Search Results - "Kishida, Ken"

Adiponectin as a routine clinical biomarker by Kishida, Ken, MD, PhD, Funahashi, Tohru, MD, PhD, Shimomura, Iichiro, MD, PhD

“…Adiponectin is a protein synthesized and secreted predominantly by adipocytes into the peripheral blood. However, circulating adiponectin level is inversely…”
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Visceral adiposity as a target for the management of the metabolic syndrome by Kishida, Ken, Funahashi, Tohru, Matsuzawa, Yuji, Shimomura, Iichiro

“…Atherosclerosis, the underlying cause of atherosclerotic cardiovascular disease (ACVD), develops due not only to a single cardiovascular risk factor but to a…”
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Absolute value of visceral fat area measured on computed tomography scans and obesity-related cardiovascular risk factors in large-scale Japanese general population (the VACATION-J study) by Hiuge-Shimizu, Aki, Kishida, Ken, Funahashi, Tohru, Ishizaka, Yuko, Oka, Rie, Okada, Minoru, Suzuki, Shizu, Takaya, Norihide, Nakagawa, Tohru, Fukui, Toshiki, Fukuda, Hiroshi, Watanabe, Naoya, Yoshizumi, Tohru, Nakamura, Tadashi, Matsuzawa, Yuji, Yamakado, Minoru, Shimomura, Iichiro

“…The management of cardiovascular risk factors is important for prevention of atherosclerotic cardiovascular diseases (ACVD). Visceral fat accumulation plays an…”
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Visualized macrophage dynamics and significance of S100A8 in obese fat by Sekimoto, Ryohei, Fukuda, Shiro, Maeda, Norikazu, Tsushima, Yu, Matsuda, Keisuke, Mori, Takuya, Nakatsuji, Hideaki, Nishizawa, Hitoshi, Kishida, Ken, Kikuta, Junichi, Maijima, Yumiko, Funahashi, Tohru, Ishii, Masaru, Shimomura, Iichiro

“…Chronic low-grade inflammation of adipose tissue plays a crucial role in the pathophysiology of obesity. Immunohistological microscopic analysis in obese fat…”
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Molecular mechanisms of diabetes and atherosclerosis: role of adiponectin by Kishida, Ken, Funahashi, Tohru, Shimomura, Iichiro

“…Type 2 diabetes mellitus (T2DM) is a disease characterized by inadequate beta-cell response due to progressive insulin resistance that typically accompanies…”
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Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages by KUMADA, Masahiro, KIHARA, Shinji, NAGASAWA, Azumi, FUNAHASHI, Tohru, MATSUZAWA, Yuji, OUCHI, Noriyuki, KOBAYASHI, Hideki, OKAMOTO, Yoshihisa, OHASHI, Koji, MAEDA, Kazuhisa, NAGARETANI, Hiroyuki, KISHIDA, Ken, MAEDA, Norikazu

“…Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin,…”
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PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein by MAEDA, Norikazu, TAKAHASHI, Masahiko, KURIYAMA, Hiroshi, HOTTA, Kikuko, NAKAMURA, Tadashi, SHIMOMURA, Iichiro, MATSUZAWA, Yuji, FUNAHASHI, Tohru, KIHARA, Shinji, NISHIZAWA, Hitoshi, KISHIDA, Ken, NAGARETANI, Hiroyuki, MATSUDA, Morihiro, KOMURO, Ryutaro, OUCHI, Noriyuki

“…PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein Norikazu Maeda , Masahiko Takahashi , Tohru Funahashi ,…”
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Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase by Hibuse, T, Maeda, N, Funahashi, T, Yamamoto, K, Nagasawa, A, Mizunoya, W, Kishida, K, Inoue, K, Kuriyama, H, Nakamura, T

“…In adipocytes, hydrolysis of triglycerides results in the release of free fatty acids and glycerol. Aquaporin 7 (AQP7), a member of aquaglyceroporins, is known…”
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Clinical significance of visceral adiposity assessed by computed tomography: A Japanese perspective by Ryo, Miwa, Kishida, Ken, Nakamura, Tadashi, Yoshizumi, Tohru, Funahashi, Tohru, Shimomura, Iichiro

“…Abdominal obesity,rather than total amount of fat,is linked to obesity-related disorders.Visceral adiposity is an important component of obesity-related…”
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Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein by NISHIZAWA, Hitoshi, SHIMOMURA, Iichiro, NAKAMURA, Tadashi, TOCHINO, Yoshihiro, FUNAHASHI, Tohru, MATSUZAWA, Yuji, KISHIDA, Ken, MAEDA, Norikazu, KURIYAMA, Hiroshi, NAGARETANI, Hiroyuki, MATSUDA, Morihiro, KONDO, Hidehiko, FURUYAMA, Naoki, KIHARA, Shinji

“…Androgens Decrease Plasma Adiponectin, an Insulin-Sensitizing Adipocyte-Derived Protein Hitoshi Nishizawa , Iichiro Shimomura , Ken Kishida , Norikazu Maeda ,…”
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Accumulation of adiponectin in inflamed adipose tissues of obese mice by Nakatsuji, Hideaki, Kishida, Ken, Sekimoto, Ryohei, Komura, Noriyuki, Kihara, Shinji, Funahashi, Tohru, Shimomura, Iichiro

“…Abstract Objective Adipose tissue inflammation plays an important role in the pathogenesis of obesity-associated complications, such as atherosclerosis…”
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Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages by OUCHI, Noriyuki, KIHARA, Shinji, HOTTA, Kikuko, MURAGUCHI, Masahiro, OHMOTO, Yasukazu, YAMASHITA, Shizuya, FUNAHASHI, Tohru, MATSUZAWA, Yuji, ARITA, Yukio, NISHIDA, Makoto, MATSUYAMA, Akifumi, OKAMOTO, Yoshihisa, ISHIGAMI, Masato, KURIYAMA, Hiroshi, KISHIDA, Ken, NISHIZAWA, Hitoshi

“…Excessive lipid accumulation in macrophages plays an important role in the development of atherosclerosis. Recently, we discovered an adipocyte-specific plasma…”
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Relationships between Circulating Adiponectin Levels and Fat Distribution in Obese Subjects by Kishida, Ken, Kim, Kyoung Kon, Funahashi, Tohru, Matsuzawa, Yuji, Kang, Hee-Cheol, Shimomura, Iichiro

“…Aim: Most studies have reported that circulating levels of adiponectin are negatively correlated with the body mass index (BMI), and hypoadiponectinemia is…”
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Tautomerism of Histidine 64 Associated with Proton Transfer in Catalysis of Carbonic Anhydrase by Shimahara, Hideto, Yoshida, Takuya, Shibata, Yasutaka, Shimizu, Masato, Kyogoku, Yoshimasa, Sakiyama, Fumio, Nakazawa, Takashi, Tate, Shin-ichi, Ohki, Shin-ya, Kato, Takeshi, Moriyama, Hozumi, Kishida, Ken-ichi, Tano, Yasuo, Ohkubo, Tadayasu, Kobayashi, Yuji

“…The imidazole 15N signals of histidine 64 (His64), involved in the catalytic function of human carbonic anhydrase II (hCAII), were assigned unambiguously. This…”
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Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue by Maeda, N, Funahashi, T, Hibuse, T, Nagasawa, A, Kishida, K, Kuriyama, H, Nakamura, T, Kihara, S, Shimomura, I, Matsuzawa, Y

“…Adipocytes hydrolyze triglycerides and secrete free fatty acids and glycerol into the circulation. The molecular mechanism involved in glycerol transport from…”
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Correlation between serum C1q-adiponectin/total adiponectin ratio and polyvascular lesions detected by vascular ultrasonography in Japanese type 2 diabetics by Hirata, Ayumu, Kishida, Ken, Kobayashi, Hironori, Nakatsuji, Hideaki, Funahashi, Tohru, Shimomura, Iichiro

“…Abstract Objective Atherosclerosis is a disease of blood vessels. Adiponectin is a biomarker of atherosclerosis. Adiponectin and C1q form a protein complex in…”
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Binding of adiponectin and C1q in human serum, and clinical significance of the measurement of C1q–adiponectin / total adiponectin ratio by Nakatsuji, Hideaki, Kobayashi, Hironori, Kishida, Ken, Nakagawa, Tohru, Takahashi, Shigeo, Tanaka, Hideaki, Akamatsu, Suguru, Funahashi, Tohru, Shimomura, Iichiro

“…Abstract Objective Adiponectin and C1q have similar sequences, exist abundantly in blood, and are produced by adipose tissues. The aim of this study was to…”
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Reciprocal regulation of natriuretic peptide receptors by insulin in adipose cells by Nakatsuji, Hideaki, Maeda, Norikazu, Hibuse, Toshiyuki, Hiuge, Aki, Hirata, Ayumu, Kuroda, Yohei, Kishida, Ken, Kihara, Shinji, Funahashi, Tohru, Shimomura, Iichiro

“…Atrial- and brain-type natriuretic peptides (ANP and BNP, respectively) have been shown to exert potent lipolytic action in adipocytes. A family of natriuretic…”
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Short-term intervention reduces bioelectrical impedance analysis-measured visceral fat in type 2 diabetes mellitus by Ryo, Miwa, Kishida, Ken, Nakamura, Tadashi, Funahashi, Tohru, Shimomura, Iichiro

“…Abstract In 25 patients with Type 2 diabetes mellitus, the short-term in-hospital calorie restriction combined with moderate exercise reduced visceral fat. The…”
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Sleep-wake cycle irregularities in type 2 diabetics by Nakanishi-Minami, Tomoko, Kishida, Ken, Funahashi, Tohru, Shimomura, Iichiro

“…The incidence of type 2 diabetes mellitus (T2DM) has been increasing in recent years. Sleep loss and circadian rhythm abnormalities are thought to be one of…”
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