Search Results - "Kirszenblat, Leonie"

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  1. 1

    A Paradoxical Kind of Sleep in Drosophila melanogaster by Tainton-Heap, Lucy A.L., Kirszenblat, Leonie C., Notaras, Eleni T., Grabowska, Martyna J., Jeans, Rhiannon, Feng, Kai, Shaw, Paul J., van Swinderen, Bruno

    Published in Current biology (08-02-2021)
    “…The dynamic nature of sleep in many animals suggests distinct stages that serve different functions. Genetic sleep induction methods in animal models provide a…”
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    Journal Article
  2. 2

    Down-regulation of a cytokine secreted from peripheral fat bodies improves visual attention while reducing sleep in Drosophila by Ertekin, Deniz, Kirszenblat, Leonie, Faville, Richard, van Swinderen, Bruno

    Published in PLoS biology (03-08-2020)
    “…Sleep is vital for survival. Yet under environmentally challenging conditions, such as starvation, animals suppress their need for sleep. Interestingly,…”
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  3. 3

    The two‐component histidine kinases DrkA and SlnA are required for in vivo growth in the human pathogen Penicillium marneffei by Boyce, Kylie J., Schreider, Lena, Kirszenblat, Leonie, Andrianopoulos, Alex

    Published in Molecular microbiology (01-12-2011)
    “…Summary In order to cause disease fungal pathogens must be capable of evading or tolerating the host immune defence system. One commonly utilized evasion…”
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  4. 4

    LIN-44/Wnt directs dendrite outgrowth through LIN-17/Frizzled in C. elegans Neurons by Kirszenblat, Leonie, Pattabiraman, Divya, Hilliard, Massimo A

    Published in PLoS biology (01-09-2011)
    “…Nervous system function requires proper development of two functional and morphological domains of neurons, axons and dendrites. Although both these domains…”
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  5. 5

    The Yin and Yang of Sleep and Attention by Kirszenblat, Leonie, van Swinderen, Bruno

    Published in Trends in neurosciences (Regular ed.) (01-12-2015)
    “…Sleep is not a single state, but a complex set of brain processes that supports several physiological needs. Sleep deprivation is known to affect attention in…”
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  6. 6

    Visual experience drives sleep need in Drosophila by Kirszenblat, Leonie, Yaun, Rebecca, van Swinderen, Bruno

    Published in Sleep (New York, N.Y.) (01-07-2019)
    “…Sleep optimizes waking behavior, however, waking experience may also influence sleep. We used the fruit fly Drosophila melanogaster to investigate the…”
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  7. 7

    A dynamic deep sleep stage in Drosophila by van Alphen, Bart, Yap, Melvyn H W, Kirszenblat, Leonie, Kottler, Benjamin, van Swinderen, Bruno

    Published in The Journal of neuroscience (17-04-2013)
    “…How might one determine whether simple animals such as flies sleep in stages? Sleep in mammals is a dynamic process involving different stages of sleep…”
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  8. 8

    Sleep Restores Behavioral Plasticity to Drosophila Mutants by Dissel, Stephane, Angadi, Veena, Kirszenblat, Leonie, Suzuki, Yasuko, Donlea, Jeff, Klose, Markus, Koch, Zachary, English, Denis, Winsky-Sommerer, Raphaelle, van Swinderen, Bruno, Shaw, Paul J.

    Published in Current biology (18-05-2015)
    “…Given the role that sleep plays in modulating plasticity, we hypothesized that increasing sleep would restore memory to canonical memory mutants without…”
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  9. 9

    Sleep regulates visual selective attention in Drosophila by Kirszenblat, Leonie, Ertekin, Deniz, Goodsell, Joseph, Zhou, Yanqiong, Shaw, Paul J, van Swinderen, Bruno

    Published in Journal of experimental biology (14-12-2018)
    “…Although sleep deprivation is known to impair attention in humans and other mammals, the underlying reasons are not well understood, and whether similar…”
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  10. 10

    A conserved role for sleep in supporting Spatial Learning in Drosophila by Melnattur, Krishna, Kirszenblat, Leonie, Morgan, Ellen, Militchin, Valentin, Sakran, Blake, English, Denis, Patel, Rushi, Chan, Dorothy, van Swinderen, Bruno, Shaw, Paul J

    Published in Sleep (New York, N.Y.) (01-03-2021)
    “…Abstract Sleep loss and aging impair hippocampus-dependent Spatial Learning in mammalian systems. Here we use the fly Drosophila melanogaster to investigate…”
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  11. 11

    A dominant mutation in mec-7/β-tubulin affects axon development and regeneration in Caenorhabditis elegans neurons by Kirszenblat, Leonie, Neumann, Brent, Coakley, Sean, Hilliard, Massimo A

    Published in Molecular biology of the cell (01-02-2013)
    “…Microtubules have been known for decades to be basic elements of the cytoskeleton. They form long, dynamic, rope-like structures within the cell that are…”
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  12. 12

    Closed-Loop Behavioral Control Increases Coherence in the Fly Brain by Paulk, Angelique C, Kirszenblat, Leonie, Zhou, Yanqiong, van Swinderen, Bruno

    Published in The Journal of neuroscience (15-07-2015)
    “…A crucial function of the brain is to be able to distinguish whether or not changes in the environment are caused by one's own actions. Even the smallest…”
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  13. 13

    Neurexin-1 regulates sleep and synaptic plasticity in Drosophila melanogaster by Larkin, Aoife, Chen, Ming-Yu, Kirszenblat, Leonie, Reinhard, Judith, van Swinderen, Bruno, Claudianos, Charles

    Published in The European journal of neuroscience (01-10-2015)
    “…Neurexins are cell adhesion molecules that are important for synaptic plasticity and homeostasis, although links to sleep have not yet been investigated. We…”
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  14. 14

    Transient Dysregulation of Dopamine Signaling in a Developing Drosophila Arousal Circuit Permanently Impairs Behavioral Responsiveness in Adults by Ferguson, Lachlan, Petty, Alice, Rohrscheib, Chelsie, Troup, Michael, Kirszenblat, Leonie, Eyles, Darryl W, van Swinderen, Bruno

    Published in Frontiers in psychiatry (13-02-2017)
    “…The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the…”
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  15. 15