Search Results - "Kisich, K O"

Antimycobacterial agent based on mRNA encoding human β-defensin 2 enables primary macrophages to restrict growth of Mycobacterium tuberculosis by KISICH, Kevin O, HEIFETS, Leonid, HIGGINS, Michael, DIAMOND, Gill

“…Human macrophages are hosts for Mycobacterium tuberculosis, the causative agent of tuberculosis, which killed approximately 1.87 million people in 1997. Human…”
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Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis by Kisich, K.O., Gelperina, S., Higgins, M.P., Wilson, S., Shipulo, E., Oganesyan, E., Heifets, L.

“…Macrophages in the lungs are the most important cell type supporting replication of Mycobacterium tuberculosis in humans. The objective of this study was to…”
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Antimicrobial peptides in the airway by Laube, D M, Yim, S, Ryan, L K, Kisich, K O, Diamond, G

“…The airway provides numerous defense mechanisms to prevent microbial colonization by the large numbers of bacteria and viruses present in ambient air. An…”
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Specific inhibition of macrophage TNF-alpha expression by in vivo ribozyme treatment by Kisich, K O, Malone, R W, Feldstein, P A, Erickson, K L

“…The overproduction of the cytokine TNF-alpha is associated with inflammatory and autoimmune diseases. We have developed a means to block TNF-alpha production…”
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Factors altering ribozyme-mediated cleavage of tumor necrosis factor-alpha mRNA in vitro by Kisich, K O, Freedland, S J, Erickson, K L

“…Hammerhead ribozymes are capable of cleaving RNA in a sequence specific manner in vitro. However, the complex environment of the cell differs dramatically from…”
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Near-critical fluid micronization of stabilized vaccines, antibiotics and anti-virals by Sievers, R.E., Quinn, B.P., Cape, S.P., Searles, J.A., Braun, C.S., Bhagwat, P., Rebits, L.G., McAdams, D.H., Burger, J.L., Best, J.A., Lindsay, L., Hernandez, M.T., Kisich, K.O., Iacovangelo, T., Kristensen, D., Chen, D.

“…Fine powder preparations of vaccines hold promise in resolving many issues encountered in the transport and delivery of vaccines such as loss of potency during…”
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Selective Killing of Vaccinia Virus by LL-37: Implications for Eczema Vaccinatum by Howell, Michael D, Jones, James F, Kisich, Kevin O, Streib, Joanne E, Gallo, Richard L, Leung, Donald Y. M

“…Possible bioterrorism with smallpox has led to the resumption of smallpox (vaccinia virus) immunization. One complication, eczema vaccinatum, occurs primarily…”
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Tumor Necrosis Factor Alpha Stimulates Killing of Mycobacterium tuberculosis by Human Neutrophils by KISICH, Kevin O, HIGGINS, Michael, DIAMOND, Gill, HEIFETS, Leonid

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Role for STAT5 in the Pathogenesis of IL-2-Induced Glucocorticoid Resistance by Goleva, Elena, Kisich, Kevin O, Leung, Donald Y. M

“…Glucocorticoids (GC) are highly effective in the control of diseases associated with T cell activation. However, a subset of individuals is GC insensitive…”
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Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis by KISICH, K. O, GELPERINA, S, HIGGINS, M. P, WILSON, S, SHIPULO, E, OGANESYAN, E, HEIFETS, L

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Serine-Arginine-rich Protein p30 Directs Alternative Splicing of Glucocorticoid Receptor Pre-mRNA to Glucocorticoid Receptor β in Neutrophils by Xu, Qing, Leung, Donald Y.M., Kisich, Kevin O.

“…Glucocorticoid (GC) insensitivity is a major clinical challenge in the treatment of many inflammatory diseases. It has been shown previously that GC…”
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Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype by Hauk, Pia J, Goleva, Elena, Strickland, Ian, Vottero, Alessandra, Chrousos, George P, Kisich, Kevin O, Leung, Donald Y M

“…Glucocorticoid (GC) insensitivity is a challenging clinical problem associated with many chronic inflammatory disorders and life-threatening disease…”
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Prevention of glucocorticoid receptor (GCR) nuclear translocation: A novel mechanism of IL-2-induced steroid resistance in T cells by Goleva, E., Kisich, K.O., Leung, D.Y.M.

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Increased propensity of atopic dermatitis (AD) patients to viral infections may be due to Th2 cytokines which down-regulate cathelicidins with anti-viral activity by Howell, M.D., Streib, J.E., Kisich, K.O., Jones, J.F., Gallo, R.L., Leung, D.Y.M.

“…Adverse reactions in AD patients have hindered efforts to vaccinate individuals against vaccinia virus (smallpox vaccine; VV). Previous studies by our group…”
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