Search Results - "Kirk, Jonathon"

A new paradigm of hearing loss and preservation with cochlear implants: Learnings from fundamental studies and clinical research by Kirk, Jonathon R., Smyth, Daniel, Dueck, Wolfram F.

“…•Major outcomes and learnings of the Cochlear-sponsored collaborative Residual Hearing Research Program are described.•Novel tools and systematic approach…”
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A mouse model of cochlear implantation with chronic electric stimulation by Claussen, Alexander D, Vielman Quevedo, René, Mostaert, Brian, Kirk, Jonathon R, Dueck, Wolfram F, Hansen, Marlan R

“…Cochlear implants provide an effective treatment option for those with severe hearing loss, including those with preserved low frequency hearing. However,…”
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Therapeutics for hearing preservation and improvement of patient outcomes in cochlear implantation—Progress and possibilities by Gay, Robert D., Enke, Ya Lang, Kirk, Jonathon R., Goldman, Denise R.

“…The emergence of therapeutics targeted at hearing loss holds great promise in the development of novel treatments for this heterogenous condition. Whilst such…”
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Chronic Electro-Acoustic Stimulation May Interfere With Electric Threshold Recovery After Cochlear Implantation in the Aged Guinea Pig by Reiss, Lina A J, Lawrence, Melissa B, Omelchenko, Irina A, He, Wenxuan, Kirk, Jonathon R

“…Electro-acoustic stimulation (EAS) combines electric stimulation via a cochlear implant (CI) with residual low-frequency acoustic hearing, with benefits for…”
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Chronic cochlear implantation with and without electric stimulation in a mouse model induces robust cochlear influx of CX3CR1+/GFP macrophages by Claussen, Alexander D., Quevedo, René Vielman, Kirk, Jonathon R., Higgins, Timon, Mostaert, Brian, Rahman, Muhammad Taifur, Oleson, Jacob, Hernandez, Reyna, Hirose, Keiko, Hansen, Marlan R.

“…•Cochlear implantation initiates a cochlear innate immune response with accumulation of macrophages•The chronic presence of an indwelling cochlear implant is…”
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Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation by Rahman, Muhammad Taifur, Mostaert, Brian J, Hunger, Bryce, Saha, Utsow, Claussen, Alexander D, Razu, Ibrahim, Nasrin, Farjana, Khan, Nashwaan Ali, Eckard, Peter, Coleman, Sarah, Oleson, Jacob, Kirk, Jonathon R, Hirose, Keiko, Hansen, Marlan R

“…Cochlear implants (CIs) restore hearing to deafened patients. The foreign body response (FBR) following cochlear implantation (post-CI) comprises an…”
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Perilymph pharmacokinetics of marker applied through a cochlear implant in guinea pigs by Salt, Alec, Hartsock, Jared, Gill, Ruth, Smyth, Daniel, Kirk, Jonathon, Verhoeven, Kristien

“…Patients undergoing cochlear implantation could benefit from a simultaneous application of drugs into the ear, helping preserve residual low-frequency hearing…”
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Effect of Return Electrode Placement at Apical Cochleostomy on Current Flow With a Cochlear Implant by Landsberger, David M, Long, Christopher J, Kirk, Jonathon R, Stupak, Natalia, Roland, Jr, J Thomas

“…A method for stimulating the cochlear apex using perimodiolar electrode arrays is described. This method involves implanting an electrode (ECE1) into the…”
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Acoustic Hearing After Murine Cochlear Implantation: Effects of Trauma and Implant Type by Kopelovich, Jonathan C., Robinson, Barbara K., Soken, Hakan, Verhoeven, Kristien J., Kirk, Jonathon R., Goodman, Shawn S., Hansen, Marlan R.

“…Objectives: To model the contribution of implant material and insertion trauma on loss of acoustic hearing after cochlear implantation in an appropriate animal…”
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Radiation therapy in cochlear implant recipients by Gossman, Michael S, Treaba, Claudiu G, Kirk, Jonathon R

“…Processes of scattering and attenuation were investigated to determine the consequence on dose distributions by having a cochlear implant in the field of…”
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Cochlear implant imaging in the mouse and guinea pig using light-sheet microscopy by Santi, Peter A., Johnson, Shane, Wüster, Julian, Griesbach, Matthew, Claussen, Alexander, Kirk, Jonathon

“…•Light-sheet microscopy was used to examine mouse and guinea pig cochleas with and without cochlear implants.•Due to absorption and refection of light from the…”
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Evaluation of a Slim Modiolar Electrode Array: A Temporal Bone Study by Asfour, Leena, Risi, Frank, Treaba, Claudiu, Kirk, Jonathon, Roland Thomas, Jr, J

“…Evaluation of the Slim Modiolar (SM) electrode in temporal bones (TB) will elucidate the electrode's insertion outcomes. The SM electrode was designed for…”
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Animal Models of Hearing Loss after Cochlear Implantation and Electrical Stimulation by Reiss, Lina A.J., Kirk, Jonathon, Claussen, Alexander D., Fallon, James B.

“…•Animal models of cochlear implants are an essential tool to investigate clinical problems including post-implantation hearing loss.•Animal models may also…”
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Cochlear implant material effects on inflammatory cell function and foreign body response by Jensen, Megan J., Claussen, Alexander D., Higgins, Timon, Vielman-Quevedo, Rene, Mostaert, Brian, Xu, Linjing, Kirk, Jonathon, Hansen, Marlan R.

“…•Cochlear implant electrodes are comprised of platinum contacts in a PDMS casing.•Components of cochlear implant biomaterials influence the cellular…”
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