Search Results - "Kiso, Tetsuo"

Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodents by Murai, Nobuhito, Hiyama, Hideki, Kiso, Tetsuo, Sekizawa, Toshihiro, Watabiki, Tomonari, Oka, Hiromasa, Aoki, Toshiaki

“…Lysophosphatidic acid (LPA) is a bioactive lipid that acts via at least six G protein-coupled receptors, LPA receptors 1–6 (LPA1-6), for various physiological…”
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Effects of pregabalin and duloxetine on neurotransmitters in the dorsal horn of the spinal cord in a rat model of fibromyalgia by Kiso, Tetsuo, Moriyama, Ai, Furutani, Masako, Matsuda, Ritsuko, Funatsu, Yukiko

“…Dysfunction of the monoamine systems in the nervous system is associated with the clinical symptoms of fibromyalgia. Reserpine-induced myalgia (RIM) rats are a…”
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Intrathecal Administration of AS1928370, a Transient Receptor Potential Vanilloid 1 Antagonist, Attenuates Mechanical Allodynia in a Mouse Model of Neuropathic Pain by Watabiki, Tomonari, Kiso, Tetsuo, Tsukamoto, Mina, Aoki, Toshiaki, Matsuoka, Nobuya

“…Transient receptor potential vanilloid 1 (TRPV1) is primarily expressed in central and peripheral terminals of non-myelinated primary afferent neurons. We…”
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Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect by Watabiki, Tomonari, Kiso, Tetsuo, Kuramochi, Takahiro, Yonezawa, Koichi, Tsuji, Noriko, Kohara, Atsuyuki, Kakimoto, Shuichiro, Aoki, Toshiaki, Matsuoka, Nobuya

“…Transient receptor potential vanilloid 1 (TRPV1) is activated by a variety of stimulations, such as endogenous ligands and low pH, and is believed to play a…”
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Spinal mechanism of standard analgesics: Evaluation using mouse models of allodynia by Tsukamoto, Mina, Kiso, Tetsuo, Shimoshige, Yukinori, Aoki, Toshiaki, Matsuoka, Nobuya

“…Spinal neurotransmission plays an important role in the perception of pain signaling. In the present study, we investigated the spinal anti-nociceptive…”
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Allodynia and hyperalgesia in adjuvant-induced arthritic rats: time course of progression and efficacy of analgesics by Nagakura, Yukinori, Okada, Masamichi, Kohara, Atsuyuki, Kiso, Tetsuo, Toya, Takashi, Iwai, Akihiko, Wanibuchi, Fumikazu, Yamaguchi, Tokio

“…The complete Freund's adjuvant (CFA)-induced arthritic rat model has extensively served as a laboratory model in the study of arthritic pain. However, the time…”
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Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models by Kohara, Atsuyuki, Nagakura, Yukinori, Kiso, Tetsuo, Toya, Takashi, Watabiki, Tomonari, Tamura, Seiji, Shitaka, Yoshitsugu, Itahana, Hirotsune, Okada, Masamichi

“…Metabotropic glutamate receptor 1 (mGlu 1 receptor) has been suggested to play an important role in pain transmission. In this study, the effects of a…”
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Screening for Microtubule-Disrupting Antifungal Agents by Using a Mitotic-Arrest Mutant of Aspergillus nidulans and Novel Action of Phenylalanine Derivatives Accompanying Tubulin Loss by KISO, Tetsuo, FUJITA, Ken-Ichi, XU PING, TANAKA, Toshio, TANIGUCHI, Makoto

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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ASP8477, a fatty acid amide hydrolase inhibitor, exerts analgesic effects in rat models of neuropathic and dysfunctional pain by Kiso, Tetsuo, Watabiki, Tomonari, Sekizawa, Toshihiro

“…Exogenous cannabinoid receptor agonists are clinically effective for treating chronic pain but frequently cause side effects in the central nervous system…”
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Analgesic effects of ASP3662, a novel 11β‐hydroxysteroid dehydrogenase 1 inhibitor, in rat models of neuropathic and dysfunctional pain by Kiso, Tetsuo, Sekizawa, Toshihiro, Uchino, Hiroshi, Tsukamoto, Mina, Kakimoto, Shuichiro

“…Background and Purpose Glucocorticoids are a major class of stress hormones known to participate in stress‐induced hyperalgesia. Although 11β‐hydroxysteroid…”
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Analgesic effects of ASP 3662, a novel 11β‐hydroxysteroid dehydrogenase 1 inhibitor, in rat models of neuropathic and dysfunctional pain by Kiso, Tetsuo, Sekizawa, Toshihiro, Uchino, Hiroshi, Tsukamoto, Mina, Kakimoto, Shuichiro

“…Background and Purpose Glucocorticoids are a major class of stress hormones known to participate in stress‐induced hyperalgesia. Although 11β‐hydroxysteroid…”
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The effect of the selective 5-HT3 receptor agonist on ferret gut motility by Nagakura, Yukinori, Kiso, Tetsuo, Miyata, Keiji, Ito, Hiroyuki, Iwaoka, Kiyoshi, Yamaguchi, Tokio

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UK-2A, B, C and D, novel antifungal antibiotics from streptomyces sp. 517-02 VI (3). Role of substituents on dilactone ring of UK-2A and antimycin A3 against generation of reactive oxygen species in porcine renal proximal tubule LLC-PK1 cells by Fujita, Ken-Ichi, Kiso, Tetsuo, Usuki, Yoshinosuke, Tanaka, Toshio, Taniguchi, Makoto

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In vitro and in vivo pharmacological characterization of ASP8477: A novel highly selective fatty acid amide hydrolase inhibitor by Watabiki, Tomonari, Tsuji, Noriko, Kiso, Tetsuo, Ozawa, Tohru, Narazaki, Fumie, Kakimoto, Shuichiro

“…Although exogenous agonists for cannabinoid (CB) receptors are clinically effective for treating chronic pain, global activation of brain CB receptors causes…”
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A [K.sub.Ca]3.l Channel Opener, ASP08I9, Modulates Nociceptive Signal Processing from Peripheral Nerves in Fibromyalgia-Like Pain in Rats by Takeshita, Nobuaki, Oe, Tomoya, Kiso, Tetsuo, Kakimoto, Shuichiro

“…Purpose: Although abnormal peripheral and central pain processing has been observed in fibromyalgia (FM) patients, the biomechanics and pathophysiology,…”
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A K Ca 3.1 Channel Opener, ASP0819, Modulates Nociceptive Signal Processing from Peripheral Nerves in Fibromyalgia-Like Pain in Rats by Takeshita, Nobuaki, Oe, Tomoya, Kiso, Tetsuo, Kakimoto, Shuichiro

“…Although abnormal peripheral and central pain processing has been observed in fibromyalgia (FM) patients, the biomechanics and pathophysiology, surrounding the…”
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New thiazole derivatives as potent and selective 5-hydroxytriptamine 3 (5-HT3) receptor agonists for the treatment of constipation by IMANISHI, Naoki, IWAOKA, Kiyoshi, TSUKAMOTO, Shin-Ichi, MASE, Toshiyasu, KOSHIO, Hiroyuki, NAGASHIMA, Shin-Ya, KAZUTA, Ken-Ichi, OHTA, Mitsuaki, SAKAMOTO, Shuichi, ITO, Hiroyuki, AKUZAWA, Shinobu, KISO, Tetsuo

“…The syntheses and biological evaluation of a series of novel indeno[1,2-d]thiazole derivatives are described. Several groups reported 5-HT(3) receptor agonists…”
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L-2,5-dihydrophenylalanine, an inducer of cathepsin-dependent apoptosis in human promyelocytic leukemia cells (HL-60) by Kiso, T, Usuki, Y, Ping, X, Fujita, K, Taniguchi, M

“…L-2,5-Dihydrophenylalanine (DHPA), a phenylalanine analogue, induced apoptosis in human promyelocytic leukemia cells (HL-60). This apoptosis was demonstrated…”
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A KCa3.1 Channel Opener, ASP0819, Modulates Nociceptive Signal Processing from Peripheral Nerves in Fibromyalgia-Like Pain in Rats by Takeshita, Nobuaki, Oe, Tomoya, Kiso, Tetsuo, Kakimoto, Shuichiro

“…Purpose: Although abnormal peripheral and central pain processing has been observed in fibromyalgia (FM) patients, the biomechanics and pathophysiology,…”
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Design, synthesis, and biological evaluation of novel biphenyl-4-carboxamide derivatives as orally available TRPV1 antagonists by Oka, Hiromasa, Yonezawa, Koichi, Kamikawa, Akio, Ikegai, Kazuhiro, Asai, Norio, Shirakami, Shohei, Miyamoto, Satoshi, Watanabe, Toshihiro, Kiso, Tetsuo, Takemoto, Yukihiro, Tamura, Seiji, Kuramochi, Takahiro

“…[Display omitted] A new series of transient receptor potential vanilloid type 1 (TRPV1) antagonists were designed and synthesized from…”
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