Search Results - "Kirkham, P A"

Pharmacological and dietary antioxidant therapies for chronic obstructive pulmonary disease by Biswas, S, Hwang, J W, Kirkham, P A, Rahman, I

“…The progression and exacerbations of chronic obstructive pulmonary disease (COPD) are intimately associated with tobacco smoke/biomass fuel-induced oxidative…”
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Chemokines and chemokine receptors blockers as new drugs for the treatment of chronic obstructive pulmonary disease by Caramori, G, Di Stefano, A, Casolari, P, Kirkham, P A, Padovani, A, Chung, K F, Papi, A, Adcock, I M

“…Chronic obstructive pulmonary disease (COPD) is characterised by an abnormal inflammatory response of the lung to noxious particles or gases. The cellular…”
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A possible overwintering mechanism for bluetongue virus in the absence of the insect vector by Takamatsu, H, Mellor, P. S, Mertens, P. P. C, Kirkham, P. A, Burroughs, J. N, Parkhouse, R. M. E

“…Institute for Animal Health, Pirbright Laboratory, Woking, Surrey GU24 0NF, UK Correspondence Peter Mertens peter.mertens{at}bbsrc.ac.uk Bluetongue virus (BTV)…”
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The acute effects of continuous and conditional neuromodulation on the bladder in spinal cord injury by KIRKHAM, A. P. S, SHAH, N. C, KNIGHT, S. L, SHAH, P. J. R, CRAGGS, M. D

“…Laboratory investigation using serial slow-fill cystometrograms. To examine the acute effects of different modes of dorsal penile nerve stimulation on detrusor…”
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Targeted testicular excision biopsy: when and how should we try to avoid radical orchidectomy? by Kirkham, A.P.S, Kumar, P, Minhas, S, Freeman, A.A, Ralph, D.J, Muneer, A, Allen, C

“…Small, incidental testicular lesions are often benign, but in the past have usually been treated by orchidectomy. An alternative is an operative excision…”
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Prostate MRI: Who, when, and how? Report from a UK consensus meeting by Kirkham, A.P.S, Haslam, P, Keanie, J.Y, McCafferty, I, Padhani, A.R, Punwani, S, Richenberg, J, Rottenberg, G, Sohaib, A, Thompson, P, Turnbull, L.W, Kurban, L, Sahdev, A, Clements, R, Carey, B.M, Allen, C

“…The current pathway for men suspected of having prostate cancer [transrectal biopsy, followed in some cases by magnetic resonance imaging (MRI) for staging]…”
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A multi-centre prospective development study evaluating focal therapy using high intensity focused ultrasound for localised prostate cancer: The INDEX study by Dickinson, L, Ahmed, H.U, Kirkham, A.P, Allen, C, Freeman, A, Barber, J, Hindley, R.G, Leslie, T, Ogden, C, Persad, R, Winkler, M.H, Emberton, M

“…Abstract Introduction Focal therapy offers the possibility of cancer control, without the side effect profile of radical therapies. Early single centre…”
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A B lymphocyte surface molecule mediating activation and protection from apoptosis via calcium channels by Santos-Argumedo, L, Teixeira, C, Preece, G, Kirkham, PA, Parkhouse, RM

“…A rat mAb (NIM-R5) was prepared against a 42-kD B cell activation Ag (p42). The expression of p42 is increased upon activation. NIM-R5 induces an increase of…”
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Cigarette smoke triggers macrophage adhesion and activation: role of lipid peroxidation products and scavenger receptor by Kirkham, Paul A, Spooner, Gillian, Ffoulkes-Jones, Claire, Calvez, Ronan

“…Pulmonary emphysema in chronic obstructive pulmonary disease (COPD) is characterized by the destruction of the alveolar walls leading to permanent enlargement…”
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Preparation of monoclonal anti‐porcine CD3 antibodies and preliminary characterization of porcine T lymphocytes by YANG, H., OURA, C. A. L., KIRKHAM, P. A., PARKHOUSE, R. M. E.

“…The CD3–T‐cell receptor complex is the clonotypic surface structure by which T lymphocytes recognize foreign antigens and are subsequently activated. Because…”
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Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products by Kirkham, Paul A, Spooner, Gillian, Rahman, Irfan, Rossi, Adriano G

“…Clearance of apoptotic cells by phagocytosis plays an important role in the resolution of an inflammatory response. Macrophages interacting with extracellular…”
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Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule by Torres, RM, Law, CL, Santos-Argumedo, L, Kirkham, PA, Grabstein, K, Parkhouse, RM, Clark, EA

“…The human B lymphocyte-specific Ag, CD22, is a cell adhesion molecule expressed on the surface during a narrow window of B cell development, coincident with…”
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Neuromodulation through sacral nerve roots 2 to 4 with a Finetech-Brindley sacral posterior and anterior root stimulator by KIRKHAM, A. P. S, KNIGHT, S. L, CRAGGS, M. D, CASEY, A. T. M, SHAH, P. J. R

“…Investigation of five patients receiving an implant, using laboratory cystometry and self-catheterisation at home. To use the established Finetech-Brindley…”
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Porcine CD3ε: its characterization, expression and involvement in activation of porcine T lymphocytes by KIRKHAM, P. A., TAKAMATSU, H., YANG, H., PARKHOUSE, R. M. E.

“…The cloning, characterization and expression of porcine CD3ε and establishment of its role in T‐cell activation using an anti‐porcine CD3ε monoclonal antibody,…”
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Murine B-cell activation via CD38 and protein tyrosine phosphorylation by Kirkham, P A, Santos-Argumedo, L, Harnett, M M, Parkhouse, R M

“…CD38 has been implicated in the regulation of both proliferation and rescue from apoptosis of B cells. The signalling events associated with CD38-mediated…”
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A possible overwintering mechanism for bluetongue virus in the absence of the insect vector FN1 by Takamatsu, H., Mellor, P. S., Mertens, P. P. C., Kirkham, P. A., Burroughs, J. N., Parkhouse, R. M. E.

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Cadaveric dissection for the rectal surgeon by Kirkham, A P, Mundy, A R, Heald, R J, Scholefield, J H

“…The benefits of total mesorectal excision are due to the complete excision of the mesorectum with preservation of the pelvic autonomic nerve plexuses, the…”
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C74 MODELS AND METHODS IN LUNG BIOLOGY: Modeling Environmental Mediated Extracellular Matrix Chemical Modifications In The Lung: Implications In Profibrotic And Inflammatory Responses by Lerner, C A, Lei, W, Sundar, I, Kirkham, P A, Rahman, I

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The detection of an early advanced glycation product which co-elutes with the Amadori product on aminophenylboronate affinity chromatography by Kirkham, P A, Morris, B A, Gould, B J

“…The production of an antiserum recognizing an early advanced glycation product of glycated human serum albumin (HSA) is reported. The antiserum was produced…”
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A gamma delta T cell specific surface receptor (WC1) signaling G0/G1 cell cycle arrest by Takamatsu, H H, Kirkham, P A, Parkhouse, R M

“…Three monoclonal antibodies (mAb; SC-6, SC-12, and SC-29) reactive with the gammadelta T cell-restricted antigen WC1 were obtained immunizing mice with an…”
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