Search Results - "Kirsch, Martina"

Single chain Fab (scFab) fragment by Hust, Michael, Jostock, Thomas, Menzel, Christian, Voedisch, Bernd, Mohr, Anja, Brenneis, Mariam, Kirsch, Martina I, Meier, Doris, Dübel, Stefan

“…The connection of the variable part of the heavy chain (VH) and and the variable part of the light chain (VL) by a peptide linker to form a consecutive…”
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The effects of single nucleotide polymorphisms in glutamatergic neurotransmission genes on neural response to alcohol cues and craving by Bach, Patrick, Kirsch, Martina, Hoffmann, Sabine, Jorde, Anne, Mann, Karl, Frank, Josef, Charlet, Katrin, Beck, Anne, Heinz, Andreas, Walter, Henrik, Rietschel, Marcella, Kiefer, Falk, Vollstädt‐Klein, Sabine

“…The aim of the current study was to determine genotype effects of four single nucleotide polymorphisms (SNPs) in the genes of the N‐Methyl‐d‐aspartate receptor…”
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Genetic Variation in the Atrial Natriuretic Peptide Transcription Factor GATA4 Modulates Amygdala Responsiveness in Alcohol Dependence by Jorde, Anne, Bach, Patrick, Witt, Stephanie H, Becker, Kathleen, Reinhard, Iris, Vollstädt-Klein, Sabine, Kirsch, Martina, Hermann, Derik, Charlet, Katrin, Beck, Anne, Wimmer, Lioba, Frank, Josef, Treutlein, Jens, Spanagel, Rainer, Mann, Karl, Walter, Henrik, Heinz, Andreas, Rietschel, Marcella, Kiefer, Falk

“…Background Two genome-wide association studies recently showed alcohol dependence to be associated with a single-nucleotide polymorphism (rs13273672) located…”
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The SyBil-AA real-time fMRI neurofeedback study: protocol of a single-blind randomized controlled trial in alcohol use disorder by Gerchen, Martin Fungisai, Kirsch, Martina, Bahs, Nathalie, Halli, Patrick, Gerhardt, Sarah, Schäfer, Axel, Sommer, Wolfgang H, Kiefer, Falk, Kirsch, Peter

“…Alcohol Use Disorder is a highly prevalent mental disorder which puts a severe burden on individuals, families, and society. The treatment of Alcohol Use…”
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Development of human antibody fragments using antibody phage display for the detection and diagnosis of Venezuelan equine encephalitis virus (VEEV) by Kirsch, Martina Inga, Hülseweh, Birgit, Nacke, Christoph, Rülker, Torsten, Schirrmann, Thomas, Marschall, Hans-Jürgen, Hust, Michael, Dübel, Stefan

“…Venezuelan equine encephalitis virus (VEEV) belongs to the Alphavirus group. Several species of this family are also pathogenic to humans and are recognized as…”
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Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus by Schütte, Mark, Thullier, Philippe, Pelat, Thibaut, Wezler, Xenia, Rosenstock, Philip, Hinz, Dominik, Kirsch, Martina Inga, Hasenberg, Mike, Frank, Ronald, Schirrmann, Thomas, Gunzer, Matthias, Hust, Michael, Dübel, Stefan

“…Aspergillus fumigatus is a common airborne fungal pathogen for humans. It frequently causes an invasive aspergillosis (IA) in immunocompromised patients with…”
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Real-time functional magnetic resonance imaging neurofeedback can reduce striatal cue-reactivity to alcohol stimuli by Kirsch, Martina, Gruber, Isabella, Ruf, Matthias, Kiefer, Falk, Kirsch, Peter

“…It has been shown that in alcoholic patients, alcohol‐related cues produce increased activation of reward‐related brain regions like the ventral striatum (VS),…”
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Dynamic frontostriatal functional peak connectivity (in alcohol use disorder) by Gerchen, Martin Fungisai, Weiss, Franziska, Kirsch, Martina, Rentsch, Alena, Halli, Patrick, Kiefer, Falk, Kirsch, Peter

“…Alcohol use disorder (AUD) is associated with changes in frontostriatal connectivity, but functional magnetic resonance imaging (fMRI) functional connectivity…”
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Cerebellar and hippocampal activation during eyeblink conditioning depends on the experimental paradigm: a MEG study by Kirsch, Peter, Achenbach, Caroline, Kirsch, Martina, Heinzmann, Matthias, Schienle, Anne, Vaitl, Dieter

“…The cerebellum and the hippocampus are key structures for the acquisition of conditioned eyeblink responses. Whereas the cerebellum seems to be crucial for all…”
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Cue-exposure treatment influences resting-state functional connectivity—a randomized controlled fMRI study in alcohol use disorder by Farré-Colomés, Àlvar, Tan, Haoye, Gerhardt, Sarah, Gerchen, Martin Fungisai, Kirsch, Martina, Hoffmann, Sabine, Kirsch, Peter, Kiefer, Falk, Vollstädt-Klein, Sabine

“…Rationale Cue-exposure therapy (CET) consists of exposing patients to the cause of their affliction in a controlled environment and after psychological…”
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Investigation of brain functional connectivity to assess cognitive control over cue‐processing in Alcohol Use Disorder by Strosche, Alicia, Zhang, Xiaochu, Kirsch, Martina, Hermann, Derik, Ende, Gabriele, Kiefer, Falk, Vollstädt‐Klein, Sabine

“…Alcohol Use Disorder has been associated with impairments of functional connectivity between neural networks underlying reward processing and cognitive…”
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Striatal activation and frontostriatal connectivity during non‐drug reward anticipation in alcohol dependence by Becker, Alena, Kirsch, Martina, Gerchen, Martin Fungisai, Kiefer, Falk, Kirsch, Peter

“…According to prevailing neurobiological theories of addiction, altered function in neural reward circuitry is a central mechanism of alcohol dependence…”
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Shifts in the functional topography of frontal cortex‐striatum connectivity in alcohol use disorder by Gerchen, Martin Fungisai, Rentsch, Alena, Kirsch, Martina, Kiefer, Falk, Kirsch, Peter

“…Frontostriatal circuits are centrally involved in the selection of behavioral programs and play a prominent role in alcohol use disorder (AUD) as well as other…”
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Effects of Cue-Exposure Treatment on Neural Cue Reactivity in Alcohol Dependence: A Randomized Trial by Vollstädt-Klein, Sabine, Loeber, Sabine, Kirsch, Martina, Bach, Patrick, Richter, Anne, Bühler, Mira, von der Goltz, Christoph, Hermann, Derik, Mann, Karl, Kiefer, Falk

“…Background In alcohol-dependent patients, alcohol-associated cues elicit brain activation in mesocorticolimbic networks involved in relapse mechanisms…”
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Striatal reward sensitivity predicts therapy-related neural changes in alcohol addiction by Becker, Alena, Gerchen, Martin Fungisai, Kirsch, Martina, Hoffmann, Sabine, Kiefer, Falk, Kirsch, Peter

“…Individual differences in reward sensitivity along with weakened executive control are characteristic for alcohol use disorder (AUD). Emerging translational…”
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Effects of d-cycloserine on extinction of mesolimbic cue reactivity in alcoholism: a randomized placebo-controlled trial by Kiefer, Falk, Kirsch, Martina, Bach, Patrick, Hoffmann, Sabine, Reinhard, Iris, Jorde, Anne, von der Goltz, Christoph, Spanagel, Rainer, Mann, Karl, Loeber, Sabine, Vollstädt-Klein, Sabine

“…Rationale Mesocorticolimbic reactivity to alcohol-associated cues has been shown to be associated with relapse to renewed drinking and to be decreased by…”
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A human scFv antibody generation pipeline for proteome research by Hust, Michael, Meyer, Torsten, Voedisch, Bernd, Rülker, Torsten, Thie, Holger, El-Ghezal, Aymen, Kirsch, Martina Inga, Schütte, Mark, Helmsing, Saskia, Meier, Doris, Schirrmann, Thomas, Dübel, Stefan

“…The functional decryption of the human proteome is the challenge which follows the sequencing of the human genome. Specific binders to every human protein are…”
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Validating incentive salience with functional magnetic resonance imaging: association between mesolimbic cue reactivity and attentional bias in alcohol-dependent patients by Vollstädt-Klein, Sabine, Loeber, Sabine, Richter, Anne, Kirsch, Martina, Bach, Patrick, von der Goltz, Christoph, Hermann, Derik, Mann, Karl, Kiefer, Falk

“…ABSTRACT Alcohol‐associated cues are able to elicit brain activations in mesocorticolimbic networks that are related to the rewarding properties of the drug…”
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Real-time functional magnetic resonance imaging neurofeedback can reduce striatal cue-reactivity to alcohol stimuli: Neurofeedback in addiction by Kirsch, Martina, Gruber, Isabella, Ruf, Matthias, Kiefer, Falk, Kirsch, Peter

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Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk by Bach, Patrick, Zois, Evangelos, Vollstädt‐Klein, Sabine, Kirsch, Martina, Hoffmann, Sabine, Jorde, Anne, Frank, Josef, Charlet, Katrin, Treutlein, Jens, Beck, Anne, Heinz, Andreas, Walter, Henrik, Rietschel, Marcella, Kiefer, Falk

“…Alcohol metabolizing enzymes, such as the alcohol dehydrogenases and the aldehyde dehydrogenases, regulate the levels of acetaldehyde in the blood and play an…”
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