Search Results - "Kirszenblat, Leonie"
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A Paradoxical Kind of Sleep in Drosophila melanogaster
Published in Current biology (08-02-2021)“…The dynamic nature of sleep in many animals suggests distinct stages that serve different functions. Genetic sleep induction methods in animal models provide a…”
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2
Down-regulation of a cytokine secreted from peripheral fat bodies improves visual attention while reducing sleep in Drosophila
Published in PLoS biology (03-08-2020)“…Sleep is vital for survival. Yet under environmentally challenging conditions, such as starvation, animals suppress their need for sleep. Interestingly,…”
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The two‐component histidine kinases DrkA and SlnA are required for in vivo growth in the human pathogen Penicillium marneffei
Published in Molecular microbiology (01-12-2011)“…Summary In order to cause disease fungal pathogens must be capable of evading or tolerating the host immune defence system. One commonly utilized evasion…”
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LIN-44/Wnt directs dendrite outgrowth through LIN-17/Frizzled in C. elegans Neurons
Published in PLoS biology (01-09-2011)“…Nervous system function requires proper development of two functional and morphological domains of neurons, axons and dendrites. Although both these domains…”
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5
The Yin and Yang of Sleep and Attention
Published in Trends in neurosciences (Regular ed.) (01-12-2015)“…Sleep is not a single state, but a complex set of brain processes that supports several physiological needs. Sleep deprivation is known to affect attention in…”
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6
Visual experience drives sleep need in Drosophila
Published in Sleep (New York, N.Y.) (01-07-2019)“…Sleep optimizes waking behavior, however, waking experience may also influence sleep. We used the fruit fly Drosophila melanogaster to investigate the…”
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A dynamic deep sleep stage in Drosophila
Published in The Journal of neuroscience (17-04-2013)“…How might one determine whether simple animals such as flies sleep in stages? Sleep in mammals is a dynamic process involving different stages of sleep…”
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8
Sleep Restores Behavioral Plasticity to Drosophila Mutants
Published in Current biology (18-05-2015)“…Given the role that sleep plays in modulating plasticity, we hypothesized that increasing sleep would restore memory to canonical memory mutants without…”
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9
Sleep regulates visual selective attention in Drosophila
Published in Journal of experimental biology (14-12-2018)“…Although sleep deprivation is known to impair attention in humans and other mammals, the underlying reasons are not well understood, and whether similar…”
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A conserved role for sleep in supporting Spatial Learning in Drosophila
Published in Sleep (New York, N.Y.) (01-03-2021)“…Abstract Sleep loss and aging impair hippocampus-dependent Spatial Learning in mammalian systems. Here we use the fly Drosophila melanogaster to investigate…”
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11
A dominant mutation in mec-7/β-tubulin affects axon development and regeneration in Caenorhabditis elegans neurons
Published in Molecular biology of the cell (01-02-2013)“…Microtubules have been known for decades to be basic elements of the cytoskeleton. They form long, dynamic, rope-like structures within the cell that are…”
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12
Closed-Loop Behavioral Control Increases Coherence in the Fly Brain
Published in The Journal of neuroscience (15-07-2015)“…A crucial function of the brain is to be able to distinguish whether or not changes in the environment are caused by one's own actions. Even the smallest…”
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13
Neurexin-1 regulates sleep and synaptic plasticity in Drosophila melanogaster
Published in The European journal of neuroscience (01-10-2015)“…Neurexins are cell adhesion molecules that are important for synaptic plasticity and homeostasis, although links to sleep have not yet been investigated. We…”
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14
Transient Dysregulation of Dopamine Signaling in a Developing Drosophila Arousal Circuit Permanently Impairs Behavioral Responsiveness in Adults
Published in Frontiers in psychiatry (13-02-2017)“…The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the…”
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15
Wnt signals and Frizzled receptors regulate dendrite formation in C. elegans
Published in Neuroscience research (01-09-2011)Get full text
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