oxygen substituted for a sulfur atom, have been used as stable bioisosteres of naturally occurring glycans…”
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A General Approach Towards Triazole‐Linked Adenosine Diphosphate Ribosylated Peptides and Proteins by Liu, Qiang, Kistemaker, Hans A. V., Bhogaraju, Sagar, Dikic, Ivan, Overkleeft, Herman S., van der Marel, Gijsbert A., Ovaa, Huib, van der Heden van Noort, Gerbrand J., Filippov, Dmitri V.

“…Current methods to prepare adenosine diphosphate ribosylated (ADPr) peptides are not generally applicable due to the labile nature of this post‐translational…”
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Synthesis of Well-Defined Adenosine Diphosphate Ribose Oligomers by Kistemaker, Hans A. V., Lameijer, Lucien N., Meeuwenoord, Nico J., Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V.

“…The post‐translational modification of proteins that is known as adenosine diphosphate ribosylation (ADPr) regulates a wide variety of important biological…”
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ADPr-Peptide Synthesis by Kistemaker, Hans A V, Voorneveld, Jim, Filippov, Dmitri V

“…Synthetic mono-ADPr-peptides are useful for structural, biochemical, and proteomics studies. We describe here a protocol for the preparation of…”
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Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches by Szymański, Wiktor, Beierle, John M, Kistemaker, Hans A. V, Velema, Willem A, Feringa, Ben L

“…Issues surrounding the reversible photocontrol of biological systems by the incorporation of molecular photoswitches are examined. Photoswitches are used for…”
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ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence by McPherson, Robert Lyle, Abraham, Rachy, Sreekumar, Easwaran, Ong, Shao-En, Cheng, Shang-Jung, Baxter, Victoria K., Kistemaker, Hans A. V., Filippov, Dmitri V., Griffin, Diane E., Leung, Anthony K. L.

“…Chikungunya virus (CHIKV), an Old World alphavirus, is transmitted to humans by infected mosquitoes and causes acute rash and arthritis, occasionally…”
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4‑Thioribose Analogues of Adenosine Diphosphate Ribose (ADPr) Peptides by Madern, Jerre M., Voorneveld, Jim, Rack, Johannes G. M., Kistemaker, Hans A. V., Ahel, Ivan, van der Marel, Gijsbert A., Codée, Jeroen D. C., Filippov, Dmitri V.

“…Adenosine diphosphate (ADP) ribosylation is an important post-translational modification (PTM) that plays a role in a wide variety of cellular processes. To…”
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New Quantitative Mass Spectrometry Approaches Reveal Different ADP-ribosylation Phases Dependent On the Levels of Oxidative Stress by Bilan, Vera, Selevsek, Nathalie, Kistemaker, Hans A.V., Abplanalp, Jeannette, Feurer, Roxane, Filippov, Dmitri V., Hottiger, Michael O.

“…Oxidative stress is a potent inducer of protein ADP-ribosylation. Although individual oxidative stress-induced ADP-ribosylated proteins have been identified,…”
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Synthesis of ribosyl-ribosyl-adenosine-5',5'',5'''(triphosphate)-the naturally occurring branched fragment of poly(ADP ribose) by Liu, Qiang, Kistemaker, Hans A V, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V

“…Poly-adenosine diphosphate ribose (PAR) is a branched biopolymer that occurs as a result of post-translational modification of proteins. In 1981 Miwa et al…”
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Branching of poly(ADP-ribose): Synthesis of the Core Motif by Kistemaker, Hans A. V, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V

“…The synthesis of the core motif of branched poly­(adenosine diphosphate ribose) (poly­(ADPr)) is described, and structural analysis reasserted the proposed…”
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A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene by Singh, Hari R., Nardozza, Aurelio P., Möller, Ingvar R., Knobloch, Gunnar, Kistemaker, Hans A.V., Hassler, Markus, Harrer, Nadine, Blessing, Charlotte, Eustermann, Sebastian, Kotthoff, Christiane, Huet, Sébastien, Mueller-Planitz, Felix, Filippov, Dmitri V., Timinszky, Gyula, Rand, Kasper D., Ladurner, Andreas G.

“…DNA damage triggers chromatin remodeling by mechanisms that are poorly understood. The oncogene and chromatin remodeler ALC1/CHD1L massively decompacts…”
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Stereoselective Ribosylation of Amino Acids by Kistemaker, Hans A. V, van der Heden van Noort, Gerbrand J, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V

“…The glycosylation properties of ribofuranosyl N-phenyltrifluoroacetimidates toward carboxamide side chains of asparagine and glutamine were investigated…”
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On the Synthesis of Oligonucleotides Interconnected through Pyrophosphate Linkages by Kistemaker, Hans A. V., Meeuwenoord, Nico J., Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V.

“…In this article we revisit the synthetic methodology for oligonucleotides interconnected via pyrophosphates that relies on reactivity of phosphorodiamidous…”
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