Search Results - "Kirkman, Lucy M. D"

FIKK Kinase, a Ser/Thr Kinase Important to Malaria Parasites, Is Inhibited by Tyrosine Kinase Inhibitors by Lin, Benjamin C, Harris, Darcy R, Kirkman, Lucy M. D, Perez, Astrid M, Qian, Yiwen, Schermerhorn, Janse T, Hong, Min Y, Winston, Dennis S, Xu, Lingyin, Brandt, Gabriel S

“…A relatively high-affinity inhibitor of FIKK kinase from the malaria parasite Plasmodium vivax was identified by in vitro assay of recombinant kinase. The FIKK…”
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The anthraquinone emodin inhibits the non-exported FIKK kinase from Plasmodium falciparum by Lin, Benjamin C., Harris, Darcy R., Kirkman, Lucy M.D., Perez, Astrid M., Qian, Yiwen, Schermerhorn, Janse T., Hong, Min Y., Winston, Dennis S., Xu, Lingyin, Lieber, Alexander M., Hamilton, Matthew, Brandt, Gabriel S.

“…[Display omitted] •The Ser/Thr kinase FIKK 8 from P. falciparum remains localized within the parasite.•Exported and non-exported FIKK kinases have distinct…”
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Re‐refinement of Plasmodium falciparum orotidine 5′‐monophosphate decarboxylase provides a clearer picture of an important malarial drug target by Novak, Walter R. P., West, Korbin H. J., Kirkman, Lucy M. D., Brandt, Gabriel S.

“…The development of antimalarial drugs remains a public health priority, and the orotidine 5′‐monophosphate decarboxylase from Plasmodium falciparum (PfOMPDC)…”
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