Search Results - "Kirby, Duncan"

  • Showing 1 - 10 results of 10
Refine Results
  1. 1

    Determinants of Ligand Specificity and Functional Plasticity in Type I Interferon Signaling by Kirby, Duncan, Parmar, Baljyot, Fathi, Sepehr, Marwah, Sagar, Nayak, Chitra R, Cherepanov, Vera, MacParland, Sonya, Feld, Jordan J, Altan-Bonnet, Grégoire, Zilman, Anton

    Published in Frontiers in immunology (07-10-2021)
    “…The Type I Interferon family of cytokines all act through the same cell surface receptor and induce phosphorylation of the same subset of response regulators…”
    Get full text
    Journal Article
  2. 2
  3. 3

    Proofreading does not result in more reliable ligand discrimination in receptor signaling due to its inherent stochasticity by Kirby, Duncan, Zilman, Anton

    “…Kinetic proofreading (KPR) has been used as a paradigmatic explanation for the high specificity of ligand discrimination by cellular receptors. KPR enhances…”
    Get full text
    Journal Article
  4. 4
  5. 5

    Mesoscopic Models of Cellular Signaling Reveal Strategies for Specificity in Crosstalk Signal Pathways by Kirby, Duncan

    Published 01-01-2023
    “…Successful cellular signal processing strategies must be robust to stochastic fluctuations and yet sensitive to small differences between molecular signals,…”
    Get full text
    Dissertation
  6. 6

    Pleiotropy enables specific and accurate signaling in the presence of ligand cross talk by Kirby, Duncan, Rothschild, Jeremy, Smart, Matthew, Zilman, Anton

    Published 02-04-2021
    “…Phys. Rev. E 103, 042401 (2021) Living cells sense their environment through the binding of extra-cellular molecular ligands to cell surface receptors…”
    Get full text
    Journal Article
  7. 7
  8. 8
  9. 9
  10. 10