Search Results - "Kissman, Elijah N."
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Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
Published in ACS central science (23-09-2020)“…The synthesis of protein–protein and protein–peptide conjugates is an important capability for producing vaccines, immunotherapeutics, and targeted delivery…”
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Expanding chemistry through in vitro and in vivo biocatalysis
Published in Nature (London) (04-07-2024)“…Living systems contain a vast network of metabolic reactions, providing a wealth of enzymes and cells as potential biocatalysts for chemical processes. The…”
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Reaction pathway engineering converts a radical hydroxylase into a halogenase
Published in Nature chemical biology (01-02-2022)“…Fe II /α-ketoglutarate (Fe II /αKG)-dependent enzymes offer a promising biocatalytic platform for halogenation chemistry owing to their ability to…”
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The Sinorhizobium meliloti nitrogen-fixing symbiosis requires CbrA-dependent regulation of a DivL and CckA phosphorelay
Published in Journal of bacteriology (24-10-2024)“…The cell cycle is a fundamental process involved in bacterial reproduction and cellular differentiation. For , cell cycle outcomes depend on its growth…”
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Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases
Published in Proceedings of the National Academy of Sciences - PNAS (21-03-2023)“…Biocatalytic C-H activation has the potential to merge enzymatic and synthetic strategies for bond formation. Fe /αKG-dependent halogenases are particularly…”
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