Search Results - "Kips, J. C."

Airway eosinophilia is not a requirement for allergen-induced airway hyperresponsiveness by TOURNOY, K. G, KIPS, J. C, SCHOU, C, PAUWELS, R. A

“…Background House dust mites (HDMs) are the major source of perennial allergens causing human allergic asthma. Animal models mimicking as closely as possible…”
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Endogenous interleukin-10 suppresses allergen-induced airway inflammation and nonspecific airway responsiveness by TOURNOY, K. G, KIPS, J. C, PAUWELS, R. A

“…Background The airway inflammation observed in asthma is orchestrated by activated Th‐2 lymphocytes relevant for the induction of altered airway…”
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Murine models of asthma by Kips, J.C, Anderson, G.P, Fredberg, J.J, Herz, U, Inman, M.D, Jordana, M, Kemeny, D.M, Lotvall, J, Pauwels, R.A, Plopper, C.G, Schmidt, D, Sterk, P.J, Van Oosterhout, A.J.M, Vargaftig, B.B, Chung, K.F

“…In vivo animal models can offer valuable information on several aspects of asthma pathogenesis and treatment. The mouse is increasingly used in these models,…”
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Attenuation of allergic airway inflammation in IL-4 deficient mice by Brusselle, G G, Kips, J C, Tavernier, J H, van der Heyden, J G, Cuvelier, C A, Pauwels, R A, Bluethmann, H

“…To investigate the role of IL-4 in vivo in allergic asthma, we developed a murine model of allergen-induced airway inflammation. Repeated daily exposures of…”
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The cellular composition of induced sputum in chronic obstructive pulmonary disease by Peleman, RA, Rytila, PH, Kips, JC, Joos, GF, Pauwels, RA

“…Asthma and chronic obstructive pulmonary disease are characterized by airway inflammation, which can be assessed by bronchoscopic techniques as well as by the…”
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A Long-term Study of the Antiinflammatory Effect of Low-dose Budesonide Plus Formoterol versus High-dose Budesonide in Asthma by KIPS, JOHAN C, O'CONNOR, BRIAN J, INMAN, MARK D, SVENSSON, KLAS, PAUWELS, ROMAIN A, O'BYRNE, PAUL M

“…Adding inhaled long-acting beta(2)-agonists to a low dose of inhaled corticosteroids (ICS), results in better clinical asthma control than increasing the dose…”
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Airway wall remodelling: does it occur and what does it mean? by KIPS, J. C, PAUWELS, R. A

“…The concept of asthma as a chronic inflammatory disorder of the airways has gained widespread acceptance over the past decade: at the same time, increasing…”
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New anti-asthma therapies: suppression of the effect of interleukin (IL)-4 and IL-5 by Kips, J.C, Tournoy, K.G, Pauwels, R.A

“…Asthma is currently defined as a chronic inflammatory disorder of the airways. The central role of allergen-specific Th2 cells in the regulation of this…”
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Dose-related effect of inhaled fluticasone on allergen-induced airway changes in rats by Vanacker, N.J, Palmans, E, Pauwels, R.A, Kips, J.C

“…To examine whether fluticasone propionate (FP) dose-dependently inhibits inflammatory as well as structural changes, Brown Norway rats were sensitised to…”
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Repeated allergen exposure changes collagen composition in airways of sensitised Brown Norway rats by Palmans, E, Pauwels, R.A, Kips, J.C

“…Increased or altered collagen deposition in the airway wall is one of the characteristics of airway remodelling in asthma. The mechanisms underlying this…”
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Fluticasone inhibits the progression of allergen-induced structural airway changes by Vanacker, N. J., Palmans, E., Pauwels, R. A., Kips, J. C.

“…Summary Background Inhaled corticosteroids are widely used as first‐line therapy in patients with asthma. The concept of early introduction is more and more…”
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Is Th1 the solution for Th2 in asthma? by Tournoy, K. G., Kips, J. C., Pauwels, R. A.

“…The increasing awareness that inflamed airways represent the key factor in the pathogenesis of asthma has important therapeutic implications. The most…”
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Clinical applications of assessment of airway inflammation using induced sputum by Pavord, I D, Sterk, P J, Hargreave, F E, Kips, J C, Inman, M D, Louis, R, Pizzichini, M M M, Bel, E H, Pin, I, Grootendorst, D C, Parameswaran, K, Djukanović, R

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Asthma control: where do we fail? by Kips, J C, Pauwels, R A

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Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma by Wechsler, M E, Finn, D, Gunawardena, D, Westlake, R, Barker, A, Haranath, S P, Pauwels, R A, Kips, J C, Drazen, J M

“…We previously reported eight patients who developed Churg-Strauss syndrome in association with zafirlukast treatment for asthma and postulated that the…”
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Methods of examining induced sputum: do differences matter? by Kips, JC, Peleman, RA, Pauwels, RA

“…Analysis of induced sputum has been proposed as a direct, relatively noninvasive method for the evaluation of airway inflammation in diseases such as asthma or…”
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The potential role of tumour necrosis factor alpha in asthma by Kips, J C, Tavernier, J H, Joos, G F, Peleman, R A, Pauwels, R A

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Treating asthma, or is simple too simple? by Kips, J C

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Leukotrienes as therapeutic target in asthma by Pauwels, R A, Joos, G F, Kips, J C

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The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma by Abraham, B, Antó, JM, Barreiro, E, Bel, EHD, Bonsignore, G, Bousquet, J, Castellsague, J, Chanez, P, Cibella, F, Cuttitta, G

“…Since severe asthma is a poorly understood, major health problem, 12 clinical specialist centres in nine European countries formed a European Network For…”
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