Search Results - "Kirkwood, Phoebe"
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RISING STARS: Androgens and immune cell function
Published in Journal of endocrinology (01-06-2024)“…Androgens can modulate immune cell function and may contribute to differences in the prevalence and severity of common inflammatory conditions. Although most…”
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Journal Article -
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Single‐cell RNA sequencing redefines the mesenchymal cell landscape of mouse endometrium
Published in The FASEB journal (01-04-2021)“…The endometrium is a dynamic tissue that exhibits remarkable resilience to repeated episodes of differentiation, breakdown, regeneration, and remodeling…”
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Journal Article -
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Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation
Published in eLife (16-12-2022)“…The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of…”
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Evidence for a dynamic role for mononuclear phagocytes during endometrial repair and remodelling
Published in Scientific reports (09-11-2016)“…In women, endometrial breakdown, which is experienced as menstruation, is characterised by high concentrations of inflammatory mediators and immune cells which…”
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Journal Article -
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A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization
Published in Frontiers in endocrinology (Lausanne) (16-11-2022)“…Decidualization is the hormone-dependent process of endometrial remodeling that is essential for fertility and reproductive health. It is characterized by…”
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Mechanisms of Scarless Repair at Time of Menstruation: Insights From Mouse Models
Published in Frontiers in reproductive health (06-01-2022)“…The human endometrium is a remarkable tissue which may experience up to 400 cycles of hormone-driven proliferation, differentiation and breakdown during a…”
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Journal Article -
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Androgens regulate scarless repair of the endometrial “wound” in a mouse model of menstruation
Published in The FASEB journal (01-08-2016)“…ABSTRACT The human endometrium undergoes regular cycles of synchronous tissue shedding (wounding) and repair that occur during menstruation before…”
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The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair
Published in Science immunology (19-11-2021)“…Alveolar macrophages are the most abundant macrophages in the healthy lung where they play key roles in homeostasis and immune surveillance against airborne…”
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Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury
Published in npj Regenerative medicine (23-05-2017)“…Chronic liver injury can be caused by viral hepatitis, alcohol, obesity, and metabolic disorders resulting in fibrosis, hepatic scarring, and cirrhosis. Novel…”
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Mechanisms responsible for 'scarless' tissue repair in the endometrium
Published 01-01-2019“…The endometrium is the inner lining of the uterine cavity, composed of distinct epithelial and stromal cell compartments with the latter containing…”
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Dissertation -
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Erratum: Author Correction: Injection of embryonic stem cell-derived macrophages ameliorates fibrosis in a murine model of liver injury
Published in npj Regenerative medicine (2017)“…[This corrects the article DOI: 10.1038/s41536-017-0017-0.]…”
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Journal Article -
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Author Correction: Injection of embryonic stem cell-derived macrophages ameliorates fibrosis in a murine model of liver injury
Published in npj Regenerative medicine (13-11-2017)“…The following ethical statement was added to the end of the Methods section in the HTML and PDF versions of this Article: The animal experiments were approved…”
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