Search Results - "Kirby, Monica B."

An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries by Petersen, Brian M., Kirby, Monica B., Chrispens, Karson M., Irvin, Olivia M., Strawn, Isabell K., Haas, Cyrus M., Walker, Alexis M., Baumer, Zachary T., Ulmer, Sophia A., Ayala, Edgardo, Rhodes, Emily R., Guthmiller, Jenna J., Steiner, Paul J., Whitehead, Timothy A.

“…Antibodies are engineerable quantities in medicine. Learning antibody molecular recognition would enable the in silico design of high affinity binders against…”
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Facile Assembly of Combinatorial Mutagenesis Libraries Using Nicking Mutagenesis by Kirby, Monica B, Whitehead, Timothy A

“…Combinatorial mutagenesis is a method where multiple user-defined mutations are encoded at defined positions in a sequence. Combinatorial mutagenic libraries…”
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One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening by Francino-Urdaniz, Irene M., Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Leonard, Alison C., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.

“…The potential emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) escape mutants is a threat to the efficacy of existing…”
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Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries by Kirby, Monica B, Medina-Cucurella, Angélica V, Baumer, Zachary T, Whitehead, Timothy A

“…Abstract Generating combinatorial libraries of specific sets of mutations are essential for addressing protein engineering questions involving contingency in…”
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User-defined single pot mutagenesis using unamplified oligo pools by Medina-Cucurella, Angélica V, Steiner, Paul J, Faber, Matthew S, Beltrán, Jesús, Borelli, Alexandra N, Kirby, Monica B, Cutler, Sean R, Whitehead, Timothy A

“…Abstract User-defined mutagenic libraries are fundamental for applied protein engineering workflows. Here we show that unamplified oligo pools can be used to…”
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