Probiotics against Campylobacter Pathogens
Background: The subject matter of this study was to investigate, for the first time, the immediate-preventive effect of probiotics, composed of bacillus species, in a murine model of Campylobacter infection. Methods: An established model of Campylobacter infection in mice with a defined LD50 was uti...
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| Published in: | Journal of travel medicine Vol. 4; no. 4; pp. 167 - 170 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
01-12-1997
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| Online Access: | Get full text |
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| Summary: | Background: The subject matter of this study was to investigate, for the first time, the immediate-preventive effect of probiotics, composed of bacillus species, in a murine model of Campylobacter infection. Methods: An established model of Campylobacter infection in mice with a defined LD50 was utilized to assess the protective effect of probiotics. Results: The results obtained demonstrate that the level of animal protection, after a single administration of the new probiotics biosporin and subalin, reached 90-100% at LD50 and 80% at LD100. Conclusions: Such efficacy of probiotics is considered to be due to their high antagonistic activity against those pathogens registered in vitro. Antagonistic activity of other tested probiotics (bactisubtil and cereobiogen) to different cultures of Campylobacter was not manifested. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1195-1982 1708-8305 |
| DOI: | 10.1111/j.1708-8305.1997.tb00813.x |