Search Results - "Kirkham, D. M."

Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling by Young, P. W., Cawthorne, M. A., Coyle, P. J., Holder, J. C., Holman, G. D., Kozka, I. J., Kirkham, D. M., Lister, C. A., Smith, S. A.

“…Repeat treatment of obese mice with BRL 49653, a new potent insulin sensitizer, enhances insulin action in white adipocytes. Association with increased insulin…”
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The role of vascular laboratory in the management of Eagle syndrome by Esiobu, Prince C., MD, Yoo, Mi Jin, MD, Kirkham, Erin M., MD, Zierler, R. Eugene, MD, Starnes, Benjamin W., MD, Sweet, Matthew P., MD

“…Abstract Eagle syndrome is caused by an elongated styloid process or calcified stylohyoid ligament. The stylocarotid variant with neurologic symptoms is rare…”
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The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344 by Oriowo, M A, Chapman, H, Kirkham, D M, Sennitt, M V, Ruffolo, Jr, R R, Cawthorne, M A

“…The stimulation by BRL 37344 of lipolysis in rat adipose tissues, and of relaxation of the rat distal colon, is mediated by the beta-3 adrenoceptor. The…”
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Evaluation of inhibitory guanine nucleotide regulatory protein Gi function in hepatocyte and liver membranes from obese Zucker (fa/fa) rats and their lean (FA/?) littermates by YOUNG, P, KIRKHAM, D. M, MURPHY, G. J, CAWTHORNE, M. A

“…Previous studies have shown that hepatocyte and liver membranes from insulin resistant animals exhibit an impairment of inhibitory guanine nucleotide binding…”
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Demonstration of inhibitory guanine nucleotide regulatory protein (Gi) function in liver and hepatocyte membranes from streptozotocin-treated rats by KIRKHAM, D. M, MURPHY, G. J, YOUNG, P

“…By using a defined plasma-membrane preparation, functional inhibition of adenylate cyclase activity by the inhibitory G-protein (Gi) was observed in liver and…”
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Repeat treatment of obese mice with BRL 49653, a new and potent insulin sensitizer, enhances insulin action in white adipocytes : association with increased insulin binding and cell-surface GLUT4 as measured by photoaffinity labeling by YOUNG, P. W, CAWTHORNE, M. A, COYLE, P. J, HOLDER, J. C, HOLMAN, G. D, KOZKA, I. J, KIRKHAM, D. M, LISTER, C. A, SMITH, S. A

“…(+/-)-5-([4-[2-Methyl-2(pyridylamino)ethoxy]phenyl]methyl) 2,4-thiazolidinedione (BRL 49653) is a new potent antidiabetic agent that improves insulin…”
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Mercuric chloride modulates [3H]AMPA binding to Xenopus brain membranes by Henley, J M, Kirkham, D M

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Characterization of adenylyl cyclase in goldfish brain by Kirkham, D M, Henley, J M

“…The rate of production of cAMP by the adenylyl cyclase enzyme from goldfish brain was linear with time and with protein concentration. In agreement with…”
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Characteristics of the goldfish brain adenylyl cyclase system by Kirkham, D M, Henley, J M

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Correlation of beta 3-adrenoceptor-induced activation of cyclic AMP-dependent protein kinase with activation of lipolysis in rat white adipocytes by Murphy, G J, Kirkham, D M, Cawthorne, M A, Young, P

“…The lipolytic action of the beta 3-adrenoceptor-selective agonist 4-[2-[(2-hydroxy-2-(3-chlorophenyl)ethyl)-amino]propyl]-phenoxyacetic acid (BRL 37344) was…”
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Solubilization and purification of a functional ionotropic excitatory amino acid receptor by Henley, J M, Kirkham, D M

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Management of thoracolumbar spine fractures by Wood, Kirkham B., MD, Li, Weishi, MD, Lebl, Darren S., MD, Ploumis, Avraam, MD

“…Abstract Background context Traumatic fractures of the spine are most common at the thoracolumbar junction and can be a source of great disability. Purpose To…”
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Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial by McInnes, Iain B, Prof, Mease, Philip J, Prof, Kirkham, Bruce, MD, Kavanaugh, Arthur, Prof, Ritchlin, Christopher T, Prof, Rahman, Proton, Prof, van der Heijde, Désirée, Prof, Landewé, Robert, Prof, Conaghan, Philip G, Prof, Gottlieb, Alice B, Prof, Richards, Hanno, MD, Pricop, Luminita, MD, Ligozio, Gregory, MSc, Patekar, Manmath, MD, Mpofu, Shephard, MD

“…Summary Background Interleukin 17A is a proinflammatory cytokine that is implicated in the pathogenesis of psoriatic arthritis. We assessed the efficacy and…”
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Assessment of Gi function in an animal model of non-insulin dependent diabetes by Murphy, G J, Kirkham, D M, Cawthorne, M A, Young, P

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Independent predictors of failure of nonoperative management of spinal epidural abscesses by Kim, Sang Do, MD, MS, Melikian, Rojeh, MD, Ju, Kevin L., MD, Zurakowski, David, PhD, Wood, Kirkham B., MD, Bono, Christopher M., MD, Harris, Mitchel B., MD

“…Abstract Background context The notion that all patients with spinal epidural abscess (SEA) require surgical decompression has been recently challenged by…”
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Allogeneic blood transfusions and postoperative infections after lumbar spine surgery by Janssen, Stein J., MD, Braun, Yvonne, MD, Wood, Kirkham B., MD, Cha, Thomas D., MD, MBA, Schwab, Joseph H., MD, MS

“…Abstract Background context Allogeneic blood transfusions have an immunomodulating effect, and the previous studies in other fields of medicine demonstrated an…”
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Optimizing Prescribing of Antipsychotics in Long-Term Care (Opal) by Kirkham, Julia, MD, MSc, Seitz, Dallas, MD, PhD

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Dimensional changes of the neuroforamina in subaxial cervical spine during in vivo dynamic flexion-extension by Mao, Haiqing, MD, Driscoll, Sean J., MEng, Li, Jing-Sheng, PT, MS, Li, Guoan, PhD, Wood, Kirkham B., MD, Cha, Thomas D., MD, MBA

“…Abstract Background Context Neuroforaminal stenosis is one of the key factors causing clinical symptoms in patients with cervical radiculopathy. Previous…”
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Prevalence of Psychotropic Medication Use Among Older Adults with Dementia: Meta-Analysis by Seitz, Dallas, MD, PhD, Sherman, Chelsea, BSc, Kirkham, Julia, MD

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In vivo dynamic changes of dimensions in the lumbar intervertebral foramen by Zhong, Weiye, MD, Driscoll, Sean J., MEng, Tsai, Tsung-Yuan, PhD, Wang, Shaobai, PhD, Mao, Haiqing, MD, Cha, Thomas D., MD, Wood, Kirkham B., MD, Li, Guoan, PhD

“…Abstract Background context Previous studies have reported position-dependent changes of the lumbar intervertebral foramen (LIVF) dimensions at different…”
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