Search Results - "Kisand, K."

New insights into the natural course of knee osteoarthritis: early regulation of cytokines and growth factors, with emphasis on sex-dependent angiogenesis and tissue remodeling. A pilot study by Kisand, K., Tamm, A.E., Lintrop, M., Tamm, A.O.

“…This study was conducted to identify cytokine profiles associated with radiographic phenotypes of knee osteoarthritis (rKOA) with a focus on early stage of the…”
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PO.7.161 Clinical and immunological characterization of systemic lupus erythematosus (SLE) patients in estonia. A prospective cohort study of 40 SLE patients in estonia by Meisalu, S, Kisand, K

“…BackgroundSLE is a rare chronic autoimmune disease with polymorphic clinical manifestation and wide-ranging disease course with treatment tactics dependent on…”
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Increased microRNA‐323‐3p in IL‐22/IL‐17‐producing T cells and asthma: a role in the regulation of the TGF‐β pathway and IL‐22 production by Kärner, J., Wawrzyniak, M., Tankov, S., Runnel, T., Aints, A., Kisand, K., Altraja, A., Kingo, K., Akdis, C. A., Akdis, M., Rebane, A.

“…Background IL‐22‐ and IL‐17‐producing T cells have important roles in allergic diseases. MicroRNAs (miRNAs) are posttranscriptional regulators of gene…”
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Increased microRNA-323-3p in IL-22/IL-17-producing T cells and asthma: a role in the regulation of the TGF-[beta] pathway and IL-22 production by Karner, J, Wawrzyniak, M, Tankov, S, Runnel, T, Aints, A, Kisand, K, Altraja, A, Kingo, K, Akdis, C A, Akdis, M, Rebane, A

“…Background IL-22- and IL-17-producing T cells have important roles in allergic diseases. MicroRNAs (miRNAs) are posttranscriptional regulators of gene…”
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Anti-Cytokine Autoantibodies Preceding Onset of Autoimmune Polyendocrine Syndrome Type I Features in Early Childhood by Wolff, A. S. B., Sarkadi, A. K., Maródi, L., Kärner, J., Orlova, E., Oftedal, B. E. V., Kisand, K., Oláh, É., Meloni, A., Myhre, A. G., Husebye, E. S., Motaghedi, R., Perheentupa, J., Peterson, P., Willcox, N., Meager, A.

“…Purpose Almost all patients with autoimmune polyendocrine syndrome (APS)-I have high titer neutralizing autoantibodies to type I interferons (IFN), especially…”
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Interferon and Interferon‐Inducible Gene Activation in Patients with Type 1 Diabetes by Panarina, M., Kisand, K., Alnek, K., Heilman, K., Peet, A., Uibo, R.

“…Type 1 diabetes (T1D) is an autoimmune disease that is thought to be triggered by environmental factors in genetically susceptible individuals. Enteroviruses…”
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Anti‐cytokine autoantibodies suggest pathogenetic links with autoimmune regulator deficiency in humans and mice by Kärner, J., Meager, A., Laan, M., Maslovskaja, J., Pihlap, M., Remm, A., Juronen, E., Wolff, A. S. B., Husebye, E. S., Podkrajšek, K. T., Bratanic, N., Battelino, T., Willcox, N., Peterson, P., Kisand, K.

“…Summary Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a recessive disorder resulting from mutations in the autoimmune regulator…”
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Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis by Kerkhof, H.J.M, Doherty, M, Arden, N.K, Abramson, S.B, Attur, M, Bos, S.D, Cooper, C, Dennison, E.M, Doherty, S.A, Evangelou, E, Hart, D.J, Hofman, A, Javaid, K, Kerna, I, Kisand, K, Kloppenburg, M, Krasnokutsky, S, Maciewicz, R.A, Meulenbelt, I, Muir, K.R, Rivadeneira, F, Samuels, J, Sezgin, M, Slagboom, E, Smith, A.J.P, Spector, T.D, Tamm, A, Uitterlinden, A.G, Wheeler, M, Zhai, G, Zhang, W, van Meurs, J.B.J, Valdes, A.M

“…Summary Objective To clarify the role of common genetic variation in the Interleukin-1β ( IL1B ) and Interleukin-1R antagonist ( IL1RN ) genes on risk of knee…”
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S12.2 Type I interferons and their autoantibodies in the context of systemic lupus erythematosus by Haljasmägi, L, Bradford, H, Menon, M, Peterson, P, Vanker, M, Wincup, C, Bondet, V, Duffy, D, Isenberg, D, Kisand, K, Mauri, C

“…PurposeType I IFNs and their autoantibodies are implicated in the pathogenesis of Systemic lupus erythematosus (SLE), but their incidence and importance is…”
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Differences in B7 and CD28 family gene expression in the peripheral blood between newly diagnosed young-onset and adult-onset type 1 diabetes patients by Pruul, K., Kisand, K., Alnek, K., Metsküla, K., Reimand, K., Heilman, K., Peet, A., Varik, K., Peetsalu, M., Einberg, Ü., Tillmann, V., Uibo, R.

“…•The inhibitory CD80-CTLA4 pathway is activated in young-onset T1D.•The stimulatory CD86-CD28 pathway is dominant in adult-onset T1D.•These data emphasize…”
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A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis by Valdes, A.M, Arden, N.K, Tamm, A, Kisand, K, Doherty, S, Pola, E, Cooper, C, Muir, K.R, Kerna, I, Hart, D, O'Neil, F, Zhang, W, Spector, T.D, Maciewicz, R.A, Doherty, M

“…Summary Objective Interleukin-6 is a pro-inflammatory cytokine involved in the pathogenesis of osteoarthritis (OA). We investigated the role of two single…”
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Cytotoxic T-lymphocyte antigen 4 gene polymorphisms are associated with latent autoimmune diabetes in adults by Douroudis, K., Prans, E., Kisand, K., Nemvalts, V., Uibo, R.

“…Cytotoxic T lymphocyte antigen-4 (CTLA-4) molecule is an important regulator of T cell activation involved in the down-regulation of immune response…”
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Missense single nucleotide polymorphism of the ADAM12 gene is associated with radiographic knee osteoarthritis in middle-aged Estonian cohort by Kerna, I, Kisand, K, Tamm, A.E, Lintrop, M, Veske, K, Tamm, A.O

“…Summary Objective One of the recognized candidate genes of osteoarthritis (OA) is the ADAM metallopeptidase domain 12 (meltrin alpha) gene. We investigated the…”
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Flow Cytometry Study of Blood Cell Subtypes Reflects Autoimmune and Inflammatory Processes in Autoimmune Polyendocrine Syndrome Type I by Wolff, A.S.B, Oftedal, B.E.V, Kisand, K, Ersvær, E, Lima, K, Husebye, E.S

“…Autoimmune polyendocrine syndrome type I (APS I) is a recessive disorder caused by mutations in the autoimmune regulator (AIRE) gene. AIRE is expressed in…”
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386 ASSOCIATION OF METALLOPEPTIDASE DOMAIN 12 (ADAM12) GENE POLYMORPHISMS AND ADAM12 PROTEIN WITH THE DEVELOPMENT OF KNEE OSTEOARTHRITIS by Kerna, I, Kisand, K, Laitinen, P, Tamm, A

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Association of ADAM12-S protein with radiographic features of knee osteoarthritis and bone and cartilage markers by Kerna, I., Kisand, K., Laitinen, P., Tamm, A. E., Kumm, J., Lintrop, M., Tamm, A. O.

“…ADAM12 (A disintegrin and metalloprotease) is one of the candidate genes demonstrating susceptibility to osteoarthritis. The purpose of this study was to…”
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Low serum concentrations of serum vegf-r2 in elderly females with thumb base osteoarthritis: the ages-reykjavik study by Jonsson, H, Aspelund, T, Eiriksdottir, G, Tamm, A, Kisand, K, Franzson, L, Hauksdottir, A.M, Harris, T.B, Lenore Launer, L, Gudnason, V

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131 IMPACT OF CRYOPRESERVATION ON SERUM CONCENTRATION OF BIOMARKERS MMP-7 TIMP-1 VEGF AND VEGF-R2 IN BIOBANK by Kisand, K, Alnek, K, Krjukova, J, Kerna, I, Kumm, J, Jonsson, H, Tamm, A.O

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Oxidative stress in leucocytospermic prostatitis patients: preliminary results by Kullisaar, T., Türk, S., Punab, M., Korrovits, P., Kisand, K., Rehema, A., Zilmer, K., Zilmer, M., Mändar, R.

“…Summary The aim of this study was to contribute to the knowledge concerning pathogenesis of inflammatory chronic prostatitis by revealing possible shifts in…”
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The follow-up of asymptomatic persons with antibodies to pyruvate dehydrogenase in adult population samples by Kisand, K E, Metsküla, K, Kisand, K V, Kivik, T, Gershwin, M E, Uibo, R

“…The presence of antimitochondrial antibodies (AMA), the hallmark of primary biliary cirrhosis (PBC), precedes the clinical manifestation of the disease for…”
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