Search Results - "Kipriyanov, Sergey M."

Antibody expressing pea seeds as fodder for prevention of gastrointestinal parasitic infections in chickens by Zimmermann, Jana, Saalbach, Isolde, Jahn, Doreen, Giersberg, Martin, Haehnel, Sigrun, Wedel, Julia, Macek, Jeanette, Zoufal, Karen, Glünder, Gerhard, Falkenburg, Dieter, Kipriyanov, Sergey M

“…Coccidiosis caused by protozoans of genus Eimeria is a chicken parasitic disease of great economical importance. Conventional disease control strategies depend…”
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Effect of Domain Order on the Activity of Bacterially Produced Bispecific Single-chain Fv Antibodies by Kipriyanov, Sergey M., Moldenhauer, Gerhard, Braunagel, Michael, Reusch, Uwe, Cochlovius, Björn, Le Gall, Fabrice, Kouprianova, Olga A., Von der Lieth, Claus-Wilhelm, Little, Melvyn

“…Bispecific single-chain Fv antibodies comprise four covalently linked immunoglobulin variable (VH and VL) domains of two different specificities. Depending on…”
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Generation of bispecific and tandem diabodies by Kipriyanov, Sergey M

“…Conventionally, antibody phage display has been used to isolate recombinant antibodies that are monovalent in their interaction with target antigens. These…”
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High-level periplasmic expression and purification of scFvs by Kipriyanov, Sergey M

“…The isolation of recombinant antibodies by phage display naturally leads to experiments to evaluate their biological and immunological properties. Although…”
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The Antigen-Binding Domain of a Human IgG-Anti-F(ab′)2 autoantibody by Welschof, Martin, Terness, Peter, Kipriyanov, Sergey M., Stanescu, Diana, Breitling, Frank, Dörsam, Heinz, Dübel, Stefan, Little, Melvyn, Opelz, Gerhard

“…Recent studies revealed an immunoregulatory role of natural IgG-anti-F(ab′)2 antibodies in both healthy individuals and patients with certain diseases. The…”
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Model structure of the immunodominant surface antigen of Eimeria tenella identified as a target for sporozoite-neutralizing monoclonal antibody by Jahn, Doreen, Matros, Andrea, Bakulina, Anastasia Y, Tiedemann, Jens, Schubert, Ulrike, Giersberg, Martin, Haehnel, Sigrun, Zoufal, Karen, Mock, Hans-Peter, Kipriyanov, Sergey M

“…Eimeria tenella is a coccidian parasite of great economical importance for poultry industry. The surface of Eimeria invasive agents, sporozoites and…”
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Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics by Kipriyanov, Sergey M, Moldenhauer, Gerhard, Schuhmacher, Jochen, Cochlovius, Björn, Von der Lieth, Claus-Wilhelm, Matys, E.Ronald, Little, Melvyn

“…To increase the valency, stability and therapeutic potential of bispecific antibodies, we designed a novel recombinant molecule that is bispecific and…”
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Effect of linker sequences between the antibody variable domains on the formation, stability and biological activity of a bispecific tandem diabody by Le Gall, Fabrice, Reusch, Uwe, Little, Melvyn, Kipriyanov, Sergey M.

“…Bispecific single-chain Fv antibodies comprise four covalently linked immunoglobulin variable (VH and VL) domains of two different specificities connected by…”
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Effect of tetravalent bispecific CD19xCD3 recombinant antibody construct and CD28 costimulation on lysis of malignant B cells from patients with chronic lymphocytic leukemia by autologous T cells by Reusch, Uwe, Le Gall, Fabrice, Hensel, Manfred, Moldenhauer, Gerhard, Ho, Anthony D, Little, Melvyn, Kipriyanov, Sergey M

“…To develop an effective antitumor immunotherapy for B-lineage non-Hodgkin's lymphoma, we constructed a tetravalent tandem diabody (tanDb) specific for both…”
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Synergistic Antitumor Effect of Bispecific CD19 × CD3 and CD19 × CD16 Diabodies in a Preclinical Model of Non-Hodgkin’s Lymphoma by Kipriyanov, Sergey M., Cochlovius, Björn, Schäfer, Holger J., Moldenhauer, Gerhard, Bähre, Alexandra, Le Gall, Fabrice, Knackmuss, Stefan, Little, Melvyn

“…Abstract To target NK cells against non-Hodgkin’s lymphoma, we constructed a bispecific diabody (BsDb) with reactivity against both human CD19 and FcγRIII…”
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Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: effect of valency on cell binding by Le Gall, Fabrice, Kipriyanov, Sergey M., Moldenhauer, Gerhard, Little, Melvyn

“…Single chain variable fragments (scFv) of the murine monoclonal antibody HD37 specific to human B-cell antigen CD19 were constructed by joining the V H and V L…”
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Generation of antibody molecules through antibody engineering by Kipriyanov, Sergey M

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High level production of soluble single chain antibodies in small-scale Escherichia coli cultures by Kipriyanov, Sergey M., Moldenhauer, Gerhard, Little, Melvyn

“…We have investigated the effect of growth and induction conditions on the production of soluble single-chain Fv antibody fragments in Escherichia coli under…”
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Generation and production of engineered antibodies by KIPRIYANOV, Sergey M, LE GALL, Fabrice

“…Various forms of recombinant monoclonal antibodies are being used increasingly, mainly for therapeutic purposes. This review specifically focuses on what is…”
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High-level periplasmic expression and purification of scFvs by Kipriyanov, Sergey M

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Generation and characterization of bispecific tandem diabodies for tumor therapy by Kipriyanov, Sergey M

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Generation of bispecific and tandem diabodies by Kipriyanov, Sergey M

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Immunosuppressive properties of anti-CD3 single-chain Fv and diabody by Le Gall, Fabrice, Reusch, Uwe, Moldenhauer, Gerhard, Little, Melvyn, Kipriyanov, Sergey M.

“…The mouse anti-human CD3 monoclonal antibody OKT3 is a potent immunosuppressive agent used in clinical transplantation. However, OKT3 therapy is associated…”
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Generation of recombinant antibodies by KIPRIYANOV, S. M, LITTLE, M

“…Recombinant antibody technology is opening new perspectives for the development of novel therapeutic and diagnostic agents. In this review we focus on advances…”
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Effect of tetravalent bispecific CD19×CD3 recombinant antibody construct and CD28 costimulation on lysis of malignant B cells from patients with chronic lymphocytic leukemia by autologous T cells by Reusch, Uwe, Le Gall, Fabrice, Hensel, Manfred, Moldenhauer, Gerhard, Ho, Anthony D., Little, Melvyn, Kipriyanov, Sergey M.

“…To develop an effective antitumor immunotherapy for B‐lineage non‐Hodgkin's lymphoma, we constructed a tetravalent tandem diabody (tanDb) specific for both…”
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