Search Results - "Kirk, B. E"

The Squalestatins:  Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in Vivo Evaluation of C3-Modified Analogues by Procopiou, Panayiotis A, Cox, Brian, Kirk, Barrie E, Lester, Michael G, McCarthy, Alun D, Sareen, Meenu, Sharratt, Peter J, Snowden, Michael A, Spooner, Stephen J, Watson, Nigel S, Widdowson, Julia

“…Squalestatin analogues modified at C3 were prepared and evaluated for their ability to inhibit rat liver microsomal squalene synthase in vitro. While the…”
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The Squalestatins: Novel Inhibitors of Squalene Synthase. Enzyme Inhibitory Activities and in vivo Evaluation of C1-Modified Analogs by Procopiou, Panayiotis A, Bailey, Esme J, Bamford, Mark J, Craven, Andy P, Dymock, Brian W, Houston, John G, Hutson, Julie L, Kirk, Barrie E, McCarthy, Alun D

“…Squalestatin analogues modified in the C1 side chain were prepared and evaluated for their ability to inhibit rat liver microsomal and Candida squalene…”
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The Squalestatins: Synthesis and Biological Activity of Some C3-Modified Analogs; Replacement of a Carboxylic Acid or Methyl Ester with an Isoelectronic Heterocyclic Functionality by Bamford, Mark J, Chan, Chuen, Craven, Andrew P, Dymock, Brian W, Green, Darren, Henson, Richard A, Kirk, Barrie E, Lester, Michael G, Procopiou, Panayiotis A

“…A series of squalestatins modified at the C3-position with a heterocyclic functionality was prepared and evaluated in vitro as inhibitors of squalene synthase…”
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Mycoplasma-induced hydrocephalus in rats and hamsters by Kohn, D F, Kirk, B E, Chou, S M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis of Baby Hamster Kidney Cells Persistently Infected with Lymphocytic Choriomeningitis Virus by Stanwick, T. L, Kirk, B. E

“…Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30303 B. E. Kirk Department of Microbiology, West Virginia University Medical…”
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Fluorocarbocyclic nucleosides : synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxy guanosines by BORTHWICK, A. D, KIRK, B. E, BIGGADIKE, K, EXALL, A. M, BUTT, S, ROBERTS, S. M, KNIGHT, D. J, COATES, J. A. V, RYAN, D. M

“…A series of four isomeric 2'- and 6'-fluorocarbocyclic guanosine analogues have been prepared and evaluated as potential anti-herpes agents. The racemic 2'…”
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An Antiviral Substance in the Tissues of Mice Acutely Infected with Lymphocytic Choriomeningitis Virus by Veltri, R. W, Kirk, B. E

“…Department of Microbiology, West Virginia University Medical Center, Morgantown, West Virginia 26506 Injection of mice with mouse brain suspensions of…”
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Neutralizing Antibody Response of Guinea Pigs to Lymphocytic Choriomeningitis Virus by Webster, J M, Kirk, B E

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Immunofluorescent cell-counting assay for lymphocytic choriomeningitis virus by Webster, J M, Kirk, B E

“…A quantitative assay for lymphocytic choriomeningitis virus was developed and standardized. The assay is based on direct immunofluorescent staining of infected…”
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Effect of Actinomycin D on the Yield of Lymphocytic Choriomeningitis Virus in Baby Hamster Kidney Cells by Stanwick, T L, Kirk, B E

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Effect of serum on the yield of lymphocytic choriomeningitis virus in baby hamster kidney cells by Stanwick, T L, Kirk, B E

“…The yields of the Armstrong and WE strains of lymphocytic choriomeningitis virus in baby hamster kidney (BHK) cells cultivated in either bovine, calf, fetal…”
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Complement-fixing antigen from BHK-21 cell cultures infected with lymphocytic choriomeningitis virus by Brown, W J, Kirk, B E

“…Infection of BHK-21 cells with lymphocytic choriomeningitis (LCM) virus resulted in the production of significant titers of complement-fixing (CF) antigen. The…”
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A One-Dose Potency Test for Poliomyelitis Vaccine by Van Frank, R. M, Havens, M. L, MacFarlane, J. O, Boand, A. V, Kirk, B. E, Hosley, R. J

“…Studies leading to the development and use of a one-dose potency test for poliomyelitis vaccine are described. The test is based on the measurement of…”
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Pathogenicity of Mycoplasma pulmonis in laboratory rats by Kohn, D F, Kirk, B E

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Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma by Bernal, Giovanna M., PhD, LaRiviere, Michael J., BA, Mansour, Nassir, MD, Pytel, Peter, MD, Cahill, Kirk E., BS, Voce, David J., BS, Kang, Shijun, MD, Spretz, Ruben, PhD, Welp, Ulrich, PhD, Noriega, Sandra E., PhD, Nuñez, Luis, PhD, Larsen, Gustavo, PhD, Weichselbaum, Ralph R., MD, Yamini, Bakhtiar, MD

“…Abstract A major obstacle to the management of malignant glioma is the inability to effectively deliver therapeutic agent to the tumor. In this study, we…”
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Relation of Fish Oil Supplementation to Markers of Atherothrombotic Risk in Patients With Cardiovascular Disease Not Receiving Lipid-Lowering Therapy by Franzese, Christopher J., BS, Bliden, Kevin P., MBA, Gesheff, Martin G., BS, Pandya, Shachi, MD, Guyer, Kirk E., BS, Singla, Anand, MD, Tantry, Udaya S., PhD, Toth, Peter P., MD, PhD, Gurbel, Paul A., MD

“…Fish oil supplementation (FOS) is known to have cardiovascular benefits. However, the effects of FOS on thrombosis are incompletely understood. We sought to…”
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Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-iodouracil by Borthwick, Alan D, Evans, Derek N, Kirk, Barrie E, Biggadike, Keith, Exall, Anne M, Youds, Peter, Roberts, Stanley M, Knight, David J, Coates, Jonathan A. V

“…The racemic carbocyclic 2'-fluoroarabinosyl pyrimidine nucleosides 8, 9 (C-FIAU), 12, and 13 (C-FMAU) and the 2'-fluororibosyl pyrimidine nucleosides 17, 20,…”
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Further Studies on the Light Sense in Early Glaucoma by Derby, G S, Waite, J H, Kirk, E B

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Mycoplasma species found in naturally occurring adenotonsillitis by Sprinkle, P M, Kirk, B E, Mathias, P B

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Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors by Chan, C, Bailey, E J, Hartley, C D, Hayman, D F, Hutson, J L, Inglis, G G, Jones, P S, Keeling, S E, Kirk, B E, Lamont, R B

“…3,5-Dihydroxy-7-(N-imidazolyl)heptanoates 4 and the corresponding heptenoates 5 were synthesized as novel classes of potent HMG-CoA reductase (HMGR) inhibitors…”
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