Search Results - "Kirinashizawa, Mika"

Generation and characterization of monoclonal antibodies against mature hepcidin and its application to neutralization and quantitative alteration assay by Sakamoto, Shinji, Kirinashizawa, Mika, Mohara, Yumi, Watanabe, Yoshihiro

“…Hepcidin regulates the quantity of ferroportin (FPN) on cellular membrane. In our cell assay expressing ferroportin labeled with green fluorescence, FPN was…”
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First-in-human autologous implantation of genetically modified adipocytes expressing LCAT for the treatment of familial LCAT deficiency by Aso, Masayuki, Yamamoto, Tokuo T., Kuroda, Masayuki, Wada, Jun, Kubota, Yoshitaka, Ishikawa, Ko, Maezawa, Yoshiro, Teramoto, Naoya, Tawada, Ayako, Asada, Sakiyo, Aoyagi, Yasuyuki, Kirinashizawa, Mika, Onitake, Akinobu, Matsuura, Yuta, Yasunaga, Kunio, Konno, Shun-ichi, Nishino, Katsuaki, Yamamoto, Misato, Miyoshi, Junko, Kobayashi, Norihiko, Tanio, Masami, Ikeuchi, Takayuki, Igari, Hidetoshi, Mitsukawa, Nobuyuki, Hanaoka, Hideki, Yokote, Koutaro, Saito, Yasushi

“…Familial lecithin: cholesterol acyltransferase (LCAT) deficiency (FLD) is a severe inherited disease without effective treatment. Patients with FLD develop…”
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Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation by Ishii, Takamasa, Miyazawa, Masaki, Onodera, Akira, Yasuda, Kayo, Kawabe, Noboru, Kirinashizawa, Mika, Yoshimura, Shinichi, Maruyama, Naoki, Hartman, Philip S, Ishii, Naoaki

“…We have previously demonstrated that excessive mitochondrial reactive oxygen species caused by mutations in the SDHC subunit of Complex II resulted in…”
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Novel pathogenic variant in the LCAT gene in a compound heterozygous patient with fish-eye disease and a mild phenotype by Miyata, Masaaki, Kuroda, Masayuki, Miyoshi, Junko, Kirinashizawa, Mika, Nagasawa, Rora, Yamamoto, Misato, Akasaki, Yuichi, Utatsu, Kensuke, Maezawa, Yoshiro, Yokote, Koutaro, Ohishi, Mitsuru

“…•LCAT activity measurement is the ideal way to identify conditions caused by LCAT gene variants among low HDL-cholesterolemia.•LCAT activity assay is not…”
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A novel homozygous frameshift mutation in the APOA1 gene associated with marked high-density lipoprotein deficiency by Takeda, Tadashi, Ide, Tsubasa, Okuda, Daishi, Kuroda, Masayuki, Asada, Sakiyo, Kirinashizawa, Mika, Yamamoto, Misato, Miyoshi, Junko, Yokote, Koutaro, Mizutani, Naohiro

“…•A patient with low HDL-cholesterol and corneal opacity was identified.•The patient showed no apparent atherosclerosis or CAD.•LCAT activity is relatively…”
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Cell growth of the mouse SDHC mutant cells was suppressed by apoptosis throughout mitochondrial pathway by Miyazawa, Masaki, Ishii, Takamasa, Kirinashizawa, Mika, Yasuda, Kayo, Hino, Okio, Hartman, Philip S, Ishii, Naoaki

“…SDHC E69 cells, which overproduce superoxide anions in their mitochondria, were previously established that had a mutation in the SDHC gene of complex II of…”
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