Search Results - "Kipp, Benjamin R."

The genomic landscape of small intestine neuroendocrine tumors by Banck, Michaela S, Kanwar, Rahul, Kulkarni, Amit A, Boora, Ganesh K, Metge, Franziska, Kipp, Benjamin R, Zhang, Lizhi, Thorland, Erik C, Minn, Kay T, Tentu, Ramesh, Eckloff, Bruce W, Wieben, Eric D, Wu, Yanhong, Cunningham, Julie M, Nagorney, David M, Gilbert, Judith A, Ames, Matthew M, Beutler, Andreas S

“…Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling;…”
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Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma by Graham, Rondell P., MBBS, Barr Fritcher, Emily G, Pestova, Ekaterina, PhD, Schulz, John, Sitailo, Leonid A., PhD, Vasmatzis, George, PhD, Murphy, Stephen J., PhD, McWilliams, Robert R., MD, Hart, Steven N., PhD, Halling, Kevin C., MD, PhD, Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Couch, Fergus J., PhD, Zhang, Lizhi, MD, Borad, Mitesh J., MD, Kipp, Benjamin R., PhD

“…Summary Patients with cholangiocarcinoma often present with locally advanced or metastatic disease. There is a need for effective therapeutic strategies for…”
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Ciliated Muconodular Papillary Tumors of the Lung Can Occur in Western Patients and Show Mutations in BRAF and AKT1 by Liu, Liping, Aesif, Scott W, Kipp, Benjamin R, Voss, Jesse S, Daniel, Silver, Aubry, Marie Christine, Boland, Jennifer M

“…Ciliated muconodular papillary tumors (CMPTs) are rare peripheral lung lesions, characterized by papillary architecture and ciliated columnar cells admixed…”
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Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions by Voss, Jesse S., CT, MB, Holtegaard, Leonard M., BS, MB, Kerr, Sarah E., MD, Fritcher, Emily G. Barr, CT, MB (ASCP), Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Zhang, Jun, MD, Highsmith, W. Edward, PhD, Halling, Kevin C., MD, PhD, Kipp, Benjamin R., PhD

“…Summary Cholangiocarcinoma is a highly lethal cancer of the biliary tract. The intrahepatic subtype of cholangiocarcinoma is increasing in incidence globally…”
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Identification of independent primary tumors and intrapulmonary metastases using DNA rearrangements in non-small-cell lung cancer by Murphy, Stephen J, Aubry, Marie-Christine, Harris, Faye R, Halling, Geoffrey C, Johnson, Sarah H, Terra, Simone, Drucker, Travis M, Asiedu, Michael K, Kipp, Benjamin R, Yi, Eunhee S, Peikert, Tobias, Yang, Ping, Vasmatzis, George, Wigle, Dennis A

“…Distinguishing independent primary tumors from intrapulmonary metastases in non-small-cell carcinoma remains a clinical dilemma with significant clinical…”
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An Optimized Set of Fluorescence In Situ Hybridization Probes for Detection of Pancreatobiliary Tract Cancer in Cytology Brush Samples by Barr Fritcher, Emily G, Voss, Jesse S, Brankley, Shannon M, Campion, Michael B, Jenkins, Sarah M, Keeney, Matthew E, Henry, Michael R, Kerr, Sarah M, Chaiteerakij, Roongruedee, Pestova, Ekaterina V, Clayton, Amy C, Zhang, Jun, Roberts, Lewis R, Gores, Gregory J, Halling, Kevin C, Kipp, Benjamin R

“…Background & Aims Pancreatobiliary cancer is detected by fluorescence in situ hybridization (FISH) of pancreatobiliary brush samples with UroVysion probes,…”
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ECPPF (E2F1, CCNA2, POLE, PPP2R1A, FBXW7) stratification: Profiling high-risk subtypes of histomorphologically low-risk and treatment-insensitive endometrioid endometrial cancer by Gonzalez-Bosquet, Jesus, Weroha, S John, Bakkum-Gamez, Jamie N, Weaver, Amy L, McGree, Michaela E, Dowdy, Sean C, Famuyide, Abimbola O, Kipp, Benjamin R, Halling, Kevin C, Yadav, Siddhartha, Couch, Fergus J, Podratz, Karl C

“…In endometrial cancer, occult high-risk subtypes (rooted in histomorphologically low-risk disease) with insensitivity to adjuvant therapies impede improvements…”
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Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms by Mackenzie, Robertson, Kommoss, Stefan, Winterhoff, Boris J, Kipp, Benjamin R, Garcia, Joaquin J, Voss, Jesse, Halling, Kevin, Karnezis, Anthony, Senz, Janine, Yang, Winnie, Prigge, Elena-Sophie, Reuschenbach, Miriam, Doeberitz, Magnus Von Knebel, Gilks, Blake C, Huntsman, David G, Bakkum-Gamez, Jamie, McAlpine, Jessica N, Anglesio, Michael S

“…Mucinous ovarian tumors represent a distinct histotype of epithelial ovarian cancer. The rarest (2-4 % of ovarian carcinomas) of the five major histotypes,…”
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Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma by Kipp, Benjamin R., PhD, Voss, Jesse S., BS, CT, MB(ASCP), Kerr, Sarah E., MD, Barr Fritcher, Emily G., BA, CT, MB(ASCP), Graham, Rondell P., MBBS, Zhang, Lizhi, MD, Highsmith, W. Edward, PhD, Zhang, Jun, MD, Roberts, Lewis R., MB, ChB, PhD, Gores, Gregory J., MD, Halling, Kevin C., MD, PhD

“…Summary Somatic mutations in isocitrate dehydrogenase 1 and 2 genes are common in gliomas and help stratify patients with brain cancer into histologic and…”
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Impact of Metastasectomy in the Multimodality Approach for BRAF V600E Metastatic Colorectal Cancer: The Mayo Clinic Experience by Johnson, Benny, Jin, Zhaohui, Truty, Mark J., Smoot, Rory L., Nagorney, David M., Kendrick, Michael L., Kipp, Benjamin R., Grothey, Axel

“…Background BRAF V600E mutations are present in 8%–10% of patients with metastatic colorectal cancer (mCRC) and portend poor prognosis. This study investigated…”
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Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein by Wang, Yu, Ding, Xiwei, Wang, Shaoqing, Moser, Catherine D, Shaleh, Hassan M, Mohamed, Essa A, Chaiteerakij, Roongruedee, Allotey, Loretta K, Chen, Gang, Miyabe, Katsuyuki, McNulty, Melissa S, Ndzengue, Albert, Knudson, Ryan A, Greipp, Patricia T, Clark, Karl J, Torbenson, Michael S, Kipp, Benjamin R, Zhou, Jie, Barrett, Michael T, Gustafson, Michael P, Alberts, Steven R, Borad, Mitesh J, Roberts, Lewis R

“…Highlights • We established a novel PDX mouse model bearing an FGFR2-CCDC6 fusion protein from a metastatic lung nodule of an iCCA patient. • FGFR inhibitors,…”
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Targeted next generation sequencing of endoscopic ultrasound acquired cytology from ampullary and pancreatic adenocarcinoma has the potential to aid patient stratification for optimal therapy selection by Gleeson, Ferga C, Kerr, Sarah E, Kipp, Benjamin R, Voss, Jesse S, Minot, Douglas M, Tu, Zheng Jin, Henry, Michael R, Graham, Rondell P, Vasmatzis, George, Cheville, John C, Lazaridis, Konstantinos N, Levy, Michael J

“…Less than 10% of registered drug intervention trials for pancreatic ductal adenocarcinoma (PDAC) include a biomarker stratification strategy. The ability to…”
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Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options by Bosquet, Jesus Gonzalez, Zhang, Qing, Cliby, William A, Bakkum-Gamez, Jamie N, Cen, Ling, Dowdy, Sean C, Sherman, Mark E, Weroha, S John, Clayton, Amy C, Kipp, Benjamin R, Halling, Kevin C, Couch, Fergus J, Podratz, Karl C

“…During the past decade, the age-adjusted mortality rate for endometrial cancer (EC) increased 1.9% annually with TP53 mutant (TP53-mu) EC disproportionally…”
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Combined “Infiltrating Astrocytoma/Pleomorphic Xanthoastrocytoma” Harboring IDH1 R132H and BRAF V600E Mutations by Yamada, Seiji, Kipp, Benjamin R, Voss, Jesse S, Giannini, Caterina, Raghunathan, Aditya

“…Pleomorphic xanthoastrocytoma (PXA) has rarely been reported in combination with infiltrating glioma, historically interpreted as a “collision tumor.”…”
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Intracranial angiomatoid fibrous histiocytoma with rhabdoid features: a mimic of rhabdoid meningioma by Vizcaino, M. Adelita, Giannini, Caterina, Chang, Howard T., Kipp, Benjamin R., Fritchie, Karen, Vaubel, Rachael

“…Angiomatoid fibrous histiocytoma (AFH) is an uncommon soft-tissue neoplasm that arises mostly in the extremities of young people and generally carries a good…”
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Fluorescence in situ hybridization compared with conventional cytology for the diagnosis of malignant biliary tract strictures in Asian patients by Chaiteerakij, Roongruedee, MD, PhD, Barr Fritcher, Emily G., CT (ASCP), Angsuwatcharakon, Phonthep, MD, Ridtitid, Wiriyaporn, MD, Chaithongrat, Supakarn, BSc, Leerapun, Apinya, MD, Baron, Todd H., MD, Kipp, Benjamin R., PhD, Henry, Michael R., MD, Halling, Kevin C., MD, PhD, Rerknimitr, Rungsun, MD, Roberts, Lewis R., MBChB, PhD

“…Background and Aims Fluorescence in situ hybridization (FISH) has improved the diagnostic performance of cytology for the evaluation of malignant biliary…”
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A mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimens by Renuse, Santosh, Vanderboom, Patrick M., Maus, Anthony D., Kemp, Jennifer V., Gurtner, Kari M., Madugundu, Anil K., Chavan, Sandip, Peterson, Jane A., Madden, Benjamin J., Mangalaparthi, Kiran K., Mun, Dong-Gi, Singh, Smrita, Kipp, Benjamin R., Dasari, Surendra, Singh, Ravinder J., Grebe, Stefan K., Pandey, Akhilesh

“…The COVID-19 pandemic caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has overwhelmed health systems worldwide and highlighted…”
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Sellar Region Atypical Teratoid/Rhabdoid Tumors in Adults: Clinicopathological Characterization of Five Cases and Review of the Literature by Paolini, Michael A, Kipp, Benjamin R, Sukov, William R, Jenkins, Sarah M, Barr Fritcher, Emily G, Aranda, Derick, SantaCruz, Karen S, Al-Dandan, Sadeq, Fisher, Pete, McDonald, William C, Bondurant, Charles P, Van Dyke Darkow, Grant, Giannini, Caterina, Parisi, Joseph E, Jentoft, Mark E, Raghunathan, Aditya

“…Abstract Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant CNS neoplasms that typically occur in children <2 years of age. These are…”
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Optimizing clinical cytology touch preparations for next generation sequencing by Murphy, Stephen J., Harris, Faye R., Smadbeck, James B., Serla, Vishnu, Karagouga, Giannoula, Johnson, Sarah H., Kosari, Farhad, Pierson, Karlyn E., Bungum, Aaron O., Edell, Eric S., Mansfield, Aaron S., Wigle, Dennis A., Kipp, Benjamin R., Vasmatzis, George, Aubry, Marie Christine

“…Intraoperative diagnosis is routinely performed on cytology touch preparations (TPs) from core needle biopsies (CNBs). Current interest promotes their utility…”
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SeekFusion - A Clinically Validated Fusion Transcript Detection Pipeline for PCR-Based Next-Generation Sequencing of RNA by Balan, Jagadheshwar, Jenkinson, Garrett, Nair, Asha, Saha, Neiladri, Koganti, Tejaswi, Voss, Jesse, Zysk, Christopher, Barr Fritcher, Emily G., Ross, Christian A., Giannini, Caterina, Raghunathan, Aditya, Kipp, Benjamin R., Jenkins, Robert, Ida, Cris, Halling, Kevin C., Blackburn, Patrick R., Dasari, Surendra, Oliver, Gavin R., Klee, Eric W.

“…Detecting gene fusions involving driver oncogenes is pivotal in clinical diagnosis and treatment of cancer patients. Recent developments in next-generation…”
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