Search Results - "Kislinger, Georg"
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Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex
Published in eLife (05-08-2024)“…Like other volume electron microscopy approaches, automated tape-collecting ultramicrotomy (ATUM) enables imaging of serial sections deposited on thick plastic…”
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2
Nonvesicular lipid transfer drives myelin growth in the central nervous system
Published in Nature communications (11-11-2024)“…Oligodendrocytes extend numerous cellular processes that wrap multiple times around axons to generate lipid-rich myelin sheaths. Myelin biogenesis requires an…”
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Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution
Published in iScience (24-07-2020)“…Volume electron microscopy enables the ultrastructural analysis of biological tissue. Currently, the techniques involving ultramicrotomy (ATUM, ssTEM) allow…”
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4
ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex
Published in STAR protocols (18-12-2020)“…Here, we describe a detailed workflow for ATUM-FIB microscopy, a hybrid method that combines serial-sectioning scanning electron microscopy (SEM) with focused…”
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5
Myelination generates aberrant ultrastructure that is resolved by microglia
Published in The Journal of cell biology (06-03-2023)“…To enable rapid propagation of action potentials, axons are ensheathed by myelin, a multilayered insulating membrane formed by oligodendrocytes. Most of the…”
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6
Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex
Published in eLife (05-08-2024)“…Like other volume electron microscopy approaches, automated tape-collecting ultramicrotomy (ATUM) enables imaging of serial sections deposited on thick plastic…”
Get full text
Journal Article -
7
Neurons on tape: Automated Tape Collecting Ultramicrotomy-mediated volume EM for targeting neuropathology
Published in Methods in cell biology (2023)“…In this chapter, we review Automated Tape Collecting Ultramicrotomy (ATUM), which, among other array tomography methods, substantially simplified large-scale…”
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A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice
Published in The Journal of experimental medicine (06-05-2024)“…Heterozygous mutations in the TBK1 gene can cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The majority of TBK1-ALS/FTD patients…”
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9
Combining array tomography with electron tomography provides insights into leakiness of the blood-brain barrier in mouse cortex
Published in eLife (05-08-2024)“…Like other volume electron microscopy approaches, automated tape-collecting ultramicrotomy (ATUM) enables imaging of serial sections deposited on thick plastic…”
Get full text
Journal Article