Search Results - "Kirsh, Sarah M"
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Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
Published in BMC cancer (01-06-2023)“…Neuropeptide Y (NPY) is an abundant neurohormone in human breast carcinomas that acts on a class of G-protein coupled receptors, of which NPY1R and NPY5R are…”
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Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation
Published in The Journal of biological chemistry (01-03-2022)“…Neuropeptide Y (NPY) is an abundant neurohormone in the central and peripheral nervous system involved in feeding behavior, energy balance, nociception, and…”
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Spheroids as a 3D Model of the Hypoxic Tumor Microenvironment
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Spheroids enable the study of tumors and tumor hypoxia using a more representative model of the physiological environment compared to 2D cell culture…”
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