Search Results - "Kirk, Samuel R."
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On the structural denaturation of biological analytes in trapped ion mobility spectrometry - mass spectrometry
Published in Analyst (London) (07-06-2016)“…Key to native ion mobility/mass spectrometry is to prevent the structural denaturation of biological molecules in the gas phase. Here, we systematically assess…”
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Tandem Trapped Ion Mobility Spectrometry/Mass Spectrometry (tTIMS/MS) Reveals Sequence-Specific Determinants of Top-Down Protein Fragment Ion Cross Sections
Published in Analytical chemistry (Washington) (14-06-2022)“…Top-down proteomics provides a straightforward approach to the level of proteoforms but remains technologically challenging. Using ion mobility…”
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On the Preservation of Non-covalent Peptide Assemblies in a Tandem-Trapped Ion Mobility Spectrometer-Mass Spectrometer (TIMS-TIMS-MS)
Published in Journal of the American Society for Mass Spectrometry (01-07-2019)“…Ion mobility spectrometry-mass spectrometry (IMS-MS) has demonstrated the ability to characterize structures of weakly-bound peptide assemblies. However, these…”
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Hybrid-virtual simulations for Canadian medical students during the COVID-19 pandemic
Published in Canadian medical education journal (01-09-2021)“…Implication Statement: Given the efficacy of simulations as a medical education tool, the inability to provide them during the COVID-19 pandemic may be…”
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