Search Results - "Kirkpatrick, Angelia C."
-
1
Cerebral microhemorrhages: mechanisms, consequences, and prevention
Published in American journal of physiology. Heart and circulatory physiology (01-06-2017)“…The increasing prevalence of multifocal cerebral microhemorrhages (CMHs, also known as "cerebral microbleeds") is a significant, newly recognized problem in…”
Get more information
Journal Article -
2
Increased platelet procoagulant potential predicts recurrent stroke and TIA after lacunar infarction
Published in Journal of thrombosis and haemostasis (01-03-2020)“…Background Mean levels of coated‐platelets, a subset of highly procoagulant platelets, are decreased in patients with lacunar as compared to those with…”
Get full text
Journal Article -
3
Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study
Published in PloS one (03-08-2023)“…Mild cognitive impairment (MCI) is a prodromal stage to dementia, affecting up to 20% of the aging population worldwide. Patients with MCI have an annual…”
Get full text
Journal Article -
4
Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease
Published in Frontiers in aging neuroscience (18-11-2022)“…Advanced methods of gait research, including approaches to quantify variability, and orderliness/regularity/predictability, are increasingly used to identify…”
Get full text
Journal Article -
5
Clopidogrel use and smoking cessation result in lower coated-platelet levels after stroke
Published in Platelets (Edinburgh) (17-02-2020)“…Coated-platelets are a subset of highly procoagulant platelets elevated in patients with non-lacunar ischemic stroke and associated with stroke recurrence…”
Get full text
Journal Article -
6
The aging venous system: from varicosities to vascular cognitive impairment
Published in GeroScience (01-12-2021)“…Aging-induced pathological alterations of the circulatory system play a critical role in morbidity and mortality of older adults. While the importance of…”
Get full text
Journal Article -
7
Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age‐Related Cognitive Dysfunction
Published in Advanced science (01-03-2024)“…Impaired cerebrovascular function contributes to the genesis of age‐related cognitive decline. In this study, the hypothesis is tested that impairments in…”
Get full text
Journal Article -
8
Cognitive Impairment Is Associated with Medication Nonadherence in Asymptomatic Carotid Stenosis
Published in The American journal of medicine (01-12-2014)“…Abstract Objective Adherence to medical management of vascular risk is vital for stroke prevention in patients with asymptomatic carotid stenosis. Because…”
Get full text
Journal Article -
9
Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults
Published in GeroScience (01-12-2018)“…Multifocal cerebral microhemorrhages (CMHs, also known as “cerebral microbleeds”), which are associated with rupture of small intracerebral vessels, have been…”
Get full text
Journal Article -
10
Cerebral small vessel disease pathology in COVID-19 patients: A systematic review
Published in Ageing research reviews (01-07-2023)“…Cerebral small vessel disease (CSVD) is the leading cause of vascular cognitive impairment and is associated with COVID-19. However, contributing factors that…”
Get full text
Journal Article -
11
Coated-platelets predict stroke at 30 days following TIA
Published in Neurology (11-07-2017)“…OBJECTIVE:To examine the potential for coated-platelets, a subset of highly procoagulant platelets observed on dual agonist stimulation with collagen and…”
Get full text
Journal Article -
12
Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment
Published in Alzheimer's & dementia (01-08-2024)“…INTRODUCTION Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for…”
Get full text
Journal Article -
13
Coated-Platelets Improve Prediction of Stroke and Transient Ischemic Attack in Asymptomatic Internal Carotid Artery Stenosis
Published in Stroke (1970) (01-10-2014)“…BACKGROUND AND PURPOSE—Coated-platelets, a subset of procoagulant platelets observed on dual agonist stimulation with collagen and thrombin, support a robust…”
Get full text
Journal Article -
14
Higher Coated-Platelet Levels in Acute Stroke are Associated with Lower Cognitive Scores at Three Months Post Infarction
Published in Journal of stroke and cerebrovascular diseases (01-09-2019)“…Background: Coated-platelets are a subset of highly procoagulant platelets observed after dual agonist stimulation with collagen and thrombin. Coated-platelet…”
Get full text
Journal Article -
15
-
16
Neurovascular coupling impairment as a mechanism for cognitive deficits in COVID-19
Published in Brain communications (2024)“…Abstract Components that comprise our brain parenchymal and cerebrovascular structures provide a homeostatic environment for proper neuronal function to ensure…”
Get full text
Journal Article -
17
Increased procoagulant platelet levels are predictive of death in COVID-19
Published in GeroScience (01-08-2021)“…Prior research has identified abnormal platelet procoagulant responses in COVID-19. Coated-platelets, a form of procoagulant platelets, support thrombin…”
Get full text
Journal Article -
18
Higher levels of coated-platelets are observed in patients with subarachnoid hemorrhage but lower levels are associated with increased mortality at 30 days
Published in Journal of the neurological sciences (15-11-2013)“…Abstract Background Coated-platelets are procoagulant platelets observed upon dual agonist stimulation with collagen and thrombin. Coated-platelet levels are…”
Get full text
Journal Article -
19
Cognitive Impairment Is Associated with High Coated-Platelet Levels in Individuals with Carotid Atherosclerosis
Published in Journal of the American Geriatrics Society (JAGS) (01-07-2014)Get full text
Journal Article -
20
Elevated coated-platelets in symptomatic large-artery stenosis patients are associated with early stroke recurrence
Published in Platelets (Edinburgh) (01-01-2014)“…Coated-platelets are a subset of platelets with increased procoagulant potential observed upon dual agonist stimulation with collagen and thrombin. These…”
Get full text
Journal Article