Search Results - "Kiseok Jang"
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MicroRNA-130b functions as an oncogene and is a predictive marker of poor prognosis in lung adenocarcinoma
Published in Laboratory investigation (01-02-2021)“…Lung cancer is an aggressive disease and the leading cause of cancer-related deaths worldwide. In the past several decades, the incidence of adenocarcinoma has…”
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2
FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury
Published in Cell reports (Cambridge) (11-09-2018)“…Endoplasmic reticulum (ER) stress is associated with liver injury and fibrosis, and yet the hepatic factors that regulate ER stress-mediated inflammasome…”
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3
Infusion of Human Bone Marrow-Derived Mesenchymal Stem Cells Alleviates Autoimmune Nephritis in a Lupus Model by Suppressing Follicular Helper T-Cell Development
Published in Cell transplantation (2016)“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies to components of the cell nucleus. These…”
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4
Clinicopathologic features of rheumatoid nodules: a retrospective analysis
Published in Clinical rheumatology (01-11-2019)“…Objectives The clinical and histopathologic features of patients that have been diagnosed with rheumatoid nodules were investigated. Methods This study…”
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5
The loss of nuclear expression of single-stranded DNA binding protein 2 of gastric adenocarcinoma and its prognostic role: Analysis of molecular subtype
Published in PloS one (03-08-2020)“…Single-stranded DNA binding protein 2 (SSBP2) is ubiquitously expressed, with several studies reporting it to be a tumor suppressor. We investigated SSBP2…”
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6
Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis
Published in Scientific reports (12-03-2020)“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease linked to oxidative stress, which is associated with significant morbidity. The NADPH…”
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7
Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury?
Published in PloS one (28-09-2017)“…Previous studies have demonstrated protective effects of anti-receptor interacting protein kinase 1 (RIP1), a key necroptosis molecule. However, it is…”
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8
Mesothelin expression and its prognostic role according to microsatellite instability status in colorectal adenocarcinoma
Published in Medicine (Baltimore) (01-06-2019)“…The cell-surface glycoprotein, mesothelin, is normally present on mesothelial cells. Overexpression of mesothelin has been reported in many tumors and is…”
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9
Mycobacterium tuberculosis Rv2626c‐derived peptide as a therapeutic agent for sepsis
Published in EMBO molecular medicine (07-12-2020)“…The Rv2626c protein of Mycobacterium tuberculosis is a promising vaccine candidate owing to its strong serum antibody response in patients with tuberculosis…”
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10
Toxoplasma gondii GRA9 Regulates the Activation of NLRP3 Inflammasome to Exert Anti-Septic Effects in Mice
Published in International journal of molecular sciences (10-11-2020)“…Dense granule proteins (GRAs) are essential components in , which are suggested to be promising serodiagnostic markers in toxoplasmosis. In this study, we…”
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11
Bach2 deficiency leads autoreactive B cells to produce IgG autoantibodies and induce lupus through a T cell-dependent extrafollicular pathway
Published in Experimental & molecular medicine (09-12-2019)“…Class-switched IgG autoantibodies but not unswitched IgM autoantibodies play a crucial role in the development of systemic lupus erythematosus (SLE). Bach2 is…”
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12
Design and Fabrication of a Thin-Walled Free-Form Scaffold on the Basis of Medical Image Data and a 3D Printed Template: Its Potential Use in Bile Duct Regeneration
Published in ACS applied materials & interfaces (12-04-2017)“…Three-dimensional (3D) printing, combined with medical imaging technologies, such as computed tomography and magnetic resonance imaging (MRI), has shown a…”
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13
Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα
Published in PLoS pathogens (01-01-2017)“…Tuberculosis is a global health problem and at least one-third of the world's population is infected with Mycobacterium tuberculosis (MTB). MTB is a successful…”
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14
Shear Wave Elastography for Assessment of Steatohepatitis and Hepatic Fibrosis in Rat Models of Non-Alcoholic Fatty Liver Disease
Published in Ultrasound in medicine & biology (01-12-2015)“…Abstract The purpose of this study was to evaluate shear wave elastography (SWE) as a method for determining the severity of non-alcoholic fatty liver disease…”
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15
Rifamycin O, An Alternative Anti- Mycobacterium abscessus Agent
Published in Molecules (Basel, Switzerland) (31-03-2020)“…is the most difficult-to-treat nontuberculous mycobacteria because of its resistance to many antibiotics. In this study, we screened the Korea Chemical Bank…”
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16
Association of Microbial Dysbiosis with Gallbladder Diseases Identified by Bile Microbiome Profiling
Published in Journal of Korean medical science (19-07-2021)“…BACKGROUNDCholecystitis is an important risk factor for gallbladder cancer, but the bile microbiome and its association with gallbladder disease has not been…”
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17
Dietary schizophyllan reduces mitochondrial damage by activating SIRT3 in mice
Published in Archives of pharmacal research (01-04-2020)“…Schizophyllan (SPG), produced by Schizophyllum commune , is an exopolysaccharide with multiple academic and commercial uses, including in the food industry and…”
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Loss of YY1 expression predicts unfavorable prognosis in stage III colorectal cancer
Published in Indian journal of pathology & microbiology (01-06-2021)“…Background: Yin Yang 1 (YY1), the multifunctional transcription factor, has recently been assigned biological properties related to human malignancies. YY1 can…”
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Single-stranded DNA binding protein 2 expression is associated with patient survival in hepatocellular carcinoma
Published in BMC cancer (12-12-2018)“…SSBP2, single-stranded DNA binding protein 2, is a subunit of the ssDNA-binding complex that is involved in the maintenance of genome stability. The majority…”
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The Use of Foxa2-Overexpressing Adipose Tissue-Derived Stem Cells in a Scaffold System Attenuates Acute Liver Injury
Published in Gut and liver (15-03-2019)“…For the clinical application of stem cell therapy, functional enhancement is needed to increase the survival rate and the engraftment rate. The purpose of this…”
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