Search Results - "Kisiel, Walter"

The role of tissue factor pathway inhibitor-2 in cancer biology by Sierko, Ewa, Wojtukiewicz, Marek Z, Kisiel, Walter

“…Tissue factor pathway inhibitor-2 (TFPI-2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway…”
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Expression of tissue factor pathway inhibitor (TFPI) in human breast and colon cancer tissue by Sierko, Ewa, Wojtukiewicz, Marek Z, Zimnoch, Lech, Kisiel, Walter

“…Activation of blood coagulation, a phenomenon frequently observed in breast and colon cancer patients, contributes to tumour progression. The principal…”
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Granzyme M Is a Regulatory Protease That Inactivates Proteinase Inhibitor 9, an Endogenous Inhibitor of Granzyme B by Mahrus, Sami, Kisiel, Walter, Craik, Charles S.

“…Granzyme M is a trypsin-fold serine protease that is specifically found in the granules of natural killer cells. This enzyme has been implicated recently in…”
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Structure, function and biology of tissue factor pathway inhibitor-2 by Chand, Hitendra S, Foster, Donald C, Kisiel, Walter

“…Tissue factor pathway inhibitor-2 (TFPI-2) is a 32 kDa matrix-associated Kunitz-type serine proteinase inhibitor consisting of a short amino-terminal…”
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Co-localization of Protein Z, Protein Z-Dependent protease inhibitor and coagulation factor X in human colon cancer tissue: Implications for coagulation regulation on tumor cells by Sierko, Ewa, Wojtukiewicz, Marek Z, Zimnoch, Lech, Tokajuk, Piotr, Ostrowska-Cichocka, Krystyna, Kisiel, Walter

“…Abstract Introduction Several hemostatic system components, including factor X (FX), contribute to cancer progression. The Protein Z (PZ)/protein Z-dependent…”
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ADAMTS1 Interacts with, Cleaves, and Modifies the Extracellular Location of the Matrix Inhibitor Tissue Factor Pathway Inhibitor-2 by Torres-Collado, Antoni X., Kisiel, Walter, Iruela-Arispe, Maria L., Rodríguez-Manzaneque, Juan C.

“…ADAMTS1 is an extracellular metalloproteinase known to participate in a variety of biological processes that includes inflammation, angiogenesis, and…”
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Liver myofibroblasts activate protein C and respond to activated protein C by Gillibert-Duplantier, Jennifer, Rullier, Anne, Neaud, Véronique, Kisiel, Walter, Rosenbaum, Jean

“…AIM:To study the protein C activation system in human liver myofibroblasts,and the effects of activated protein C(APC)on these cells.METHODS:Human liver…”
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The coagulation cascade: initiation, maintenance, and regulation by Davie, Earl W, Fujikawa, Kazuo, Kisiel, Walter

“…There are two principal mechanisms to stop the loss of blood in higher organisms following vascular injury. The reactions set the stage for the coagulation…”
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Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model by Hofmann, Marion A., Lalla, Evanthia, Lu, Yan, Gleason, Michelle Ryu, Wolf, Bonnie M., Tanji, Nozomu, Ferran, Luis J., Kohl, Brigitte, Rao, Vijay, Kisiel, Walter, Stern, David M., Schmidt, Ann Marie

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Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues by Kempaiah, Prakasha, Chand, Hitendra S, Kisiel, Walter

“…Previous studies have shown that the expression of tissue factor pathway inhibitor-2 (TFPI-2), a matrix-associated Kunitz-type serine proteinase inhibitor, is…”
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Comparative effects of aprotinin and human recombinant R24K KD1 on temporal renal function in Long-Evans rats by Kempaiah, Prakasha, Danielson, Leslie A, Barry, Marc, Kisiel, Walter

“…Bovine aprotinin, a reversible inhibitor of plasmin and kallikrein, has been clinically approved for over two decades to prevent perioperative blood loss…”
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Structure-Function Analysis of the Reactive Site in the First Kunitz-type Domain of Human Tissue Factor Pathway Inhibitor-2 by Chand, Hitendra S., Schmidt, Amy E., Bajaj, S. Paul, Kisiel, Walter

“…Human tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type proteinase inhibitor that regulates a variety of serine proteinases involved in coagulation…”
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Hypoxia/Hypoxemia-Induced Activation of the Procoagulant Pathways and the Pathogenesis of Ischemia-Associated Thrombosis by Yan, Shi-Fang, Mackman, Nigel, Kisiel, Walter, Stern, David M, Pinsky, David J

“…Although oxygen deprivation has long been associated with triggering of the procoagulant pathway and venous thrombosis, blood hypoxemia and stasis by…”
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Immunohistochemical localization of tissue factor pathway inhibitor-2 in human tumor tissue by Wojtukiewicz, Marek Z, Sierko, Ewa, Zimnoch, Lech, Kozlowski, Leszek, Kisiel, Walter

“…The progression of neoplasms is frequently associated with thromboembolic complications. Coagulation proteins, particularly tissue factor (TF), have been shown…”
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Protein Z is present in human breast cancer tissue by SIERKO, Ewa, WOJTUKIEWICZ, Marek Z, ZIMNOCH, Lech, TOKAJUK, Piotr, KISIEL, Walter

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Tissue Factor Transcription Driven by Egr-1 is a Critical Mechanism of Murine Pulmonary Fibrin Deposition in Hypoxia by Yan, Shi-Fang, Zou, Yu Shan, Gao, Yun, Zhai, Chao, Mackman, Nigel, Lee, Stephen L., Milbrandt, Jeffrey, Pinsky, David, Kisiel, Walter, Stern, David

“…Local hypoxemia and stasis trigger thrombosis. We have demonstrated previously that in a murine model of normobaric hypoxia pulmonary fibrin deposition is a…”
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Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), in human glioma cells by KONDURI, Santhi D, SRIVENUGOPAL, Kalkunte S, LAKKA, Sajani S, RAO, Jasti S, YANAMANDRA, Niranjan, DINH, Dzung H, OLIVERO, William C, GUJRATI, Meena, FOSTER, Donald C, KISIEL, Walter, ALI-OSMAN, Francis, KONDRAGANTI, Shakuntala

“…We have shown previously that the tissue factor pathway inhibitor-2 (TFPI-2), a broad range proteinase inhibitor, is highly expressed in low-grade gliomas,…”
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Thrombin Up-regulates Tissue Factor Pathway Inhibitor-2 Synthesis through a Cyclooxygenase-2-dependent, Epidermal Growth Factor Receptor-independent Mechanism by Neaud, Véronique, Duplantier, Jennifer Gillibert, Mazzocco, Claire, Kisiel, Walter, Rosenbaum, Jean

“…The serine proteinase inhibitor tissue factor pathway inhibitor-2 (TFPI-2) inhibits the tissue factor-factor VIIa complex and thereby impairs factor Xa and…”
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Protein Z/protein Z-dependent protease inhibitor system in loco in human gastric cancer by Sierko, Ewa, Wojtukiewicz, Marek Z., Zimnoch, Lech, Tokajuk, Piotr, Ostrowska-Cichocka, Krystyna, Kisiel, Walter

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The serpin proteinase inhibitor 8: an endogenous furin inhibitor released from human platelets by Leblond, Julie, Laprise, Marie-Hélène, Gaudreau, Simon, Grondin, Francine, Kisiel, Walter, Dubois, Claire M

“…The cornerstone of hemostasis is the ability of the organism to limit the enzymatic processes involved, thereby avoiding thrombosis. For this, anticoagulant…”
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